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74 Cards in this Set
- Front
- Back
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What are positive symptoms in psychotic disorders?
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delusions
disorg speech/behav hallucinations agitation |
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What receptors are positive psychotic symptoms assoc with?
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dopamine receptors
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What are negative symptoms in psychotic disorder ?
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Flat affect
Social withdrawl Anhedonia apathy poor thought |
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What are the most effective treatment for negative symptoms?
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Atypical antipsychotics
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What receptors are negative symptoms assoc. with?
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Muscurinic
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How long does schizo have to be for it to be a diagnosis?
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6 mo and impair baseline functioning
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What symptoms have to be present the positvie or neg in schizo?
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Positive
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Who does schizo present in at an earlier age, male or female?
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male 15-25
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What is the diagnosis for
<6 mo but >1month? |
schizophreniform
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When positive symptoms are present for <1 month what is the psycotic diagnosis?
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Brief psychotic disorder
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When there is a history of symptoms for many years with no impairment of baseline functioning what should you think of?
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delusiona disorder and personality disorder
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What type of ddelusions are present in a delusional disorder?
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NONBizarre
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What are you thinking if therer is a history of positive symptoms with no impairment of baseline function in a psychotic disorder?
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pERSONality disorder---schizotypal personality disorder
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What does schizotypal personality disorder present with?
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peculiar thinking and social isolation but doesn't involve psychosis
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Do people with delusional disorder or personality disorder respond to antipsychotics?
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NO
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What is the preferred therapy to treat schizotypal personaility disorder or delusional disorder?
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psychotherapy
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What are you thinking if you have auditory and olfactory hallucinations, feelings of deja vu or dissociation from surroundings?
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Temporal lobe epilepsy
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what is the risk of suicide attempt in schizo in a lifetime?
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50 percent
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how many of suicidal attemps are successful in schizo pts?
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10 percent
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Who are at a greater risk of depression and suicide ater the episode of psychosis resolves?
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schizophreniform
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When there is a history of symptoms for many years with no impairment of baseline functioning what should you think of?
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delusiona disorder and personality disorder
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What type of ddelusions are present in a delusional disorder?
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NONBizarre
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What are you thinking if therer is a history of positive symptoms with no impairment of baseline function in a psychotic disorder?
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pERSONality disorder---schizotypal personality disorder
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What does schizotypal personality disorder present with?
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peculiar thinking and social isolation but doesn't involve psychosis
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Do people with delusional disorder or personality disorder respond to antipsychotics?
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NO
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What is the preferred therapy to treat schizotypal personaility disorder or delusional disorder?
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psychotherapy
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What are you thinking if you have auditory and olfactory hallucinations, feelings of deja vu or dissociation from surroundings?
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Temporal lobe epilepsy
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what is the risk of suicide attempt in schizo in a lifetime?
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50 percent
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how many of suicidal attemps are successful in schizo pts?
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10 percent
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Who are at a greater risk of depression and suicide ater the episode of psychosis resolves?
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schizophreniform
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When there is a history of symptoms for many years with no impairment of baseline functioning what should you think of?
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delusiona disorder and personality disorder
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What type of ddelusions are present in a delusional disorder?
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NONBizarre
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What are you thinking if therer is a history of positive symptoms with no impairment of baseline function in a psychotic disorder?
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pERSONality disorder---schizotypal personality disorder
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What does schizotypal personality disorder present with?
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peculiar thinking and social isolation but doesn't involve psychosis
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Do people with delusional disorder or personality disorder respond to antipsychotics?
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NO
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What is the preferred therapy to treat schizotypal personaility disorder or delusional disorder?
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psychotherapy
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What are you thinking if you have auditory and olfactory hallucinations, feelings of deja vu or dissociation from surroundings?
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Temporal lobe epilepsy
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what is the risk of suicide attempt in schizo in a lifetime?
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50 percent
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how many of suicidal attemps are successful in schizo pts?
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10 percent
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Who are at a greater risk of depression and suicide ater the episode of psychosis resolves?
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schizophreniform
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What is the greatest risk factor for progression ot schizo?
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Schizophreniform...2/3 actually presgress
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Who in general have a better prognosis and repond better to treatment?
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Females
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Which type of schizophrenia pt. are more responsive to treatment than those with other kinds?
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Paranoid
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What is the intial steps in managmt of acute psychotic disorders if case desribes bizarrre or paranoid symptoms?
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Hospitalize the pt.
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What should you do in the management of agitation of schizophrenia?
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Give Benzo for agitation
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How long should antipsychotic meds be given for?
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6 months
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what is the most effective therapy to prevent further episodses?
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Antipsychotic meds
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When are long-term antipsychotic meds given?
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if there is a history or repeat episodes
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What elese other than giving benzo for agitation, and starting antipsychotic meds should be done to treat schizo?
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long-term psychotherapy
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What has an immediate quieting effect in acute psychotic attacts (schizo, depression with psychotic features, mania in bipolar)
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Antipsychotic
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What delays relapses in schizo?
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antipsychotic meds
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What are 2 other indications for antipsychotics?
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1.Sedation when Benzo are contraindicatied or as an adjunct
2. Movement d/o Huntington and Tourette |
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Why do you give antipsychotics in movement disorders?
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to suppress tics and vocalizations
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What type of antipsychotic is fluphenazine?
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High Potency
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What type of antipsychotic is haloperidol
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High potency
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What type of antipsychotic is thioridazine
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Low potency
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What type of antipsychotic is chlorpromazine
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Low potency
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What type of antipsychotic is risperidone
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Atypical
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What type of antipsychotic is olanzapine
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Atypical
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What type of antipsychotic is quetiapine
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Atypical
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What type of antipsychotic is clozapine?
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Atypical
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What is the A/E of fluphenazine or haloperidol?
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EPS
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What is the A/E of olanzapine,risperidone, quetiapine, clozapine?
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only clozapine may cause agranulocytosis
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What is the A/E of low potency tioridazine, chlorpromazine
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Anticholinergic effects
More sedation more postural hypotension |
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What are the advantages of High potency antipsychotics...
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less sedating
few anticholinergic effects Less hypotension Can be used as depot shot Give IM for acute psychosis if unable to do Oral |
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What are the adv. of Low potency?
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Less likely to do EPS
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What is the advantage of atypical antipsychotic
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DOC
Greater effects on neg. symptoms Little or no risk of EPS |
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What are the anticholinergic effects of low potency antipsychotics?
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DRY everything up
hypotension urinary retension dry mouth blurry vision, and delirium |
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What is thioridazine assoc. with on EKG/
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Prolong QT syndrome and arrythmias
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What is thioridazine assoc. with for the eyes after many years of usage?
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Retinal pigmentation
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What are common alpha blockade see in men and reason of non-compliacane in males?
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impotence and inhib of ejaculation
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What is a common reason for non-compliance of antipsych meds in females?
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Wt. gain
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What is the most appropriate treatment antipsychotic to initiate in a newly diag schizo pt. with insomnia?
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Olanzapine, quetiapine, aripiprazole
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A schizo pt. has been maintained on olanzapine for the past 6 months. He complains of daytime sedation, and has lost 2 jobs in the past month because of impaired performance, what is the next step in management?
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risperidone
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