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113 Cards in this Set
- Front
- Back
Describe "flushing" in relation to ewe management in the UK.
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Flushing is the provision of increased nutrition 6-8 weeks prior to breeding to increase body condition score and litter size in the pregnant ewe.
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What is the target month to send lambs to market in the UK?
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July
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What is the target scanning percentage in ewes in the UK?
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210%
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What is the target weaning percentage in UK sheep flocks?
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175-180%
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What weight should UK lambs be by the time they are 4 months old?
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35kg
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What is the typical perinatal lamb mortality in the UK?
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10-25%
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The birth of twin lambs of very different weights (ie 5.5kg and 3.5kg) suggests ___.
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three embryos implanted but one failed to develop.
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Dietary energy supply relative to metabolic demands can be determined in late gestation by ______.
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measuring the ewe's serum 3-OH butyrate concentration.
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Elevated 3-OH butyrate suggests _____.
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inefficient fatty acid utilisation due to the high glucose demand of developing foetuses and inadequate dietary proprionate or glucogenic amino acid supply of the ewe.
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What is the target 3OH-butyrate concentration in pregnant ewes?
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<0.8mmol/l
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What is the metabolisable energy (ME) of body weight loss in a ewe?
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36MJ
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What is the metabolisable energy (ME) of barley?
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12MJ (costs £100/tonne)
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An 3-OH butyrate level of >3.0mmol/l is diagnostic of ____ in the ewe.
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pregnancy toxaemia
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___ is a measure of short term protein intake.
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BUN
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___ is a measure of long term protein statuse.
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Albumin
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Lower albumin levels are normal in late gestation as what occurs?
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The manufacture of immunoglobulins and their accumulation in the udder.
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Name some pathological causes of post-partum lamb mortality.
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-distocia
-starvation -mismothering -hypothermia |
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Name some physiological causes of post-partum lamb mortality.
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-inadequate prenatal nutrition
-birth stress -inadequate post-partum nutrition |
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A 5kg lamb requires ___ of colostrum during its first 24hrs.
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1L
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Describe the demeanor of a lamb with:
a) rectal temperature 39-40°C b) rectal temperature 37-39°C c) rectal temperature <37°C |
a) healthy, suckling
b) weak, suckling c) weak, arched back, hollow flanks, unable to suckle |
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What are some common causes of ill thrift in the weaned lamb?
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-poor nutrition
-parasitic gastroenteritis -cobalt deficiency -selenium deficiency -liver fluke -respiratory disease -lameness -sheep scab -coccidiosis -brassica poisoning -border disease |
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___ sheep have decreased cobalt requirements.
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Pre-ruminant
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Soil pH above ___ can affect cobalt availability.
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5.8-6.3
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Pasture grown on waterlogged soil has a _____ than pasture grown on well drained soil.
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higher cobalt concentration
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Methylmalonic acid (MMA) accumulates in the plasma of cobalt deficient sheep as a result of ____.
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reduced Vit B12 co-enzyme activity
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Describe the pathophysiology of "Watery mouth" in lambs in relation to colostrum intake.
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Reduced colostrum intake not only decreases the immunoglobulins acquired by the lamb, but leads to the abomasal pH remaining neutral. Without the protective acidity of the abomasum, E. coli can rapidly divided and release endotoxins leading to disease.
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The main pathogenic role of enteric viruses (coronavirus, rotavirus) in neonatal lambs is ______.
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to enable the establishment of other enteric infections.
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Outbreaks of salmonellosis due to S. typhimurium or S. dublin are ___ in neonatal lambs.
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rare
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Why does enterotoxigenic E. coli only affect lambs less than 48hr old?
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The intestinal mucosa of the lamb only has receptors for the K99 adherence pili for the first 2 days of life.
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What bacteria is implicated in neonatal lamb polyarthritis (joint ill)?
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Streptococcus dysgalactiae
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Pain upon abdominal palpation of a neonatal lamb with a warm, discharging umbilicus indicates ____.
