• Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

Card Range To Study

through

image

Play button

image

Play button

image

Progress

1/211

Click to flip

Use LEFT and RIGHT arrow keys to navigate between flashcards;

Use UP and DOWN arrow keys to flip the card;

H to show hint;

A reads text to speech;

211 Cards in this Set

  • Front
  • Back
Enzymes are made of what?
Protein
_____ are enzyme activators; includes some vitamins
Coenzymes
Which vitamins serve as coenzymes in the production of energy? (4)
Pantothenic acid, Thiamin (B1), Riboflavin (B2), Niacin (B3)
______ assists enzymes; usu minerals
Cofactor
Thyroxine ______blood sugar
Raises blood sugar by stimulating liver glycogenolysis and gluconeogenesis
In what age group is the BMR highest?
Ages 0-2 years
Basal metabolic rate (BMR) is measured when?
In the morning when reclining, awake, relaxed, at normal body temp, at least 12 hours after last meal, and several hours after strenuous activity.
Resting metabolic rate (RMR) is measured when?
Anytime of day, after eating or exercise: after short rest, controlled intake. More frequently measured than BMR.
What is the respiratory quotient for carbohydrate alone, fat alone, ad mixed intake?
CHO alone: 1
Fat alone: 0.7
Mixed intake: 0.85
To lower the respiratory quotient (RQ), which must be increased, CHO, fat, or protein?
Fat - increase the fat intake to lower the RQ
List the monosaccharides. (3)
Glucose, fructose, galactose.
List the disaccharides and their components (3)
Sucrose (glucose and fructose)
Lactose (glucose and galactose)
Maltose (glucose and glucose)
Sorbitol has ____ (same, more or less) calories compared to glucose
Same, but absorbed more slowly by passive diffusion. (may cause diarrhea)
Protein contains what percentage nitrogen?
16%
Which amino acids contain sulfur? (3)
Cysteine, cystine, methionine
List the essential amino acids
TV TILL PMH
Threonine, valine, tryptophan, isoleucine, leucine, lysine, phenylalanine, methionine, histidine
Amino acids that are conditionally essential during catabolic stress (2)
Arginine, Glutamine
Tryptophan is a precursor for what? (2)
Serotonin and niacin
Complete protein means what?
Contains all essential amino acids in sufficient quantity and ratio to maintain body and promote growth
If a pt is on a low protein diet, what types of protein should be given?
Those with a high biological value (HBV) (complete proteins)
____ % of protein can be converted to glucose
58% - making it an inefficient energy source
Soybeans are low in _____ (amino acid)
Methionine (this essential a.a. is missing in most vegetables)
Legumes are low in which amino acids? (3)
Methionine, cystine, and tryptophan.
Gelatin is low in which amino acids? (3)
Methionine, lysine, and contains NO tryptophan
What is a phospholipid?
A type of lipid in the cell membrane; controls passage of cpds in and out of the cell.
Most phospholipids are what?
Lecithins which contain choline, a lipotropic factor which helps prevent fat accumulation in the liver.
Lecithins functions through which enzyme?
LCAT
Choline
Choline is a lipotrophic factor that helps prevent the accumulation of fat in the liver.
Which oil is the most polyunsaturated?
Safflower
Which oil is the most unsaturated?
Canola
What are the 2 essential fatty acids?
Linoleic acid (omega-6)
Alpha-Linolenic Acid (omega 3)
What is a good source of linoleic acid?
Safflower has the most linoleic acid; soybean oil is also a good source.
What is a good source of alpha-linolenic acid?
Mainly from fish oils - EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid)
Lack of linoleic acid leads to what?
Poor growth, eczema, petechiae
If linoleic acid replaces CHO, it _____ LDL, _____ HDL (reduces or increases)
Reduces LDL, Increases HDL
If linoleic acid replaces saturated fat, it ______total cholesterol, ______HDL(reduces or increases)
Reduces total cholesterol, reduces HDL
Alpha-linolenic acid _____ hepatic production of triglycerides, ____ cholesterol levels
Decreases hepatic production of triglycerides; little effect on cholesterol levels
What does the omega sign of a fatty acid designate?
The location of the 1st double bond, counted from the METHYL END of the fatty acid.
