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15 Cards in this Set

  • Front
  • Back
major precursor of PG and thromboxanes
PGH2
function of Leukotriene B4
chemotaxis and activation of neutrophil adhesion molecules
PG that causes vasodilation and inhibition of platelet aggregation
PGI2
PG that produces fever
PGE2
PG that produces pain
PGE2
what cell adhesion glycoprotein is needed for granulation tissue formation?
fibronectin (binds o collagen, fibrin, and cell surface receptors (integrins)
Two mediators for angiogenesis
Vascular endothelial growth factor
fibroblastic growth factor
what occurs in G1 phase of the cell cycle?
production of RNA, protein, organelles, and CYCLIN D
what does epidermal growth factor do?
stimulate keratinocyte migration
stimulates granulation tissue formation
what does platelet-derived growth factor do?
stimulates proliferation of smooth muscle, fibroblasts, and endothelial cells
what are two functions of insulin growth factor-1?
stimulates synthesis of collagen
stimulates keratinocyte migration
where in the cell cycle do RB and P53 work?
Between G1 and S
what type of collagens are involved in dense scar tissue formation?
the scar tissue of granulation tissue must be remodeled (increases tensile strength)

metalloproteinases (collagenases) replace type III collagen with type I collagen

Zn is a cofactor for collagenases
What is nissl substances?
RER and free ribosomes
How fast do regenerated axons grow?
2-3mm/day