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33 Cards in this Set

  • Front
  • Back

centrilobular emphysema seen in

smokers

panacinar emphysema seen in

anti trypsin deficiency

spirometery in COPD

FEV1 decreased


FEV1/FEV less tha 70%


TLC increased


RV increased

FEV1 in COPD

<80% mild disease


50-80% moderate


30-50% severe


>30 very severe

treatment for COPD


(COPDERS)

smoking cessation (prolongs survival)


inhaled anticholinergic (first line)


inhaled b agonist (SABA as first line and LABA)


inhaled corticosteroids (fluticasone)


oxygen (dec mortality)


pulmonary rehab


vaccination

treatment for COPD exacerbation

b agonist and anticholinergics


IV corticosteroids (methylprednisolone)


antibiotics


Oxygen (keep O2 sat at 90-93%)

spirometery in asthma

decreased FEV1


decreased FEV1/FEV


increase in FEV1 by 122% with albuterol

mild intermittent


mild persistent


moderate persistent


severe persistent

symptoms <2 per week


symptoms not every day


daily symptoms


continual symptoms/frequent exacerbations

acute asthma treatment

- b agonist with nebulizer


- corticosteroids


- IV magnesium

lung cancer with lowest association with smoking and most common type overall

adenocarcinoma

time to consider a lung mass benign

2 years

overall 5 year survival of lung cancer

14%

treatment of NSCLC

surgery only without distant metastasis


radiation is an important adjunct

treatment for SCLC

combo of radiation and chemotherapy



Light's criteria

pleural protein/ plasma protien >0.5


pleural LDH/plasma LDH>0.6


LDH> 2/3 of serum LDH





primary simple pneumothorax

high recurrence rate (50% in 2 years)



secondary complicated pneumothorax

complication of underlying lung disease

sarcoidosis is a systemic granulomatous disease

noncaseating granulomas

Symptoms of sarcoidosis


AGRUELINGD

ACE, granulomas, rheumatoid, uveitis, erythema nodosum, lymphadenopathy (bilateral hilar lymphadenopathy), idiopathic, non caseating granulomas, gammaglobulinemia, vit D increase

diagnose sarcoidosis

transbronchial biopsy (must show non caseating granulomas)

treatment of sarcoidosis

systemic corticosteroids


most cases resolve in 2 years


methotrexate for progressive disease

asbestosis found in

lower lobes


higher risk of bronchogenic carcinoma and malignant mesothelioma

silicosis

upper lobes more common


egg shell calcifications


mining, stone cutting, glass manufacturing

hypoxemia tests

- Aa gradient


- response to supplemental oxygen


- PaCO2 level

ventilation is monitored by PaCO2

change with RR or TV

oxygenation is monitored by O2 saturation

change with FiO2 or PEEP

patients with ___ and ___ have highest risk of developing ARDS

sepsis, septic shock

does ARDS improve with 100% O2?

No- requires a high PEEP to prop open ariways with low TV


Bilateral diffuse pulmonary infiltrates

AC ventilation

delivers the highest level of PEEP to the lungs, risk of barotrauma


patient can initiate breaths at a faster rate than backup rate


all breaths are supported by ventilator

SIMV

patients can breath above the mandatory rate without help of ventilator

CPAP

no volume breaths are delivered but positive pressure is delievered



tracheostomy performed after ___ of being ventilator dependent

2 weeks

Treatment of PE

- O2


- anti coagulation immediately with LMWH


- long term anticoagulation with warfarin or novel agents and continue for 3-6 months


- tPA... maybe


- IVC filter