_______ is the process of adding hydrogen converting a polyunsaturated fat, converting it into to a saturated fat.
Hydrogenation
Trans fatty acids have a ____ structure similar to that of saturated fatty acids
Linear
Best sources of trans fatty acids (3)
Margarines, shortenings, frying fats
What are the best sources of saturated fat (in order of predominance)?
Coconut oil, palm kernel, cocoa butter, butter, beef tallow, palm oil
What are the best sources of monounsaturated fat (in order of predominance)?
Olive oil, canola oil, peanut oil, sunflower oil
What are the best sources of polyunsaturated fat (in order of predominance)?
Safflower, corn, soybean, cottonseed, sunflower
List the types of fatty acids in butter (in order of predominance).
SFA, MUFA, PUFA
List the types of fatty acids in margarine (in order of predominance)
PUFA, MUFA, SFA
What is the formula to determine calories from alcohol?
(0.8)(proof)(ounces)
Where proof = % alcohol x 2
What is winterized oil?
Oil chilled so that fat with high melting points are filtered out (winterized oil is clear not cloudy - useful for salad dressing)
The toxic level of vitamin A
10,000 IU
Functions of vitamin A (2)
skin, vision
Sources of vitamin A
Dark green leafy vegetables, cantaloupe, fish, liver, carrots, fortified skim milk, apricots, sweet potato (richer colors = better sources)
Vitamin A needs (male and and female)
M: 900 micrograms RE
F 700 micrograms RE
Deficiency of vitamin A causes what? (3)
1. Nyctalopia (night blindness) which is an early sign and IS reversible
2. Xerophthalmia (corneal damage) - only after prolonged, severe deficiency - NOT reversible
3. Hyperkeratosis - dry scaly skin
What is the precursor for vitamin A?
Carotene is the precursor (provitamin) and is converted in intestinal mucosal cells
What is the precursor for vitamin D?
Cholesterol
7-dehydrocholesterol --> Vitamin D3. What is needed for this to take place?
UV light
Functions of vitamin D?
Ca, P metabolism
Sources of Vitamin D
Sunlight, egg yolk, fortified milk, cod liver oil
How much vitamin D is needed?
AI 5-15 mcg
(15 mcg = 600 IU)
What does Vitamin D deficiency cause?
Rickets - soft bones
Osteomalacia - adult rickets
7-dehydrocholesterol ---(UV light)---> Vit D3 (cholecalciferol) --> _____
D2 (ergocalciferol) (synthesized in plants)
Vitamin E is known as
tocopherol (alpha tocopherol is the only form that meets human requirements)
Vitamin E is one of the _____ toxic vitamins (least or most)
Least
What is the upper limit for vitamin E?
1000 mg
What are the functions of Vitamin E?
Antioxidant; also resists hemolysis of RBC
Sources of vitamin E
Vegetable oils, whole grains, green vegetables.
NIH list: wheat germ oil, almonds, sunflower seeds and oil, spinach, broccoli, etc.
Vitamin E needs
15 mg
What does a deficiency of vitamin E result in?
Hemolytic anemia
How is vitamin K synthesized?
By bacteria in the lower intestinal tract
What are toxicity symptoms of vitamin K?
There are NO specific toxicity symptoms
What are the functions of vitamin K?
Forms prothrombin in liver; aids blood clotting; given pre-surgery
Sources of vitamin K
Spinach, kale, collard greens, broccoli, brussels sprouts, parsley, green leafy vegetables.
How much vitamin K is needed?
M: 120 mcg
F: 90 mcg
What does vitamin K deficiency cause?
Slow clotting leading to hemorrhage
What interferes with vitamin K?
Mineral oil, antibiotics, anticoagulants
Vitamin B1 is also known as ____
Thiamin
Vitamin B1/thiamin is lost when temperature or pH _____
Rises (thiamin is heat stable in acid - when cooking)
Functions of Vitamin B1/thiamin
Oxidation of CHO; increased CHO in diet --> increased thiamin needs.
Source of Vitamin B1/thiamin
Grains, wheat germ, pork, liver; Better retained in meats cooked at lower endpoint temp, and roasted at lower oven temp
How much vitamin B1/thiamin is needed?
M 1.2 mg
F 1.1 mg
The lab value that reflects thiamin deficiency is_____
Plasma pyruvate --> thiamin deficiency
Deficiency of thiamin causes what?
Muscle weakness, foot drop, memory loss, beriberi, reduced erythrocyte transketolase
Vitamin B2 is also known as ____?
Riboflavin
Vitamin B2 is destroyed by ____
UV light
Functions of Vitamin B2/riboflavin
Energy release from protein; present in many coenzymes
Sources of riboflavin
