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28 Cards in this Set
- Front
- Back
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Organ which is largest producer of IgM
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Spleen (antigen-processing center for macrophages)
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Opsonins (2) which enhance phagocytic activity of granulocytes and initiate the alternative complement pathway respectively
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Tuftsin and properdin
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Significance of the presence of Howell-Jolly bodies
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No remaining splenic tissue
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Most common location of accessory spleen
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Splenic hilum
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Most common non-trauma indication for splenectomy
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ITP
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Organisms for which post-splenectomy vaccinations should be given . . .
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H. influenzae, S. pneumoniae, and meningococci
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Mechanism of ITP
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Anti-platelet antibodies (IgG)
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Timing of platelet administration in relation to surgery for ITP
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After the splenic pedicle is clamped.
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Primary therapy for ITP
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Steroids
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Primary therapy for TTP
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plasmapheresis
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Administer if platelets >1,000,000 after splenectomy
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ASA
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Most common splenic tumor
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Hemangioma
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Most common malignant splenic tumor
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Non-Hodgkin's lymphoma
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Two indications for surgery for splenic cysts . . .
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symptomatic or >10 cm
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Syndrome with rheumatoid arthritis, splenomegaly and neutropenia
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Felty's
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Lysosomal storage disease with lipid accumulation in cells, hepatosplenomegaly and pancytopenia
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Gaucher's disease
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Most common congenital hemolytic anemia requiring splenectomy . . .
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Spherocytosis
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Defective protein in hereditary spherocytosis . . .
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Spectrin
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Treatment of hereditary spherocytosis . . .
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Cholecystectomy (pigmented stones) and splenectomy
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Type of Hodgkin's disease with worst and best prognosis respectively . . .
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lymphocyte-depleted and lymphocyte-predominant
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Most common type of Hodgkin's disease . . .
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nodular sclerosing
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Stage of Hodgkin's disease (lymphoma) with involvement of lymph nodes on both sides of the diaphragm . . .
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III
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Most common cause of chylous ascites . . .
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lymphoma
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Pathognomonic cell type in Hodgkin's lymphoma . . .
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Reed-Sternberg cell
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Most common cause of splenic vein thrombosis . . .
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Pancreatitis
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Three absolute indications for splenectomy . . .
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Splenic vein thrombosis, hereditary spherocytosis, echinococcal cyst
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Indications for treatment (embolization or ligation) of a splenic artery aneurysm . . .
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1. symptomatic
2. >2 cm diameter 3. female of childbearing age |
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Most common source of a splenic abscess . . .
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Hematogenous
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