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40 Cards in this Set
- Front
- Back
The most widely used psychoactive drug is
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caffeine
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The majority of the metabolism of caffeine occurs in the
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liver
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The half-life of caffeine is
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3-10 hours
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Heavy caffeine causes
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anxiety, tremors, and insomnia
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The leading cause of death in the US
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nicotine
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Nicotine is readily absorbed in
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the lung, the mucus membrane, and the placenta
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Elimination or half life of nicotine is
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2 hours
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The majority of nicotine is metabolized in the
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liver
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the drugs that are most effective in smoking cessation include
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nicotine, bupropin, and varenicline
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The psychostimulants are thought to act most effective on
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dopamine
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Peripheral side effects of psychostimulants resemble activation of the
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sympathetic nervous system
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Cocaine is rapidly metabolized into
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an inactive metabaloid
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the positive reinforcing effects of cocaine are on
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dopamine
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in the absence of dopamine transporter cocaine is a
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positive reinforcer and behavioral stimulant
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The mechanism of the action of amphetamines is
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increasing the release of neurochemical transmuters
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the PNS effects of amphetamine are on
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nepinephrine
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ritalin's action is on
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dopamine
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the major psychoactive ingredient in marijuana is
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THC
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hashish and marijuana differ in their
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potency
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high doses of THC are
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rarely lethal
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THC blank calcium and blank neurochemical release at the presynaptic terminal
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inhibits, decreases
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the major action of anandamine appears to be on the
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presynaptic inhibition
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THC is metabolized to inactivate and activate metabolites within
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the first passing
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effects of THC
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increases appetite, impairs cognition, and impairs encoding, consolidation, and retrieval of memory
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Barbiturates are
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sedative hypnotics
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The most common cause of death combining benzo and alcohol because of what
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respitory arrest - stops breathing
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the sedative hypnotic properties of sedatives results in
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effects on GABA
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GABA is a
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derivative of glutamate
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The elimination or half life of barbiturates is anywhere from
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a few minutes to longer than 48 hours (all of the brave)
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Barbiturates blank memory and blank REM sleep
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suppress, decrease
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Treatment for overdose of barbiturates is
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respitary and cardiovascular support
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Mickey finn is
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chloral hydrate and ethanol
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The difference in the benzodiazapine is in the
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pharmokinetics
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Compared with young adults the elderly
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dont metabolize benzo's as easily
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Benzodiazepines facilitate binding at the
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GABA receptor
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The brain site mediating panic attacks are the
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amygdala, the orbitofrontal cortex, and the insula
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Presently, the drug of choice for treatment of chronic anxiety is
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antidepressants or atypical antipsychotics (not benzo's)
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The effects of benzodiazepines include
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sedation, anxiolytics, and muscle relaxation (all of the above)
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Ambien is prescribed for
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insomnia
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Buspirone is useful in treating
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depression
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