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9 Cards in this Set
- Front
- Back
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Ribonucleotide reductase is inhibited by:
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Hydroxyurea
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Thymidylate synthase is inhibited by:
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5 Flurouracil
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Dihydrofolate reductase is inhibited by:
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Methotrexate
Trimethoprim (Cotrimoxazole) Pyrimethamine |
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What's the function of Ribonucleotide reductase?
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Reducing ribonucleotides into deoxyribonucleotides for use in DNA synthesis
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What's the function of Thymidylate synthase?
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Converts dUMO to dTMP
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What does Thymidylate synthase need as a coenzyme?
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Tetrahydrofolate (THF)
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What's Cotrimoxazole?
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It's Trimethoprim + Sulphamethoxazole
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Do we make our own folic acid?
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No, we take it from the diet
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What's PABA?
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Folic acid precursor for used by bacteria only
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