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22 Cards in this Set
- Front
- Back
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CSF
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filgrastim and sargramostim
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Filgramstim AE
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bone pain, neutrophil demargination
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Sargramostim AE
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bone pain, pulmonary edema at high dose, no change in neutrophil trafficking
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Major side effect of G-CSF and GM-CSF
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solid tumors or leukemic pts after response
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Manage bone pain with…
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NSAID/APAP
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Thrombocytopenia
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platelet count <150,000/microliter
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thrombocytopenia results in
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decrease platelet production…bleeding
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prevention of thrombocytopenia
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oprelvekin
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Complete Response (CR)
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disappearance of all target lesions
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PR (partial response)
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dec in the sum of the longest diamete of target lesions
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PD (progressive dz)
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inc in the sum of the longest diameter of target lesions
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0.5 - 0.9 ANC (stage)
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3
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< 0.5 ANC stage
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4
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Creatinine: 3.1 - 6 x Normal = ___ stage
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3
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Creatinine: > 6 x normal = ____ stage
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4
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GI toxicity stage: >/= 7 stools/d, incontinent IV fluid
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3
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GI toxicity stage: life threatening-hemodynamically unstable
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4
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GI toxicity-stomatities: confluent ulcerations bleeding with mild trauma
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3
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GI toxicity-stamitities: tissue necrosis, spontaneous bleeding
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stage 4
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Liver toxicity (bilirubin): 3-10 x Normal
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stage 3
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Liver toxicity (bilirubin): >10 X normal
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stage 4
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aromatase inihibtor AE
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hot flashes, bone loss
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