Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
21 Cards in this Set
- Front
- Back
|
beta agonists
|
albuterol
salmeterol formoterol |
|
|
glucocorticoids
|
beclomethasone
fluticasone budesonide ciclesonide |
|
|
combination drugs
|
advair
cingapor |
|
|
leukotriene
|
lipoxygenase
leukotriene receptor |
|
|
immunomodulators
|
omalizumab
|
|
|
anticholinergic
|
ipratropium
tiotropium |
|
|
ipratropium
|
short acting anticholinergic
Inhibit muscarinic receptor and reduce bronchospasm and mucus secretion Used for COPD |
|
|
tiotropium
|
long acting anticholinergic
Inhibit muscarinic receptor and reduce bronchospasm and mucus secretion Used for COPD |
|
|
omalizumab
|
anti-IgE
blocks allergic cascade |
|
|
lipoxygenase
|
inhbits smooth muscle contraction
|
|
|
leukotriene receptor
|
cant bind leukotriene
|
|
|
advair
|
combination of ICS and LABA
|
|
|
cingapor
|
combination of ICS and LABA
|
|
|
ciclesonide
|
prodrug - ICS
|
|
|
budesonide
|
ICS
Budesonide – few side effects but not very potent Conjugated in ester form When concentration falls, becomes de-ester and active Acts as reservoir of drug |
|
|
Fluticason
|
ICS
Fluticasone: Good receptor affinity to stay in lung Stays in lung At high doses, as a very high affinity for receptors outside of lung…high side effects |
|
|
beclomethoasone
|
ICS
Beclomethoasone: High pulmonary deposition But also highly absorbed in mouth Metabolites are active…lots of side effects |
|
|
idle particle size for delivery
|
2-5
|
|
|
albuterol
|
short acting beta agonist
hydrophilic |
|
|
salmeterol
|
long acting beta agonist
lipophilic |
|
|
formoterol
|
medium acting beta agonist
medium hydrophilic/lipophilic chain |