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infection has traveled up the umbilicus along the round ligament of the bladder or falciform ligament to the liver.
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Erysipelothrix rhusiopathiae infection in lambs can cause fibrinous polyarthrities, osteomyelitis, and even endocarditis. Why is this bacteria difficult to get rid of?
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It can survive for long periods in the soil at low temperatures.
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"White spot" abscesses in the liver of a neonatal lamb are indicative of what disease?
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Necrobacillosis (Fusobacterium necrophorum)
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A lamb born with scant wool that lacks crimp is suggestive of ___ deficiency.
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iodine
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Steely white wool in a sheep is suggestive of _____ deficiency.
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copper
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What causes mastitis in the ewe?
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Teat injury from poor milk production and overnursing or trauma allows the invasion of Staphylococcus aureus (skin commensal) or Mannheimia haemolytica (oral commensal).
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Only 2 of the 9 species of coccidia in sheep are pathogenic. What are they?
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Eimeria crandallis and E. ovinoidalis
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Which two sites in the ram are prone to urethral obstruction?
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-Vermiform appendage
-Sigmoid flexure |
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Why should ewe rations never be fed to rams or whethers?
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Ewe rations high in magnesium and cereals and beet pulp (low Ca and high Phosph) can induce urinary calculi.
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Louping ill is a diffuse, non-suppurative meningoencephalomyelitis caused by ________.
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flavivirus transmitted by Ixodes ricinus
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Tick pyaemia is a bacteraemia and joint ill due to _____.
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the injection of Staph. aureus by feeding Ixodes ricinus and potentiated by E. phagocytophilia.
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What is the causative agent of tick-borne fever in the UK?
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Erlichia phagocytophilia transmitted by Ixodes ricinus ticks.
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Name two primary organisms associated with ovine infectious keratoconjunctivitis.
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-Mycoplasma conjunctivae
-Chlamydophila psittaci |
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Name a common cause of traumatic keratitis in lambs.
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Entropion
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"Bright blindness", or progressive neuroretinal degeneration in sheep, is due to _____.
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chronic bracken ingestion.
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Listerial uveitis in the sheep is associated with ____.
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feeding silage
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What is the site targeted for local infiltration of anaesthetic for a third eyelid flap in the sheep?
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Auriculopalpebral block - where the dorsal border of the zygomatic arch meets the base of the ear.
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What is the site targeted for local infiltration of anaesthetic for enucleation in the sheep?
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Retrobulbar block
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What congenital ocular abnormality is seen in texcel sheep?
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Congenital Microophthalmia
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What factors can act as triggers to bring about clinical respiratory disease with Mannheimia haemolytica?
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-Environmental conditions (temperature, poor ventilation, dust)
-Stress (handling, weaning) -Reduced immunity (parasitism, etc) -PI3 virus -SPA -Mycoplasma/Bordatella |
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Name the three organisms associated with "Pasteurellosis" in sheep.
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-Mannheimia haemolytica
-Bibersteinia trehalosi -Pasteruella multocisa |
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Which "pasteruella" is responsible for the most common cause of sudden death in weaned lambs?
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Bibersteinia trehalosi
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Which non-progressive chronic pneumonia in sheep shows lymphocytic cuffing on histoloy?
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Atypical Pneumonia cased by Mycoplasma ovipneumoniae (and maybe Chlamydophila psittaci)
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What is the most pathogenic lungworm in sheep?
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Dictocaulus filaria
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Dictyocaulus filaria, Meullerius capillaris, and Protostrongylus refuscens are the three lungworms found in sheep. Where do each cause lung pathology?
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Dictyocaulus filaria: bronchi
Meullerius capillaris: alveoli Protostrongylus rufescens: bronchioles |
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Hyperglobulinaemia (>50g/l) in sheep indicates ____ such as ____.
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chronic infection; chronic suppurative pneumonia
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Name the infectious tumour that affects type 2 pneumocytes and Clara cells in sheep.
