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21 Cards in this Set

  • Front
  • Back
What is Pulmonary HTN?
MPAP > 25mmHg or > 30mmHg during exercise
How is Pulmonary HTN Classified?
Groups 1 -5
1. PAH
2. PVH
3. Resp/hypoxeima
4. Thombotic/embolic
5. Inflammatory affecting pul vasu
Mechanisms of pulmonary HTN?
A - Hypoxic vasoconstriction
B - Decreased area of pulmonary vascular bed
C- Volume and Pressure overload
Presentation of Pulmonary HTN?
Dyspnea
Fatigue
Substernal Chest pain
Syncope
symptoms of underlying disease
Findings on Physical Exam in Pulmonary HTN?
Loud (palpable) S2
RV heave
Right sided S4
Systoli Murmur (TR)
RV failure signs if severe
Ix for Pulmonary Htn?
CXR
ECG
Echo
Cardiac Cath
PFTs
Spiral CT
V/Q scan
Serology - ANA
Treatment of Pulmonary HTN?
O2
Treat underlying cause
Anticoag
vasodialors
CCB
PDE inhibitos
What is a PE?
Blood clot in pulmonary arterial tree with subsequent increase in pul vasuclar resistance and obstruction of blood supplying the lung parenchyma
What percentage of patients with a PE have clincal signs of a DVT?
Less than 30%
What does Virchow's triad consist of ?
Stasis
Endothelial damage
Hypercoagulable state
Presentation of PE?
Dyspnea
pleuritic chest pain
hemoptysis
syncope
leg sympotms (DVT?)
Findings on Physical Exam in a PE?
Tachypneea
tacycardia
SaO2 <92%
pleural rub
hypotension
fever
What is the scoring symstem used for PE? What does it give you?
Well's PE Score
Gives an indication based on 7 criteria of the probability of a PE (low, intermediate and High)
Ix for suspected PE?
D-dimer
ABG
ECG
CXR
Echo
V/Q scan
Spiral CT
Venous duplex Ultrasound or doppler
What is a D-dimer? Is it useful in PE?
D-dimer are products of thrombotic/fibrinolytic process.

Useful in testing low probabilty pts as test is sensitive.
Findings on ABG in PE?
Respiratory Alkalosis (think of V/Q curve)
ECG findings in PE?
Sinus Tachycardia
R Axis Dev
RBBB
S1-Q3-T3 wave changes
CXR findings in PE?
Most often is normal!!!!

Subsegmental atelectasis
pleural effusion (small)
Hampton's Hump - wedge shape infarcted area
Westermark's Sign - dilated proximal pulmonary artery with distal decreased lung markings (i.e. abrupt tappering of vessels)
Findings of PE on V/Q scan? Is this a good test?
V/Q segmental mismatch - give PE probability in low, indeterminant or high

Very Sensitive test - consider if pt has normal CXR and no COPD....if neg then PE ruled out.
Treatment of PE?
Admit
O2
Analgesics if chest pain
initial Anticoagulation:
-Get baseline: FBC, INR, aPTT, renal fx and LFTs
-SC LMWH or IV heparin (dalteparin 200U/kg or enoxaparin 1mg/kg)

Long Term Anticoagulation:
-Warfarin, start same day and overlap with LMWH until INR 2-3

IV Thrombolytic therapy - If massive PE with clincal signs (i.e hypotension, RHF)

IVC Filter - Only if DVT and absolute contrainidcation to anticoag or woreseing of PE after anticoag.

-
Thromboprophylaxis Indications?
Low Thrombosis risk (mobile medical patients /surgery less 30 mins) - no prophylaxis but early ambulation

Moderate Thrombosis Risk (most general, gyn, urological surgery and sick medical patients) - LMWH

High Thrombosis Risk( arthroplasty, hip fracture surgery, major trauma, spinal cord injury) - LMWH, Warfarin, Fondaparinux

High Bleeding Risk ( neurosurgery, intracrainal bleed, active bleeding) TED stockings, pneumatic compression devices