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12 Cards in this Set
- Front
- Back
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Psychostimulant - Indications |
1. Narcolepsy 2. Nocturnal enuresis (self-wetting) 3. Hyperkinetic syndrome 4. Pharmacological interview |
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Psychostimulant - Drugs |
Amphetamine methamphetamine phenmetrazine methlyphenidate |
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Psychostimulant - C/I |
Anxiety Depression/sucidal behaviour/ drug abuse history psychosis/ aggressiveness HTN/ IHD Mania |
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Psychostimulant - Adverse mechanism |
1. Inaccuracy of mental functions 2. Risk of dependence 3. induction of anxiety 4. increased self-importance, aggressiveness, exhaustion, death 5. Tachycardia/ htn 6. Increase tolerance hangover |
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Psychostimulant - Mechanism and clinical effects |
Mechanimism: increase conc of NE and DA in Synapse Clinical effect: increase of lucidy of conscioussness/ psychomotor pace/ memory recollection/ acelleration of thinking/ decrease fatigue/ shortening of sleep peroid/ decrease apeptite |
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Notropic drugs USE/ Mechanism |
Use:
1. Quantitive and qualitative impairment of consciousness 2. impairment ofmemory/intellect/learning ability Mechanism: enhance adaptation ability of neurons, keep heostasis/ increase glucose and o2 use in brain/ increase atp pool/improve persfusion in the brain/ scavenge o2 radicals/ increse ach synthesis |
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Nootropic drugs - names |
1. Piracetam 2. Pyritinol 3. meclofenoxate 4. cinnarizine 5. Pentoxifylline 6. Dihydroergotoxine |
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Nootropic drugs - Adverse effects |
1. insomnia 2. psychic tension 3. excitement |
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Cognition enhancing drugs Use and mechanism |
Use: slowing down progression of mild alzheimers dementia for 1-2year
Mechanise, Inhibitors of acetylcholiniesterase/ butrlycholinesterase stimulators of nicotinic receptors. |
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Cognition enhancing drugs |
Donzepil/ rivastigmine/ galantamine |
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Cognition enhancing drugs ( A/E) |
1. nausea/ vommiting/ diarrgoe 2. stomache ache 3.vertigo/ headache |
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Memantine : mech/indication/a/e |
-Antagonis of NMDA glutamate - ionotropic receptors -supresses neurotoxitiy of exitatory amino acids indication: Medium - sever dementia A/E deliriium/ fatigue/headache/sleepiness |