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Sheep Pulmonary Adenomatosis (Jaagsiekte)
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Name an important lentivirus in sheep that can cause four distinct syndromes.
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Maedi Visna!
Maedi- respiratory disease Visna- neurological disease mastitis arthritis |
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What upper respiratory condition is seen in short necked sheep breeds such as texels and suffolk in which trauma leads to edema, mucosal ulceration, and abscessation of the arytenoids?
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Laryngeal chondritis
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What condition in sheep is characterized by sneezing, head shaking, mucopurulent nasal discharge, and gadding?
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Nasal bot infestation - Oestrus ovis
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Abortion levels greater than ___ in sheep signal a likely infectious cause.
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2%
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What are the losses to the sheep farmer in terms of abortion rate and gross margin?
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1% abortion rate is a 2% loss of Gross Margin
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What advice would you give to a sheep farmer when dealing with an abortion?
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-Isolate the ewe
-dispose of abortion products by incineration or deep burial after samples are collected -Observe strict hygiene as most causes are zoonotic |
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What should be kept in mind when submitting samples for an abortion investigation in sheep?
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-collect fresh samples with minimal contamination
-collect samples from fetus and placenta -take vaginal swabs and blood from the ewe if no abortion products remain -supply several sets of samples for multiple investigations |
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What is the most common cause of infective abortion in ewes in the UK?
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Enzootic Abortion of Ewes (EAE) due to Chlamydophila abortus
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In Enzootic Abortion of Ewes, infected ewes will abort ____.
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-in the last 2-3 weeks of gestation if infected in early pregnancy
-in the last 2-3 weeks of the following year's gestation if infected in late pregnancy or non-pregnant |
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What is the second most common cause of abortion in UK sheep?
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Toxoplasmosis (T. gondii)
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Which type of abortion in the ewe is characterized by a wide range of signs from barren ewes to clinically normal but infected lambs depending on stage of gestation in which infection takes place?
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Toxoplasmosis
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In non-pregnant ewes, Toxoplasmosis will cause _____.
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long term immunity
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What cause of abortion in sheep is characterized by systemic illness of the ewe and a severely autolysed fetus and placenta?
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Salmonellosis (S. typhimurium, S. dublin, S. montevideo, S. abortus ovis)
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What is the causative agent of "Vibrionic abortion" in ewes?
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Campylobacter fetus fetus (intestinalis) or C. jejuni
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Border Disease is a pestivirus causing abortion in ewes and related to what two other disease in different species?
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-BVD in cattle
-Swine Fever in pigs |
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If a ewe becomes infected with Border disease before ____ days of gestation, the fetus will either die, or the lamb born will be persistently infected.
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60
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Ewes infected with Border Disease after ____ days gestation will have normal lambs.
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85
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_____ abortion in sheep is associated with feeding poor quality silage (pH>5).
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Listerial (L ivanovii and L. monocytogenes sensu stricto)
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Ewes and does are seasonal polyoestrus short day breeders, and exhibit peak fertility around _____.
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October/November
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Breeding outside of the natural season for a doe or ewe results in ___ and ___.
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lower fertility and lower prolificacy
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What is the average oestrus cycle of a ewe? A doe?
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Ewe: 16-17 days
Doe: 19-20 days |
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How long is the follicular phase of the oestrus cycle in a ewe?
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3-4 days
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In the pregnant ewe, progesterone is supplied by the ____, whereas the ____ produces progesterone in the doe.
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placenta; corpus luteum
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What disease of weaned lambs is characterized by blindness, dorsiflexion of the neck, hyperexcitability, and convulsions and response to thiamine treatment is marked?
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Polioencephalomalacia (Cerebrocortical Necrosis)
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What would be seen in the CSF of a lamb with a brain abscess?
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Elevated protein and white blood cell concentrations
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What are the three main clinical signs in encephalitis due to Listeria?
