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50 Cards in this Set
- Front
- Back
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what is the main diff between dependence and abuse
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loss of control of use
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what are sx of wernickes disease
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ataxia, ocular palsy usually 6th nerve,
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what drugs cause a crash and burn depression in withdrawal
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cocaine and amphetamines
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what are sx of heroine withdrawal
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vomiting, nods, resp dep, supp couch reflex
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is narcotic withdrawal life threatening
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nope
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what are good drug tx for narcotic withdrawl
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clonidine, buspar
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what are some of the main risk factors for suicide
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men, older, fam hx, high social class, sudden drop in social class, physician, physical illness, terminal dx
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what are some meds that cause suicidal ideation
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reserpine, CS's, antihistamines, some cancer drugs, interferon
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what percentage of ppl that commit suicide have a mental illness
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95--80 percent of those have MDD, dmentia, deleriu,
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what does SAD PERSONS scale stand for
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sex, age, depression, prior attempt, etoh, rational thought loss, support lacking, organized plan. no spouse or no fam, sickness
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what are the levels of points from sad persons are what do they mean
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0-2 outpt follow up, set up appt
3-4 supervised- poss admit 5-6 hospitalize unles safe alternative 7-`10 hospitalize maybe be invol |
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what order of kinetics is alcohol processed by
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zero order- indep of concentration, elim rate depends on body wt or liver wt
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how high of alc level makes you have impaired motor, slurred speech, ataxia
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100-200
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what level of alc do you have to have emesis and stupor
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200-300
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what level alc do you have for coma
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300
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What level alc do you have for resp dep and death
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>500
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what is a blackout
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temp loss of anterograde mem
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what does alc do to sleep
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fragmentation of sleep pattern- deminiishes sleep early in sleep cycle
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if someone that is acutely intoxicated is also hypoglycemic when would you give them thiamine
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before glucose
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how much higher chance does an alcoholic have of getting cancer
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10x normal
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besides confusion what is another sign of korsakoff syndrome
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paralysis of external eye musclesm ataxia
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what is the method of choice for tx of alcohol withdrawal
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benzo taper ( chlorodiazepoxide, lorazepam or diazepam)
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what is this: life threatening, mental confusion, fluctuating loc, tremeor, agitation, inc autonomic
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delerium tremens
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what is the method of choice for tx of alcohol withdrawal
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benzo taper ( chlorodiazepoxide, lorazepam or diazepam)
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what is the rate of alcoholism in children if parent is one
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4x
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who is acamprosate for
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abstinent alcoholics, or ones with lever probs
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what is this: life threatening, mental confusion, fluctuating loc, tremeor, agitation, inc autonomic
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delerium tremens
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what are the effects when opioids bind to mu receptors
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spinal analgesia, resp dep, sedation, euphoria
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what is the rate of alcoholism in children if parent is one
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4x
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who is acamprosate for
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abstinent alcoholics, or ones with lever probs
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what is the method of choice for tx of alcohol withdrawal
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benzo taper ( chlorodiazepoxide, lorazepam or diazepam)
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what are the effects when opioids bind to mu receptors
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spinal analgesia, resp dep, sedation, euphoria
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what is this: life threatening, mental confusion, fluctuating loc, tremeor, agitation, inc autonomic
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delerium tremens
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what is the rate of alcoholism in children if parent is one
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4x
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who is acamprosate for
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abstinent alcoholics, or ones with lever probs
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what are the effects when opioids bind to mu receptors
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spinal analgesia, resp dep, sedation, euphoria
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what are the se of opioids
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resp dep, constipation, hypotension, pneumonia, urine retention
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what are the sx of opioid withdrawal
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muscle spasms, hyperalgesia, lacrimation, rhinorhea, yawning
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what opioid can be given in a patch and is also the primary anesthetic for CV surgery bc it doesnt cause cardiac depression
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Fentanyl
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what drugs are the shorter duration of action morphine types
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remifentanil, fentanyl, sufentanil. alfentanil
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what drug is used in the withdrawal treatment of the morhphines and heroines
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methadone
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why is methadone used for withdrawal treatment for morphines and heroines
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because it has a longer duration of action and gives the patient the same feeling
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what morphine type drug is preferred in obstetrics and why
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meperidine- bc is has a shorter duration of action and causes less resp dep
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what opioid is for neuropathic pain
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tramadol
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what is the MOA of tramadol
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mu receptor agonist, blocks reuptake of serotonin and NE
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how do the duration of action of naltrexone vs naloxone compare
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naltrexone- short DOA
naloxone- long DOA |
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what opioid is an antitussitive
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dextromethophan
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what is IR methylphenidate used for?
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used concurrenlty with long duration forms wither to provide a boost early in the morning or to smooth withdrawal in the late afternoon
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what do you used of pt is unresponsive to methylphenidate
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dextroamphetamine- its onset is in one hour and duration 5 hours
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what are side effects of stimulants
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headache, delay sleep onset, dec appetite, wt loss, tachy, motor and vocal tics
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