Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
42 Cards in this Set
- Front
- Back
Treatment for:
Disinhibition, slurred speech, ataxia, coma, blackouts GGT |
alcohol intoxication:
- naltrexone - disulfiram |
|
Treatment for:
tremor, tachycardia, hypertension, malaise, seizures, delirium tremens, tactile hallucinations, agitation |
alcohol withdrawal:
- benzodiazepines for DTs |
|
Treatment for:
CNS depression, N/V, constipation, pupillary constriction (pinpoint pupils), seizures |
Opioid (heroin, morphine, methadone) intoxication:
- naloxone - naltrexone |
|
Treatment for:
anxiety, insomnia, sweating, anorexia, piloerection, fever, rhinorrhea, nausea, diarrhea, cramps, yawning |
Opioid (heroin, morphine, methadone) withdrawal:
- symptomatic - methadone - naloxone + buprenorphine |
|
Treatment for:
respiratory depression due to barbituate intoxication |
- symptomatic (increase BP, assisted respiration)
|
|
Treatment for:
anxiety, seizures, life-threatening cardiovascular collapse, delirium |
Barbituate withdrawal
- symptomatic |
|
Treatment for:
amnesia, ataxia, somnolence, minor respiratory depression, worse with alcohol |
Benzodiazepine intoxication
- Flumazenil (competitive GABA antagonist) |
|
anxiety, seizures, tremor, insomnia
|
benzodiazepine withdrawal
|
|
psychomotor agitation, pupillary dilation, hypertension, euphoria, prolonged attentiveness/wakefulness, arrythmia, delusions, hallucinations, fever
|
amphetamine intoxication
|
|
depression, lethargy, stomach cramps, headache, hunger, hypersomnolence
|
amphetamine withdrawal
|
|
Treatment for:
euphoria, psychomotor agitation, pupillary dilation, hallucinations (tactile), paranoid ideations, angina |
cocaine intoxication:
- benzodiazepines |
|
Severe depression, suicidality, hypersomnolence, severe psychological craving for drug
|
cocaine withdrawal
|
|
restlessness, insomnia, increased diuresis, muscle twitching, arrythmia
|
caffeine intoxication
|
|
headache, lethargy, depression, weight gain
|
caffeine withdrawal
|
|
restlessness, insomnia, anxiety, arrythmia
|
nicotine intoxication
|
|
Treatment for:
irritability, headache, anxiety, weight gain, craving |
nicotine withdrawal
- buproprion - varenicline |
|
belligerence, impulsiveness, fever, vertical and horizontal nystagmus, ataxia, homicidality, psychosis, delirium, tachycardia
|
PCP (phenylcyclidine) intoxication
|
|
Depression, anxiety, restlessness, anergia, disturbed thought/sleep
|
PCP (phenylcyclidine) withdrawal
|
|
Anxiety or depression, visual hallucinations, flashbacks, pupillary dilation, delusions
|
LSD intoxication
|
|
euphoria, anxiety, paranoid delusions, perception of slowed time, impaired judgment, social withdrawal, increased appetite, dry mouth, hallucinations
|
marijuana intoxication
|
|
irritability, depression, insomnia, nausea, anorexia peaking in 48 hours, lasting 5-7 days
|
marijuana withdrawal
|
|
What is suboxone? When is it used?
|
Naloxone + buprenorphine (partial opioid agonist):
- long acting - fewer withdrawal Sx than methadone - lower abuse potential (oral) |
|
confusion
ophthalmoplegia ataxia |
Wernicke's encephalitis (thiamine deficiency)
|
|
memory loss
confabulation personality change |
Korsakoff's pyschosis (thiamine deficiency)
|
|
In what order to symptoms appear during DTs?
When do Sx peak? |
autonomic hyperactivity --> psychotic Sx --> confusion
Peaks 2-5 days after last drink |
|
periventricular hemorrhage
necrosis of mamillary bodies |
thiamine deficiency (Wernicke-Korsakoff)
|
|
Haloperidol + "azines"
(Chlorpromazine, trifluoperazine, fluphenazine, thioridazine) How do they work? |
typical antipsychotics
(neuroleptics) block D2 receptors |
|
haloperidol
trifluoroperazine fluphenazine |
high potency antipsychotics --> neurologic side effects
|
|
chlorpromazine
thioridazine |
low potency antipsychotics -->
non-neurologic side effects chlorpromazine: corneal deposits thioridazine: reTinal deposits |
|
Treatment for:
rigidity, myoglobinuria, autonomic instability, hyperpyrexia (>106 F) |
neuroleptic malignant syndrome
- dantrolene - bromocriptine |
|
In what order do extrapyramidal side effects arise from typical antipsychotics?
|
4 hours - acute dystonia
4 days - akinesia (Parkinsonism) 4 weeks - akathisia 4 months - tardive dyskinesia |
|
olanzapine
clozapine risperidone aripiprazole ziprasidone How do they work? |
atypical antipsychotics
Block 5-HT, alpha, H1, and D2 receptors |
|
hypothyroidism
polyruria heart block sedation edema teratogenic |
Lithium side effects
|
|
buspirone
How does it work? |
5-HT 1A receptor agonist
|
|
Imipramine
Amitriptyline Despiramine Nortryptiline Cloipramine Doxepin Amoxapine How do they work? |
tricyclic antidepressants
block NE and 5-HT reuptake |
|
fluoxetine
paroxetine citalopram sertraline How do they work? |
SSRIs
Inhibit serotonin reuptake |
|
Treatment for:
hyperthermia, muscle rigidity, CV collapse, flushing, diarrhea, seizures |
serotonin syndrome
- cyproheptadine (5-HT antagonist) |
|
venlafaxine
duloxetine How do they work? |
SNRIs
Inhibit serotonin and NE reuptake |
|
phenelzine
tranylcypromine isocarboxazid selegiline How do they work |
MAOIs
Increased levels of amine NTs |
|
hypertensive crisis
|
MAOI + B block or high tyramine food
|
|
priapism
|
trazodone
|
|
treatment for depression with insomnia
|
Mirtazapine
|