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61 Cards in this Set
- Front
- Back
Area of absorption of folate
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jejunum
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Area of absorption of iron
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duodenum
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Area of absorption of bile acids
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ileum
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Area of absorption of fat soluble vitamins
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ileum
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Area of absorption of Vitamin B12
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ileum
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What Vitamin is often deficient with Isoniazid use? What symptoms does it cause?
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-Vitamin B6
-causes peripheral neuropathy |
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Why can carcinoid syndrome produce niacin deficiency?
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-Tryptophan is the precursor for both niacin and serotonin. If it is consumed making serotonin (which is what is produced in carcinoid syndrome) then there will not be enought left to make niacin=deficiency
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Which type of CV problems are associated with carcinoid synrome?
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Tricuspid regurgitation
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What is the first enzyme to become elevated in a heart attack?
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CK-MB
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What enzyme stays elevated longer in a heart attack-CK-MB or troponin?
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Troponin-->it is also more sensitive for heart attack
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ST elevations in leads V1-V5 represent ischemia to what part of the heart?
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Anterior heart, most likely a ruptured plaque in the LAD
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What passes through the diaphragm at the level of T8?
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IVC
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What passes through the diaphragm at the level of T12?
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Aorta
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What passes through the diaphragm at the level of T10?
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Esophagus
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Where is the usual location of Meckel's diverticulum?
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2 feet proximal to the ileocecal valve
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Which type of hernia is medial to the inferior epigastric artery?
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Direct inguinal hernia
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Which type of hernia occurs lateral to the inferior epigastric artery?
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Indirect inguinal artery
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What vessel is injured in an epidural hematoma?
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Middle meningeal artery
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What does an epidural hematoma look like on CT?
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Biconvex shaped lesion
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What vessel is injured in a subdural hematoma?
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Bridging veins
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What does a subdural hematoma look like on CT?
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Crescent shaped lesion
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What is the description of a subarachnoid hemorrage?
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"Worst headache of my life
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Chromosomal abnormality associated with DiGeorge syndrome
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22q11
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Chromosomal abnormality associated with Wilms tumor
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11p13
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Chromosomal abnormality associated with Angelman and Prader-Willi syndrome
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15q11-q13
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With what disease or cancer is the t(9;22) gene associated?
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-BCR-ABL fusion gene is associated with CML, ALL, and rarely AML
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With what disease or cancer is a 5p gene deletion associated?
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Cru-du-chat syndrome
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With what disease or cancers is the t(8;14) gene associated?
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-C-MYC region on chromosome 8
-Burkitt's lymphoma |
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With what disease or cancers is the t(11;22) gene associated?
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-Ewing's sarcoma
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With what disease or cancers is the t(11;22) gene associated?
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-APL, the M3 subtype of AML
-Gene prescence= responsiveness to ATRA therapy |
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Describe Acute erosive gastritis.
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-focal damage
-risk from: EtOH, NSAIDS, stress, cancer drugs, smoking -significant burns to body:Hurlings -Head trauma: Kushing's |
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Describe Chronic type A gastritits.
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-glandular destruction
-mucosal atropy -affects fundus -autoimmune -pernicious anemia results |
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Describe Chronic Type B gastritis.
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-chronic irritation due to h. pylori
-affects antrum -eventual mucosal atrophy, metaplasia, and carcinoma |
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Describe Menetrier's disease.
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-mucosal hyperplasia
-mucosa becomes thickened with concomitant atrophy of glands |
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What disease is a result of adenosine deaminase deficiency?
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SCID
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What disease is a result of a failure to produce interferon gamma?
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Hyper IgE or Jobs syndrome
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Describe Jobs syndrome
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-Neutrophils fail to respond to stimuli
-course facial features, retained primary teeth, eczema |
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Wht disease is a result of an inability to class switch?
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-hyper-IgM syndrome
-defective helper T cells |
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What disease is a result of a defect in the integrin CD18?
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leukocyte adhesion deficiency
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What coping mechanism are people with histrionic personality disorder likely to us?
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Regression (crying, etc)
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What coping mechanism are people with paranoid personality disorder likely to use?
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projection
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What coping mechanism are people with borderline personality disorder likely to use?
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Splitting
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In what cancer is Auer rods seen?
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AML
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What disease is cause by an increased relaxation of the lower esophageal sphincter?
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GERD
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A patient with achalasia and a birdbeak presentation on barium swallow has what problem with their lower esophageal sphincter?
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Inability of lower esophageal sphincter to relax
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Hemosiderin-laden macrophages are commonly seen in the lung in what sided heart failure?
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Left-sided heart failure
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What chromosomal translocation is associated for the best prognosis for a person with ALL?
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t(12;21)
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Describe Hereditary Spherocytosis.
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-Autosomal Dominant
-Hemolytic Anemia -Jaundice -Splenomegaly |
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What kind of immunoflourescence staining would confirm the presence of a leiomyosarcoma?
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Desmin staining
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What type of cell is calss diagnostically for CML?
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Smudge cell
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How is CML characterized, in general and on peripheral smear?
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-low leukocyte alkaline phosphatase due to immature granulocytes
-excess of neutrophils, metapyelocytes, basophils |
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What are the malignant cells in chronic and acute lymphocytic leukemia?
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B cells
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With what disease is CLL associated?
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Autoimmune hemolytic anemia, characterized by spherocytes, elevated reticulocytes, and positive Coombs test
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Von-Hippel-Lindau is a disease due to an error on which chromosome?
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chromosome 3
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Neurofibromatosis-1 is a disease due to an error on which chromosome?
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17
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Cystic Fibrosis is a disease due to an error on which chromosome?
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Chromosome 7
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Wilms Tumor is a disease due to an error on which chromosome?
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Chromosome 11
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Huntington's Disease is a disease due to an error on which chromosome?
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Chromosome 4
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In DKA, what will the H+ and K+ ions be like ?
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-Both will be elevated
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If a patient has symptoms of a stroke in the left lower extremity, what vessel is affected?
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Right anterior cerebral artery
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If a patient has symptoms of a stroke in the left upper extremity, what vessel is affected?
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Right middle cerebral artery
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