Psychopharm/comps

Front 1

Depolarization

Back 1

1. resting state is -70
2. NA+ into cell leads to positive charge=-60, cell gets excited (membrane altered) and fires
3. this is action potential=firing = NT release.(glutemate)
4. Excitatory

Front 2

hyperpolarization

Back 2

1. CL- goes into cell, inhibitory, cell goes fr0m -70 to -90, will not fires. GABA (barbs)

Front 3

Synapses kinds

Back 3

excitatory and inhibitory

Front 4

GABA

Back 4

inhibitory, in 75-90 percent of brain cells

Front 5

Glutemate

Back 5

Excitatory in 75-90 percent of brain cells

Front 6

5HT

Back 6

Indole amine, from trypotophan makes you feel good, in 10 percent of brain cells

Front 7

NE and DA

Back 7

Catecholamines, from Tyrosine to L dopa to Dopa to DA to NE.

Front 8

ACh

Back 8

REsponsible for anticholinergic side effects caused by tricylics and antipsycotics (conventional)

Front 9

Reuptake

Back 9

NT is removed right after it exerts its effect on post synaptic membrane. Reuptake transport pump removes and deactinvates. Most common method of deactivating.

Front 10

SSRI's

Back 10

Prozac paxil, zoloft. (also lexapro and celexa)--sexual side effects, decrease orgasm decrease drive,(headache, sleepy, nervous)

Front 11

SNRI's

Back 11

1. NRI--walbuterin/zyban-no sexual side effect
2. SNRI-Effexor, Remrone and SEzone (cymbalta)
In low doses affect 5ht, middle doses 5HT and NE high doses also DA.

Front 12

Seraotonin-why not prescribed

Back 12

does not ex the Blood Brain Barrier.

Front 13

Prozac

Back 13

5 day half life, not a big problem to miss one, arousing give to letghargic patient

Front 14

Zoloft

Back 14

12 hour half life, can't miss a dose but can give drug holiday, arousing, give to lethargic patient

Front 15

Paxil

Back 15

Sedating, give to imsomniac patient