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24 Cards in this Set
- Front
- Back
pulmonary hypertension primary
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young females
Raynaud's more likely entire vasculature of lung affected--obliterative |
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pulmonary htn secondary etiol
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chronic hypoxia copd apnea
polycythemia vera chronic or multiple PE any parenchymal lung dx |
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pulmonary htn scleroderma etiol
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pul htn out of proportion to lung dx, due to intimal proliferation
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pulmonary htn outside US etiol
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filiariasa
schistosomiasis |
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pulmonary htn PE
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loud P2, TR RV heave
R heart cath wedge >20mm Hg JVD w large V waves, liver pulsations, edema |
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pulmonary htn tx
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Bosentan--oral endothelin antagonist
ca ch blockers, sildenafil, anticoagulants, O2, epoprostenol |
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Goodpastures syn etiol/organs affected
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autoimmune M:F 3:1 lung/kidney
hemoptysis, Fe def anemia antiglomerular, anti BM linear depos IgG and C3 |
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Goodpastures tx and presentation
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tx immunosuppressives & plasmapheresis
think: dyspnea, hemoptysis and glomerulonephritis |
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alveolar proteinosis etiol
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bldup of surfactant/abnl alveolar macros
often hypoxemic from lg R-L sh tx severe: whole lung lavage |
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ABPA
what is it from path, labs who gets it? |
allergic rxn to aspergillus
IC deposits, hi serum IgE asthmatics/worsening sx periph eos |
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ABPA
types of HS reactions cxr findings |
type I wheal/flare
type III 5 hrs cxr central mucous impaction central bronchiectasis fingers in glove |
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ABPA tx
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long term steroidos, sometimes itraconazole
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Eosinophilic pneumonia 3 types
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1. benign eos pneumonia
2. acute eos pneumonia--ARDS etiol? 3. chronic eos pneumonia--50% asthma, female/mid aged, high eos in BAL high ESR |
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Chronic eos pneumonia
cxr and Tx |
bilat PERIPHERAL infiltrates
long term steroids |
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allergic granulomatosis of churg strauss etiol/organs
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necrotizing sm vessel vasculitis w eos
skin kidney, maybe neuropathy |
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allergic granulomatosis of churg strauss tx
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asthma + eos
cytotoxic agents + steroids |
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lymphomatoid granulomatosis
appearance/bx |
similar to wegeners/no upper resp, 50% --Histiocytic lymphoma, rarely affects kidneys
bx:mononuclear angiocentric necrotic vasculitis |
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lymphomatoid granulomatosis
organs, tx |
lung skin CNS periph nerve
cyclophosphamide/steroids |
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Wegener's granulomatosis
path, organs |
necrotizing granuloma
upper resp/sinus lungs kidneys |
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Wegener's granulomatosis
lung findings |
granulomatous pulmonary vasculitis w large and sometimes cavitary nodules
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Wegener's granulomatosis
labs, diagnosis, tx |
c-anca
nasal memb or open lung bx cyclophosphamide +/- steroids |
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Worsening asthma think of
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Churg Strauss
ABPA eosinophilic pneumonia |
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HLA B27 +
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ank spon
acute ant uveitis reiters reactive psoriatric arthritis juvenile RA |
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causes of pulmonary hemorrhage:
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common in pts w AML--but must also r/o Aspergillus
others: Goodpastures, pulmonary hemosiderosis, SLE, post bone marrow transplant |