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-Depression (Ascending Reticular Activating System)
-Circling (vestibulo-cochlear nucleus) -Ipsilateral hemiparesis (damage to long tracts) |
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L. ____ can cause encephalitis as infection travels _____.
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monocytogenes; up the trigeminal nerve
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Listeria infection in pre-ruminant animals leads to ______.
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visceral listeriosis (septicaemia)
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Give three clinical signs seen in a sheep with unilateral vestibular disease.
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-Head tilt towards the lesion
-Horizontal nystagmus with fast phase away from lesion -Ipsilateral facial nerve paralysis |
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How is sarcocystis in sheep diagnosed?
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By histopathology on the central nervous system
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How is cerebellar abiotrophy diagnosed?
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By histopathology showing widespread Purkinje cell degeneration in the cerebellum.
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What disease might you suspect given the following clinical signs:
-lack of inflammatory cells on CSF tap -cerebellar dysfunction -transient collapse |
Scrapie
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What are the differences between the brain and spinal cord forms of visna in sheep?
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Brain form: head tilt, circling towards affected side, hypermetria
Spinal cord form: hypmetria, reduced flexion of distal limbs, reduced weight bearing in one pelvic limb with knuckling of fetlock |
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What is the average incidence of Footrot in sheep in the UK?
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10%
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What is the cost to the UK sheep industry for Footrot?
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£24 million per year
-£14 mill for prevention -£4 mill for treatment -£7 mill for production loss |
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Name five diseases associated with Fusobacterium necrophorum infection in sheep.
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-Neonatal necrobacillosis
-Footrot -Interdigital Dermatitis -Septic Pedal Arthritis -White Line Abscess |
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What is the causative agent of Footrot in sheep?
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synergism between Dichelobacter nodusus and Fusobacterium necrophorum
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Outline treatments for Footrot in sheep.
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-gentle foot paring with oxytetracycline spray
-footbathing (3% formalin or 10% zinc sulphate) -vaccination (Footvax) -antibiotics (treatment of choice) such as oxytet or pen/strep |
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What treatment can increase the severity of Ovine Digital Dermatitis?
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Formalin footbathing
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Motile spirochaetes have been implicated in which sheep foot disease?
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Ovine digital dermatitis
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Describe three ways in which toxoplasma gondii infection in the doe differs from the ewe.
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-no immunity develops in goats
-abortions may occur at subsequent pregnancies -public health risk as tachyzoites are passed in milk |
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What is the best treatment for septic pedal arthritis in sheep?
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Digital amputation
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What disease of the sheep limb is thought to be caused by excessive paring?
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Toe granuloma
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What condition of the sheep foot is suggested when purulent discharge is seen at the coronary band?
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White line abscess (toe abscess)
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Interdigital fibromas are thought to be ______ in tups.
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inherited
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Clostridium perfingens type B causes which disease in sheep?
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Lamb dysentery due to effects of beta and epsilon toxins
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Clostridium perfingens type D causes which disease in sheep?
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Pulpy kidney due to effects of epsilon toxin
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Clostridium perfingens type C causes which disease in sheep?
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Struck due to effects of beta toxin
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Clostridium sordelli causes which disease in sheep?
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Abomasitis
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Clostridium chauvei causes which disease in cattle and sheep?
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Blackleg
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Clostridium novyi type B causes which disease in sheep and sometimes cattle?
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Black disease
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What is the only clostridial disease in sheep that responds well to treatment?
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Malignant oedema responds to penicillin treatment
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Which clostridial disease is caused by the ingestion of toxin rather than organisms?
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Botulism
-type C & D in poultry litter -type B in carcass contaminated feed (silage) |
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For which clostridial disease is there no vaccine available?
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Botulism
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______ is the first organism to overgrow after death and may obscure diagnostic tests/cultures.
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Clostridium septicum
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What disease in cattle is caused by Clostridium novyi type C?
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Bacillary Haemoglobinuria (Redwater)
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