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93 Cards in this Set

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Statistical test used when:
Variable 1 (Factor): Nominal (eg. treatment groups)
Variable 2 (Outcome): Ordinal (eg. categories of wellness)
Chi-square test
Statistical test used when:
Variable 1 (factor): Nominal (two levels, dichotomous)
Variable 2 (outcome): Continuous (eg. Blood Press)
T-test
Statistical test used when:
Variable 1 (factor): Nominal (3 or more levels)
Variable 2 (outcome): Continuous
ANOVA
Error that occurs when you mistakenly reject the Null:
Type I (alpha)
Error that occurs when you mistakenly accept the null:
Type II (beta)
Requirements of a Pearson Correlation:
Random selection of sample
Normality of traits measured
At least interval level measurement
Similar variation between X and Y
Linear relation between X and Y
What type of test to ordinal data require?
Nonparametric test
You could use this test when you have ordinal data that is not normal in the population in question:
Spearman Rank Correlation
(Spearman r)
Requirements of a Spearman correlation:
Random selection of sample
Both distributions of scores are in ordinal form
Linear relation between sets of scores
Chi-square test requirements:
Randomly selected samples
nominal level of measurement
independent cell entries
no expected cell frequency below 5
Degrees of freedom (chi-square)=
(rows-1)(columns-1)
4 variables specified in order to determine sample size:
Significance level, alpha (usually .05)
The desired power (80-95%)
Variability of the populations (SD's)
The amount of change from the null that we realistically want to detect
What would happen to the required sample size if alpha is decreased?
it would increase
What would happen to the required sample size if power is decreased?
it would decrease
What would happen to the required sample size if standard deviations were larger?
it would increase
What would happen to the required sample size if we decrease the differences we want to detect?
it would increase
What would happen to the required sample size if increase the differences we want to detect?
it would decrease
Random sample:
external valitidy to ensure that it is representation of the population
The presence of a microbe in a host to benefit the microorganism. Generally used to denote the possibility of causing disease:
Infection
Presence of microbes in a host which does not result in clinical disease and may be needed for health:
Colonization
GI tract flora are an example of a _____________ in the human body.
Colonization
The persistence of a microbe in a host with possibility of disease in the future without shedding of the organism in the interval:
Latent infection
Shingles from Varicella zoster is an example of a:
Latent infection
An infection can be ________ (like cholera or the flu) or __________ (like Hep B).
Acute; chronic
Two types of non-clinical infection (inapparent) for which transmission may still occur:
Preclinical; subclinical
Are you capable of spreading a virus in a latent infection prior to the onset of symptoms?
No
What percentage of typhoid infections are in people who are only carriers?
2-5%
The ability of the microbe to cause infection (enter, survive, multiply in host) but not necessarily cause symptoms:
Infectivity
Attack rate is equal to:
# infected/# exposed
The ability of the microbe to cause disease: (severity doesn't matter)
Pathogenicity
Attack rate for pathogenicity is equal to:
# of clinical cases/# infected
Degree of severity of the disease produced:
Virulence
Virulence and ____________ are often used interchangably, incorrectly.
Pathogenicity
Case fatality rate =
# fatalities/ # diagnosed cases
A sudden increase in the frequency of infection in a particular region:
Epidemic
An epidemic on a global scale (such as HIV, AIDS):
Pandemic
Why does HIV/AIDS occur more commonly in men?
Male-male sexual contact is primary source of transmission
Why is the prevalence of HIV increasing when incidence has been steady since the 1990s?
Duration is increasing due to better treatments
An infection that occurs regularly at a stable rate in a particular region:
Endemic
Malaria is ______ to sub-Saharan Africa
Endemic
A water-borne infection that is resistant to chlorine, other purifiers, and is hard to detect in epidemiological sense:
Cryptosporidiosis (fecal-oral tramsission)
Thousands have been infected with this from recreational water exposure
cryptosporidiosis
Residua of droplets which have evaporated to less than 5 microns
droplet nuclei
Two sites of infection from airborne vectors
upper respiratory infection or lung alveoli
Talking produces about ___ particles, coughing, ____, sneezing, ________>
100; 1000; >500000
Malaria, dengue, and yellow fever are examples of
Vector borne infecitons
Other living organisms which harbor microbe and transmit to susceptible host:
Vector
Inanimate objects which are contaminated and spread infection:
Fomites
An infection normally present in vertebrate animals but which can rarely spread and cause disease in humans; may be mild and require extensive exposure:
Zoonosis
An infection acquired in a hospital; chances much greater with presence of invasive devices or tubes such as catheters:
Nosocomial infection
Where do nosocomial infecitons occure the most?
