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78 Cards in this Set
- Front
- Back
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Precocious puberty + BL hypertrophy of adrenals
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21 hydroxylase
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Hypoglycemia + ketosis
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Hypoglycemic coma
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Surgical removal of PT gland causes?
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2ndayr hypoparathyroid
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Young + HTN + enlarged yellow adrenal?
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Adrenal cortical adenoma
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Mets to distant places? (bone)
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Follicular carcinoma
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Papillary projections into thyroid & tall epithelial cells?
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Graves disease
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Lymphoid infiltrate + Hurtle cells?
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Hashimoto
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Giant cells
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Dequervain
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Nests + congo red stain
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Medullary carcinoma
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Enlarged follicles + flat cells
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Goiter
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Local invasion
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Medullary carcinoma
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Increased risk of non-Hodgkin's B cell lymphoma?
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Hashimotos
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Aggressive but confined tumor?
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Anaplastic carcinoma
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No dex suppression + Low ACTH + UL atrophy
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Ad adenoma
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No dex suppresion + HIGH ACTH
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Ectopic
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Mucor infections
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DKA
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High: ALP, CA, PTH and a LOW PO4?
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PT Adenoma
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Stones, bones, groans
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PT Adenoma
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High: PTH and PO4; Low Ca and Vitamin D; HIGH alp?
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Renal failure
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Super high PTH and hypercalcemia?
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Tertiary hyperPT
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High Vitamin D, Hypercalcemia, LOW PTH?
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Hypervitaminitosis
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Meningococcemia?
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WF syndrome
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Deficient iodine + goiter
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Diffuse nontoxic goiter
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Hyperfunctioning nodule + goiter
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Plummer syndrome
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URI
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Dequervain
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Calcitonin + amyloid stroma
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Medullary carcinoma
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Pancreas, pituitary, parathyroid tumors
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MEN1
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Islet hyperplasia
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Gestational DBM
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Amyloid deposition in islets
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DBM2
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Insulinitis
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DBM1 before clinical symptoms
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Scalloping of colloid
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Graves disease
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Antimicrosomal/ anti TGB?
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Hashimoto
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Young + euthyroid + nodule
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Follicular adenoma
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Autonomic & peripheral neuropathy
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Damage form sorbitol
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Long term steroids + adrenal crisis
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BL adrenal atrophy
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Accompanies addisons?
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Hashimoto
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Hypercalcemia + Osteitis FC
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PT Adenoma
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Men1 gene found in?
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Parathyroid neoplasia
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GNAS1 gene?
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GH adenomas
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RET gene?
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medullary & papillary carcinomas
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p53 mutation?
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anaplastic thyroid carcinoma
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VHL mutation?
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Pheochromocytoma
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PUD + recurrent ulcers + diarrhea?
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ZE syndrome (Gastrinoma)
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Man + cervical LN mets?
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Papillary carcinoma
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Hematogenous neoplastic spread?
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medullary and follicular carcinomas
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Suprasellar + young + squamoid tooth things + INC PRL + LOW ADH?
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Craniopharyngioma
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Galactorrhea + infertility + low libido
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PRL tumor
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<1cm, islet cell mass, hypoglycemia
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Islet adenoma
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Hypercalcemia + lung masses + lytic bone lessions
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Malignancy
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Lymphoid follicles + hurtle cells + pink
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Hashimoto
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Children + small blue cell tumor + elevated HVA in urine?
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Neuroblastoma
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Elevated urinary catecholamines?
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Pheochromocytoma
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No GH suppression?
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Acromegaly
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Hilar lymphadenopathy + addisons
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sarcoidosis
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HNFa + no insulin + severe hyperglycemia
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MODY 3 = most common
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AD inherited DBM + glucokinase mutation
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MODY 2
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Hyperglycemia + no ketosis
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Hyperosmolar coma
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Muscle wasting + large adrenals + other tumors
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Mets
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ADPKD causes?
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Secondary hyperparathyroid
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Hoarseness + SOB + mass extension + spindle cells
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Anaplastic carcinoma
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Orphan annie + RET/ NTRK1 + mutated TK
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Papillary carcinoma
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Adrenal insufficiency + no lactation + oligomenorrhea
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Sheehan syndrome
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Obese + cystic pit
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Empty sella
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Nodule + well differentiated + non invasive + hot
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Toxic adenoma
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Pax-8-PPARy fusion gene
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Follicular adenoma
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Increased Cyclin D1 mutation
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Parathyroid adenoma
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Mutatied AIRE gene?
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Autoimmune Polyendocrinopathy (specifically type 1)
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Adrenals + PTH + gonads + gastric parietal destruction?
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Autoimmune Polyendocrinopathy (specifically type 1)
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Cushings + virilization + LOW ACTH
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Adrenal cortical adenoma
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Nodular glomerulosclerosis
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DBM2
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TCF7L2 polymorphism
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DBM2
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IL2 + CTLA4 polymorphism
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DBM1
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Obese + angina + glucose intolerance
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DBM2
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Irridation + neoplasm of thyroid
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Papillary carcinoma
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Clinical DBM1 signs in a kid
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Absent islets (total destruction)
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Hyperfunctioning nodule
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Plummer syndrome
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K_ channel mutation + really sick neonate?
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Neonatal DBM
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Headaches + inferior to splenum of corpus callosum + superior to collicular plate + R/L thalamic pulvinar
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Pineloblastoma
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