Liver, kidney, meat, milk.
Also, lean meat, eggs, legumes, nuts, leafy green vegetables
How much Vitamin B2/riboflavin is needed?
M 1.3 mg
F 1.1 mg
Deficiencies of Vitamin B2/riboflavin lead to:
Growth failure, cheilosis (cracked lips), stomatitis (inflammation of the mouth); riboflavin deficiency affects cells with rapid turnover.
What is another name for B3?
Niacin or nicotinic acid
What is the precursor for B3/Niacin?
Tryptophan
What is the function of niacin?
Metabolism of CHO, protein, fat
Sources of niacin
Protein, peanuts
Niacin/B3 needs
M 16 NE
F 14 NE
NE = Niacin Equivalent;
1mg NE = 60 mg tryptophan = 1 mg niacin
Deficiency of niacin/B3 causes ____?
Pellagra: 4 D's:
Dermatitis, Diarrhea, Dementia, Death (may result from GI d/o or with alcoholism)
Precursor of folate
PABA
Properties/functions of folate
DNA synthesis, forms RBC in bone marrow (along with B12), acts as a coenzyme, *prevents neural tube defects*
Sources of folate
Liver, kidney, green leafy vegs, citrus fruits. Also, legumes (esp lentils, chickpeas, black beans), asparagus
Folate needs
400 mcg
Pregnancy: 600 mcg
Deficiency of folate leads to:
Megaloblalstic, macrocytic anemia; diarrhea, fatigue
Another name for vitamin B6
Pyridoxine
What are the functions of vitamin B6?
Coenzyme in amino acid metabolism: deamination, transamination
Increased protein --> _____ pyridoxine (B6) needs
Increased
Sources of pyridoxine/B6
Meat, wheat, corn, yeast, pork, liver; also, potato, banana, garbanzo beans, etc.
How much pyridoxine/vitamin B6 is needed?
M 1.3 - 1.7 mg
F 1.3 - 1.5 mg
Deficiency in B6/pyridoxine leads to
Seizures, anemia, dermatitis, glossitis
What is another name for vitamin B12?
Cyanocobalamin (contains cobalt)
Functions of B12
Coenzyme in protein synthesis; forms RBC
B12 is bound by what?
Intrinsic factor in gastric juice
Sources of B12
Liver, meat, milk (animal sources). Deficiencies are rare - usually due to lack of intrinsic factor
How much B12 is needed?
2.4 mcg
Deficiency of B12 leads to what?
Macrocytic, megaloblastic anemia; pernicious anemia - after gastrectomy or removal of ileum, due to lack of intrinsic factor
What is another name for pantothenic acid?
Coenzyme A
What is the function of pantothenic acid?
Energy synthesis of fatty acids
How is pantothenic acid synthesized?
By intestinal bacteria (possibly)
Sources of pantothenic acid
Animal foods, grains, legumes
How much pantothenic acid is needed?
AI 5 mg
Pantothenic acid deficiency
Rare deficiency - paresthesia in feet
What drug interferes with B6 (pyridoxine) metabolism>
INH - isoniazid - a TB drug
What is another name for vitamin C?
Ascorbic acid
What vitamin is the most easily destroyed?
Vitamin C (destroyed by heat, alkaline pH, oxidation)
Vitamin C functions
Formation of collagen, wound healing, aids iron absorption
Sources of vitamin C
Citrus fruits, potatoes, papaya, dark green, yellow vegetables, berries (esp strawberries), tomatoes, turnip greens, canteloupe
Vitamin C/ascorbic acid needs
75-90 mg
Vitamin C/ascorbic acid deficiency
Scurvy
Poor wound healing
Bleeding gums
Where is biotin found?
Synthesized by intestinal bacteria, found in many foods
Function of biotin
Coenzyme in fatty acid synthesis;
Converts pyruvate to oxaloacetate in gluconeogenesis
How much biotin is needed?
AI 30 mcg
Symptom of deficiency of biotin
Muscle pain
What are the functions of myo-Inositol
Binds calcium, zinc, iron, membrane structure
Sources of myo-Inositol
Outer husks of cereal grains, leafy green vegetables
What is myo-Inositol?
In plants as phytic acid; related to sugar; contains phosphorus; vitamin-like factor
What is the most abundant mineral in the body?
Calcium
Calcium is regulated by what hormone?
Parathyroid hormone
What aids in absorption of calcium?
Vitamin D, lactose, and acid
What interferes/reduces absorption of calcium?
Oxalates, phytates interfere with absorption (oxalic acid combines with calcium)
Calcitonin (thyroid) lowers serum calcium by what mean?
By inhibiting bone resorption
Functions of calcium
Blood clotting, cardiac function, nerve transmission
Sources of calcium
Dairy products, leafy vegetables, legumes
How much calcium is needed?
1000 mg - 1200 mg
Deficiency of calcium
Hypocalcemia --> tetany
Rickets
