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71 Cards in this Set
- Front
- Back
|
ACE Inhibitors |
-Captopril -Enalapril -Lisinopril -Benazepril -Fosinopril -Quinapril -Ramipril -Moexipril -Trandolapril -Perindopril |
|
Captopril
|
-ACE inhibitor -DOA: 6-12 hours -ADRs ➝ thiol so dygeusia (bad taste)/rash -Take one hour before meals |
|
Enalapril |
-Prodrug -No thiol -DOA ➝ 12-24 hours -IV form ➝ enalaprilat |
|
Lisinopril
|
-Not a prodrug so do not need to worry about esterases - No thiol - DOA➝ 24 to 36 hours (once a day dosing) -Most widely used – very potent with none of theadverse side effects |
|
Benazepril |
-Prodrug ➝ needs to be hydrolyzed |
|
Fosinopril
|
Fosinopril -Used for patients with diminished renal clearance -50% eliminated by hepatobiliary clearance -12 hour ½ life -24 hour DOA |
|
Quinapril
|
-Resistance to carboxylic peptidase allows it to be taken orally -Excreted renally -Prodrug |
|
Ramipril |
-Prodrug -24 hour DOA s-Excretedin urine and feces so less likely that you need dose adjustment in renallyimpaired patients |
|
Moexipril
|
-More extensively eliminated in feces -Should not be taken with food ➝ decreased bioavailability |
|
Trandolapril
|
-Similar to Ramipril -Eliminated through feces/urine |
|
Peridopril
|
b |
|
|
Angiotensin II Antagonists |
-Losartan -Valsartan -Irbesartan -Candesartan -Temisartan -Eprosartan -Olmesartan |
|
-Losartan
|
-AT1-selective receptor antagonist - |
|
-Valsartan
|
-Taking with food decreases bioavailability |
|
Irbesartan
|
-Spiro compound -Eliminated in feces -Not renal dependent |
|
Candesartan
|
-Cascading prodrug which allows for improved bioavailability |
|
Telmisartan
|
Angiotensin II Antagonist (ARB) -HI dose |
|
Eprosartan
|
b |
|
Olmesartan
|
b |
|
Aliskiren
|
b |
|
Reserpine
|
b |
|
Hydralazine
|
b |
|
Minoxidil
|
b |
|
Fenoldopam
|
b |
|
Methydopa
|
b |
|
Sodium Nitroprusside |
b |
|
Prazosin
|
b |
|
Terazosin
|
b |
|
Doxazoasin
|
b |
|
Clonidine
|
b |
|
Guanfacine
|
b |
|
Acetazolamide
|
b |
|
Methazolamide
|
b |
|
Furosemide
|
b |
|
Bumetanide
|
b |
|
Torsemide
|
b |
|
Ethacrynic
|
b |
|
Chlorothiazide
|
b |
|
Hydrochlorothiazide
|
b |
|
Methylclothiazide
|
b |
|
Indapamide
|
b |
|
Metolazone
|
b |
|
Chlorthalidone
|
b |
|
Amiloride
|
b |
|
Triamterene
|
b |
|
Spirinolactone
|
b |
|
Canrenone
|
b |
|
Eplerenone
|
b |
|
Mannitol
|
b |
|
Urea
|
b |
|
Glycerin
|
b |
|
Quinidine
|
b |
|
Procainamide
|
b |
|
Disopyramide
|
b |
|
Lidocaine
|
b |
|
Mexiletine
|
b |
|
Propafenone
|
b |
|
Flecainide
|
b |
|
Propranolol
|
b |
|
Metoprolol
|
b |
|
Esmolol
|
b |
|
Amiodarone
|
b |
|
Dronedarone
|
b |
|
Sotalol
|
b |
|
Ibutilide
|
b |
|
Dofetilide
|
b |
|
Digoxin
|
b |
|
Dobutamine
|
b |
|
Dopamine
|
b |
|
Inamrinone
|
b |
|
Milrinone
|
b |
