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9 Cards in this Set
- Front
- Back
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what is the mechanism of ethosuximide? Which cells?
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decreases Ca current in thalamic neurons?
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what anti-epileptic blocks NMDA receptors in hippocampal neurons?
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Valproic acid blocks NMDA receptors affecting potassium current
also affects Na & GABA receptors |
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what is primidone?
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antiepileptic that is converted to pheonbarbital and phenylethylmalonamide
all 3 are anti-convulsants |
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tx for absences seizures?
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ethosuximide (blocks T-type Ca2+ channels)
valproic acid can be used too, preferred if it's combined w/tonic clonic |
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what seizures can phenytoin tx?
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tonic-clonic seizures, status epilepticus
inhibits neuronal high-freq firing of action potentisls by blocking Na channels |
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what seizures can phenobarbital tx?
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generalized tonic-clonic
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tx for complex partial seizures?
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Carbamazepine
also useful for generalized tonic-clonic seizures can cause agranulocytosis or aplastic anemia |
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what seizures can valproic acid tx?
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tonic-clonic seizures
also absence seizures |
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what seizures does carbamazepine tx?
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drug of choice for complex partial
can also tx generalized tonic-clonic can cause agranulocytosis or aplastic anemia |
