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8 Cards in this Set
- Front
- Back
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Reactants of PDH complex
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Pyruvate, NAD+, CoA-SH
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Products of PDH complex
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AcetylCoA-SH, NADH, H+, CO2
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Three enzymes of PDH complex
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Pyruvate dehydrogenase
Dihydrolipoyltransacetylase Dihydrolipoyl dehydrogenase |
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Coenzyme of E1. What does E1 do?
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TPP
Removes CO2 from pyruvate |
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Coenzyme of E2. What does E2 do?
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Lipoamide and CoA
Transfers acetyl group to CoA creating acetyl-CoA(goes on to the CAC) |
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Coenzyme of E3. What does E3 do?
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FAD and NAD+
FAD --> FADH2 NAD+ --> NADH + H+ |
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Negative inhibitors of PDH complex
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ATP/ADP
NADH/NAD+ Acetyl-CoA/CoA |
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Positive inhibitors of PDH complex
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Pyruvate
Calcium |
