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40 Cards in this Set

  • Front
  • Back
The most widely used psychoactive drug is
caffeine
The majority of the metabolism of caffeine occurs in the
liver
The half-life of caffeine is
3-10 hours
Heavy caffeine causes
anxiety, tremors, and insomnia
The leading cause of death in the US
nicotine
Nicotine is readily absorbed in
the lung, the mucus membrane, and the placenta
Elimination or half life of nicotine is
2 hours
The majority of nicotine is metabolized in the
liver
the drugs that are most effective in smoking cessation include
nicotine, bupropin, and varenicline
The psychostimulants are thought to act most effective on
dopamine
Peripheral side effects of psychostimulants resemble activation of the
sympathetic nervous system
Cocaine is rapidly metabolized into
an inactive metabaloid
the positive reinforcing effects of cocaine are on
dopamine
in the absence of dopamine transporter cocaine is a
positive reinforcer and behavioral stimulant
The mechanism of the action of amphetamines is
increasing the release of neurochemical transmuters
the PNS effects of amphetamine are on
nepinephrine
ritalin's action is on
dopamine
the major psychoactive ingredient in marijuana is
THC
hashish and marijuana differ in their
potency
high doses of THC are
rarely lethal
THC blank calcium and blank neurochemical release at the presynaptic terminal
inhibits, decreases
the major action of anandamine appears to be on the
presynaptic inhibition
THC is metabolized to inactivate and activate metabolites within
the first passing
effects of THC
increases appetite, impairs cognition, and impairs encoding, consolidation, and retrieval of memory
Barbiturates are
sedative hypnotics
The most common cause of death combining benzo and alcohol because of what
respitory arrest - stops breathing
the sedative hypnotic properties of sedatives results in
effects on GABA
GABA is a
derivative of glutamate
The elimination or half life of barbiturates is anywhere from
a few minutes to longer than 48 hours (all of the brave)
Barbiturates blank memory and blank REM sleep
suppress, decrease
Treatment for overdose of barbiturates is
respitary and cardiovascular support
Mickey finn is
chloral hydrate and ethanol
The difference in the benzodiazapine is in the
pharmokinetics
Compared with young adults the elderly
dont metabolize benzo's as easily
Benzodiazepines facilitate binding at the
GABA receptor
The brain site mediating panic attacks are the
amygdala, the orbitofrontal cortex, and the insula
Presently, the drug of choice for treatment of chronic anxiety is
antidepressants or atypical antipsychotics (not benzo's)
The effects of benzodiazepines include
sedation, anxiolytics, and muscle relaxation (all of the above)
Ambien is prescribed for
insomnia
Buspirone is useful in treating
depression