The ICU
Requirements of an ANOVA:
Random selection of samples
Normality of traits in populaiton
Homogeneity of variance
At least one independent var. with three or more leves
One dependent var.
What is used to define an ANOVA?
the number of independent variables
ANOVA with multiple dependent variables:
Multivariate (MANOVA)
ANOVA where the dependent variable is 'corrected' for possible confounders:
Analysis of Covariance (ANCOVA)
An ANOVA is just a ______ with more than two levels of independent variables
t-test
An ANOVA is an _______, or an overall test.
omnibus
An ANOVA tells whether there is a difference between any groups, but not which groups that difference is in. What test must be done to find further information?
a post-hoc test
The proportion of diabetics in a group is pi where pi =:
# of diabetics in a group/# of people in the group
In many settings, this means the same thing as proportion:
probability
4 essential components of surveillance:
Case reporting
Data analysis
Communication of results
Application of findings
Systematic ongoing colleciton, collation, and analysis of data and the timely dissemination of information to those who need to know so that action can be taken:
Surveillance
3 types of surveillance:
Passive, active, and stimulated
Surveillance in which Physician, ICP, or lab reports cases as prescribed by state law without prompting
Passive surveillance
Surveillance in which regular examination and prompting done to ascertain presence or absence of cases:
Active surveillance
Surveillance in which intermittent prompting increases passive reporting:
Stimulated surveillance
Who publishes a list of diseases that should be reported?
Council of State and Territorial Epidemiologists (CSTE) and CDC
International health regulations require the mandatory declaration of what three diseases only?
Cholera, the plague, and yellow fever
Restriction of activities on the basis of exposure:
quarantine
Restriction of activities on the basis of infection until the infectious period has passed:
Isolation
Damage to an individual due to an energy exchange, or due to an acute disruption in the normal body energy process.
An injury
Five types of energy disruption in an injury:
Mechanical
Electrical
Chemical
Thermal
Radiation
What 3 types of death make up the injury portion of Years of potential life lost?
Unintentional injury, suicide, and homicide
What are the two biggest contributors to unintentional injury deaths?
Motor vehicle accidents, unintentional poisoning
"The story of the people"
Demography
The scientific study of the determinants and consequences of population trends (mortality, fertility, migration):
Demography
Reasons for measuring health/ill-health
Disease/injury prevention
Health promotion
Health services planning
Program evaluation
Which sex is more robust?
Female
Hypothesis a priori?
Before they collected the data
What is most directly associated with the accuracy of an estimate?
Standard deviation
variance
Standard error
Median
Range
Standard Error
When we accept the null, what is the probability of a type I error?
zero
What is the most effective method for reducing confounding in a study design?
Randomization
What effect does increasing alpha have on the chance of a type I error?
Increases the chance.
Only ____________ can help us determine if a result is 'significant' or suggests clinical significance.
effect sizes
Formula for Cohen's d:
(mean1 - mean2)/SD
Carrier status for typhoid fever is more common in which sex?
Females
Tuberculosis, measels, varicella, and possibly influenza can all be transmitted through:
Droplet nuclei
What percentage of ATV deaths are to passengers?
12
Type of bias which states that people receiving treatment are systematically different than the general population:
Berkson's bias
This bias is also known as prevalence-incidence bias; people with serious, more detrimental forms of a disease are less likely to show up in a point prevalence (not so much a problem with incidence)
Neyman's bias
Only study people who are homogenous for a known confounder:
restriction
Production of individuals improved solely because they were being watched:
Hawthorne effect
Mistaken belief that something is more likely to occur because it hasn't occured in a period of time:
Gambler's fallacy