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111 Cards in this Set
- Front
- Back
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imipramine
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TCA
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Amitriptyline
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TCA
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Trimipramine
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TCA
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Nortriptyline
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TCA
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TCA least likely to cause orthostatic hypotension
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Nortryptiline
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Desipramine
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TCA
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TCA with least sedating and least anticholinergic side effects
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Desipramine
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Clomipramine
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TCA
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TCA with most serotonin specific activity
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Clomipramine
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TCA used for treatment of OCD
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Clomipramine
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Your patient has a QRS complex that is widened by >100 msec what drug class is this toxic effect from?
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TCAs
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YOu have a patient who ODed on TCAs what drug treats the OD?
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IV sodium Bicarb
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Major complications of this class of drugs is convulsions, coma and cardiotox
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TCAs
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Phenelzine
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Nardil, MAOI
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Tranylcypromine
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Parnate, MAOI
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Isocarboxiazide
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Marplan, MAOI
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Fluoxetine
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Prozac, SSRI
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Which SSRI has the longest half life and therefore does not need to be tapered?
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Fluoxetine (prozac)
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Sertraline
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Zoloft, SSRI
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Which SSRI has the highest risk of GI side effects?
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Sertraline (zoloft)
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Paroxetine
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Paxil, SSRI
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which SSRI is the most serotonin specific and the most activating?
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Paroxitine (paxil)
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Fluvoxamine
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Luvox, SSRI
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which SSRI is only approved for OCD?
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Fluvoxamine
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Citalopram
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Celexa, SSRI
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Escitalopram
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Lexapro, SSRI
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VEnlafaxine
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Effexor SNRIs (5HT and NE)
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Antidepressant known to increase BP
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Venlafaxine (SNRI)
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Withdrawl symptoms from this drug include sensation of electric sparks
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venlafaxine (SNRI)
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Bupropion
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Welbutrin, NDRI (NE/Da)
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Antidepressant used for smoking cessation
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Buproprion (wellbutrin, NDRI)
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Antidepressant used in seasonal affect disorder and adult ADHD
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Buproprion (wellbutrin, NDRI)
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What antidepressant is free of sexual side effects?
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Bupropion (wellbutrin, NRDI)
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What are the two contraindications to Buproprion? (wellbutrin)
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Eating disorder and seizure disorder
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Nefazodone
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Serzone, SARIs (5HT antagonist and reuptake inhibitor)
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Trazodone
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Desyrel SARIs (5HT antagonist and reuptake inhibitor)
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Two drugs that are very useful for depression with anxity and depression with insomina
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Nefazodone and trazodone (SARIs)
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antidepressant with priapism as a major side effect
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Trazadone (SARIs)
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Mirtazapine
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Remeron, NASAs (NE and 5HT antagonists)
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Drug used for depression in patients who need to gain weight
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Mirtazapine (remeron NASAs)
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Antidepressant that causes agranulocytosis as a rare side effect
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mirtazapine (remeron NASAs)
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Chlorpromazine
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Thorazine, low potency typical antipsychotic
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Thioridazine
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Mellaril, low potency typical antipsychotic
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Two typical antipsychotics that can be given in long acting forms
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Haloperidol and Fluohenazine- both high potency typicals
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Haloperidol
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Haldol high potency typical antipsychotics
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Fluphenazine
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high potency typical antipsychotics
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Trifluoperazine
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high potency typical antipsychotics
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Perphenazine
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high potency typical antipsychotics
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Pimozide
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Orap high potency typical antipsychotics
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Subjective anxiety and restlessness, objective fidgetiness
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akathesia
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sustanied contractions of the muscles of the neck tongue and eyes
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dystonia
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Parkinsonisms, akathesia, dystonia and hyperprolactinemia are all what kind of side effects? Which class of drugs is the most likely to cause these?
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EPS and typical high potency antipsychotics
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Amantadie, dyphenylhidramine, and benxotropine are all used to treat what kind of side effects?
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EPS
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What is thought to cause tardive dyskinesia?
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an increase in the number of Da receptors which causes lover leves of Ach
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What antipsychotic causes deposits in the lense and cornea?
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chlorpromazine (thorazine)- low potency typical
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what antipsychotic causes irreversible rentinal pigmentation
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Thioridazine (mellaril)- low potency typical
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which antipsychotic causes blue grey skin discoloration?
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chlorpromazine (thorazine)- low potency typical
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Which class of antipsychotics is most likely to lower the seizure threshold?