Phosphorus is part of ____, ____, _____, and ______
DNA, RNA, ATP, phospholipids
Function of phosphorus
Transports fat through lymph and blood, and in and out of body cells
Bone, teeth
Sources of phosphorus
Animal proteins: meat, poultry, fish, eggs, dairy, processed foods
Needs for phosphorus
700 mg
Food form of iron
Ferric
Most absorbable form of iron
Ferrous
Stored form of iron
Ferritin
What is the best assessment parameter of iron status?
Ferritin
Where is heme iron found?
Animal foods
Where is non-heme iron found?
Cereals, vegs, poorly absorbed
Function of iron
Oxygen transport
Sources of iron
organ meats, egg yolk, fish
What aids the absorption of iron
MFP (meat, fish, poultry) Factor, acid, vitamin C, calcium (oxalates bind iron, but if Ca is also present, it will bind to oxalates 1st, freeing up iron for absorption)
How much iron is needed?
M 8mg
F 18mg
Deficiency of iron
Anemia
Spoon-shaped nails
Fatigue
What does NOT aid the absorption of iron?
Eggs, tea, cow's milk, cheese
Functions of magnesium
Protein synthesis, stabilizes structure of ATP, works with calcium in neuromuscular transmission
Sources of magnesium
Abundant in foods (found as part of chlorophyll). Good sources include: halibut, almonds, cashews, soybeans, spinach, potato, peanuts, legumes, etc.
Magnesium needs increase with increases in what nutrients in the diet?
As PRO, Ca, D increase in diet, more Mg is needed
How much magnesium is needed?
M 420
F 320
Magnesium deficiency s/s
Rare: tremors
Functions of zinc
Increase taste acuity
Enhances insulin action
Sources of zinc
Meat, liver, eggs (animal products)
Excess zinc leads to ______ deficiency?
Copper
How much zinc is needed?
M 11 g
F 8 g
Deficiency of zinc causes what?
Poor wound healing
Reduced taste acuity
Iodine is part of ______
Thyroxine
Sources of iodine
Seafoods, iodized salt
Deficiency of iodine s/s
Goiter
How much iodine is needed?
150 mcg
Fluorine Function
Teeth, bones
Sources of fluorine
Soil, water
Amount of fluorine needed
M 4.0 mg
F 3.0 mg
Copper is attached to
Protein ceruloplasmin
Copper is essential for synthesis of ____
Hemoglobin
Copper aids absorption of ____
iron
Sources of copper
Liver, kidney, shellfish; also, whole grains, beans, nuts, potatoes, dark green leafy veg, yeast, dried fruits, black pepper
How much copper is needed?
900 mcg
In Wilson's disease, serum copper is ____ (reduced or increased)?
Reduced (copper deposits in liver, brain, and other organs) in Wilson's disease due to deficiency of ceruloplasmin
Selenium functions
Tissue respiration
Antioxidant
Source of selenium
Soil, grains, meat, fish, poultry, dairy
How much selenium is needed?
M 55 mcg
F 45 mcg
Deficiency of selenium
Myalgia, cardiac myopathy
Function of manganese
Central Nervous System
Sources of manganese
Whole grains, legumes, nuts
How much manganese is needed?
1.8 - 2.3 mcg
Deficiency of manganese
Weight loss, dermatitis
Functions of chromium
Aids insulin action
Maintains normal glucose metabolism
Sources of chromium
Yeast, oysters, potatoes, liver
How much chromium is needed?
25 - 35 mcg
Deficiency of chromium
Glucose intolerance
Lipid abnormalities
Functions of sodium
Acid/base balance
Osmotic pressure
Sources of sodium
Table salt, seafood, cheese
How much sodium is needed
500 to 3000 mg
Deficiency of sodium
Anorexia, muscle atrophy
Sodium is reabsorbed by _____
Aldosterone
Sodium is retained by ______
Steroids
Functions of potassium
Acid/base balance
Osmotic pressure
Sources of potassium
Fruits, vegetables, meat
How much potassium is needed?
2 grams
Deficiency of potassium
Muscle weakness
Aldosterone _______ (increases or decreases) excretion of potassium
Increases
Hyperkalemia can cause _______
Cardiac irregularities
Sulfur is part of which amino acids? (3)
Cysteine, cystine, methionine
Sources of sulfur
Animal proteins: meat, fish, poultry, eggs
How much sulfur is needed?
AI 425-550 mg
Choline is a component of what?
Lecithin
Choline transports lipids as _____
Acetylcholine
Sources of choline
Fat in eggs, milk, liver, soybeans
The 2 minerals that are important for glucose metabolism
Chromium and zinc
As energy expenditure of the body increases, the need for which vitamins increases? (4)
Thiamin, niacin, riboflavin, pantothenic acid (all are coenzymes)