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11 Cards in this Set
- Front
- Back
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Which drugs can be used for Acute Gout?
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indomethacin, colchicine
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What drugs are used for chronic gout?
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probenecid, sulfinpyrazone, allopurinol
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How does colchicine work?
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via inhibiting tubulin, MG can't get there and phagocytose
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How do probenecid and sulfinpyazone work?
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inhibit anion transporter in PCT
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What are the side effects of probenecid and sulfinpyazone?
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kidney stone
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How does allopurinol work?
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inhibit xanthine oxidase
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What are the side effects of allopurinol?
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GI intolerance, N/V/D
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What are the side effects of colchicine?
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Abd pain, diarrhea, vomiting
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How does acetominophen work?
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by inhibiting a varient of COX1 in the CNS
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Why doesn't acetominophen work as an anti-inflammatory?
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because it doesn't do COX2 in the periphery
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Why aren't DMARDs used during pregnancy?
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because they are tetratogens
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