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13 Cards in this Set
- Front
- Back
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What is the prevalence of schizophrenia in the general population?
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1%
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What is the lifetime suicide rate for schizophrenia?
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10-15%
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When is the onset of schizophrenia?
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Most often, onset is adolescence or early adulthood.
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What is a prodrome?
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Weeks to months of gradual deterioration, social withdrawal, anxious bewilderment, self neglect, loss of motivation, and change in personality (judgment and behavior) before schizophrenics get florid psychotic symptoms.
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What are the cognitive defects in schizophrenia?
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Patients test as "brain damaged" on generalized neuropsychological batteries. Marked problems with conceptual tasks and shifting attention or cognitive "set". The Wisconsin Card Sort Test, a test of abstract reasoning and problem solving, is impaired in schizophrenia.
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What are the hallucinations like in schizophrenia?
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Generally auditory, persecutory, "command", commenting on behavior or echoing thoughts.
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What are the delusions like in schizophrenia?
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Can be paranoid and persecutory; generally bizarre and implausible.
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What are the thought disorder aspects of schizophrenia?
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Can include incoherence, neologisms, illogical thinking, loosening of associations, poverty of content, idiosyncratic word usage, clang associations, concreteness, and overinclusion.
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What are the DSM-IV criteria of schizophrenia?
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Two or more of the following for the greater part of the month (delusions, hallucinations, disorganized speech, grossly disorganized or catatonic behavior, and negative symptoms), social/occupational dysfunction, duration of at least 6 months, affective disorders and medical condition ruled out. Prodrome, positive, or negative symptoms present.
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Oxygenated Blood ENTER fetus (UMBILICAL VEIN) via ?????? INTO the IVC
(to bypass the hepatic circulation) |
Ductus venosus ( O2 blood Umbilical V -> IVC)
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What is the concordance for dizygotic twins for schizophrenia? Monozygotic twins?
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Dizygotic - 10-12% (same as siblings)
Monozygotic - 50-60% |
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PET with radio-labeled neuroleptics show increases in what kind of receptors in patients with schizophrenia?
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D2
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What brain regions are implicated in schizophrenia?
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Temporolimbic and dorso-lateral pre-frontal cortex
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