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11 Cards in this Set

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Which drugs can be used for Acute Gout?
indomethacin, colchicine
What drugs are used for chronic gout?
probenecid, sulfinpyrazone, allopurinol
How does colchicine work?
via inhibiting tubulin, MG can't get there and phagocytose
How do probenecid and sulfinpyazone work?
inhibit anion transporter in PCT
What are the side effects of probenecid and sulfinpyazone?
kidney stone
How does allopurinol work?
inhibit xanthine oxidase
What are the side effects of allopurinol?
GI intolerance, N/V/D
What are the side effects of colchicine?
Abd pain, diarrhea, vomiting
How does acetominophen work?
by inhibiting a varient of COX1 in the CNS
Why doesn't acetominophen work as an anti-inflammatory?
because it doesn't do COX2 in the periphery
Why aren't DMARDs used during pregnancy?
because they are tetratogens