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low potency typicals
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what are the three treatment steps in TD?
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STOP THE MEDS!!! can try anxiolytics or cholinomimetics
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Clozapine
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Clozaril- atypical antipsychotic
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Risperidone
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Risperdal- atypical antipsychotics
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Quetiapine
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Seroquel- atypical antipsychotic
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Olanzapine
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Zyprexa- atypical antipsychotic
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Ziprasidone
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Geodon- atypical antipsychotic
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which two antipsycotics are also FDA approved for the treatment of maina?
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Quetiapine (seroquel) and Ziprasidone (geodon) both atypical antipsychotics
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Which atypical antipsychotic is known to cause agranulocytosis?
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Clozapine
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Which atypical antipsychotic is associated with a 2-5% incidence of seizures
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clozapine
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Which atypical antipsychotic can be known to cause hyperlipidemia, glucose intollerance, weight gain, and liver toxicity?
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Olanzapine (zyprexa)
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Which atypical antipsychotic requires monitoring of LFTs
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Olanzapine (zyprexa)
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which atypical antipsychotic requires q6month slit lamp exam to look for cataracts?
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quetiapine (seroquel)
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what two classes of drugs tend to alter Li levels?
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NSAIDS (decrease) (not ASA) and Diuretcs
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What is the theraputic range for Li?
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.7-1.2
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what is the toxic level of Li?
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1.5
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what is the lethal level for Li?
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>2
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How long is the lag time till Li works?
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5-7 days
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A patient presents with change in ms, coarse tremors, convulsions and then dies what psych med did they od on?
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Li
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Carbamazepine
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Tegretol, Mood stabilzer
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Drug that is first line for RAPID CYCLING bipolar
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Carbamazepine (tegretol)
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Onset of action for carbamazzepine
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5-7 days
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Leukopenia, Hyponatermia, aplastic anemia, agranulocytosis are all S/E of this mood stabilizer
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carbamazepine (tegretol)
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To start this drug you need to order a CBC and LFTs both must be monitored regularly
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carbamazepine (tegretol)
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valproic acid
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depakene, mood stabilizer
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hemorrhagic pancreatitis, hepatotox, thrombocytopenia are all side effects of which drug
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valproic acid
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which mood stabilzer causes increase in LFTs
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carbamazepine
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which mood stabilizer is safe in pregs?
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NONE
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clordiazepoxide
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Librium- long acting benzo
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diazepam
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valium- long acting benzo with short onset of action
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Flurazepam
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Long acting benzo
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Alprazolam
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xanax- medium acitng benzo
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Clonazepam
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Klonopin, medium acting benzo
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Lorazepam
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Ativan- medium acting benzo
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Temazepam
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Restoril- medium acting benzo
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Oxazepam
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Short acting benzo
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Triazolam
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Rapid onset short acting benzo
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zolpidem
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ambian- non benzo anxiolytic/ hypnotic but works on GABA, no tolerance or dependency
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Zaleplon
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Sonata- like zolpidem but has shorter half life (hypnotic)
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Buspirone
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BuSpar non benzo anxiolytic
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what is the onset of action for buspirone (BuSpar)
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1-2 weeks
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what is the site of action of Buspirone (BuSpar)
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5HT-1a receptor parital agonist
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which two classes of drugs produce anti- HIstiamine, Adrenergic and muscarinic S/E?
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TCAs and low potency antipsychotics
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what is the mech of action of TCAs?
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inhibition of the reuptake of NE and 5HT
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how do you treat hypertensive crisis?
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IV phentolamine (alpha blocker)
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what is the risk of schizophrenia with one parent?
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10%
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what is amok syndrome?
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people from malayan origin that have violent or furious outburst with homicidial intent with out motive and claim of amnisia
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what is ganser sydrome?
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patient who responds to a question with an approximate or outright ridiculous answer, get altered consciousness, hallucinations, convesion phenomenon and amneisia
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what is catalepsy?
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the assumption of an immobile position that is constantly maintained, especially after an exam
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what antidepressant is safe in pregs?
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fluoxitine
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what psych drug tends to cause reversible hair loss?
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Divalprex sodium (bipolar)
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what test should be used tolook for neglect?
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Rey- Osterrieth figure
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what psych test is used to look for organic brain disease?
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Bender Gestalt
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what psych test determines hemispheric language dominance?
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Wada test
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