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11 Cards in this Set
- Front
- Back
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hypersplenism
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exess trapping and destr of RBC even notrmal ones
by enlarged spleen of any cause cytopenia correlate poorly with spleen size |
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tx steps
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possible splenectomy but depend on etiology
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etiology...
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inorganic cations
arsen copper org subst- chloramine from water purification with alum and chlorate amphotericin B toxin from clostr spiders snake venome |
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metab abnorm
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spur cell hemol anemia in severe liver disorder-0 poor prognosis
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red cells parasites
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malaria-- pl faciparum!! splenomegaly
babesiosis- protoz in RBC-- trombocytopenia, diss intravasc coagulation( DIC) deer tick vector most common in northeastern USA bartonellosis-- bartonells bacilliformis -- south America sand fly vector fever chills head ache musculoskeletal pain hemolysis, respons to antibiotics |
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trauma to RBC
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dialysis, pheresis ,
cardiac by pass |
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march hemoglobinuria
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running marching other repetitive contact- karate
hemoglobinemia and hemoglobinuria |
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fragmentational dialysis
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due to cardiac or large vessel abnormality
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description
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usually left side of heart etiolgy
mild hemolysis from severe aortic stenosis or aortic insuff, ruptured sinus of valsalve traumatic arteriovenous fistula aortofemoral bypass surgery more severe hemolysis from prosthetivc valves , especially with artic artifcial metallic defective or poorly functioning valves |
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ds
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increasing of anemia
slight reticulocytosis schistocytes chronic urinary iron loss( hemosiderin) may lead to iron defeciency |
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tx
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limit physical act
give iron if transfusion requirement- replace the valve |
