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17 Cards in this Set
- Front
- Back
schizophrenia: age of onset? |
men: 18-25 y/o women: 25-35 y/o |
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mechanism of "atypical" antipsychotics? |
serotonin & dopamine antagonists |
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major ADR of clozapine? |
agranulocytosis |
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mechanism of "typical" antipsychotics? |
dopamine antagonists |
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1st or 2nd gen antipsychotics: which is better for decreasing delusions in schizophrenia? |
1st gen (good for positive S/Sx) (e.g. haldol, chlorpromazine, thioridazine, loxapine, fluphenazine) |
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1st or 2nd gen antipsychotics: which is better for decreasing blunted affect/withdrawal in schizophrenia? |
2nd gen (good for negative S/Sx) (e.g. risperidone, paliperidone, asenapine, olanzipine, aripiprazole, ziprasidone, quetiapine) |
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how long must a pt be on an antipsychotic before you can conclude unresponsive? |
4 - 6 weeks |
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Rx for schizophrenia resistant to first-line antipsychotic? |
try combo antipsychotic + another drug (e.g. carbamazepine, valproate, lithium, benzos) |
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side effects more likely to be seen w/ typical neuroleptics? |
extrapyramidal Sx, parkinsonian-like Sx, neuroleptic malignant syndrome, tardive dyskinesia |
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pt meets criteria for both a depressive/manic/mixed episode & schizophrenia - Dx? |
schizoaffective disorder (mix of psychotic & mood Sx) |
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how is schizoaffective different from mood disorder w/ psychotic features? |
in schizoaffective, pt will have periods of delusions/hallucinations WITHOUT mood S/Sx (criteria = x2 weeks) |
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which has a better prognosis, schizophrenia or schizoaffective disorder? |
schizoaffective disorder |
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Tx schizoaffective disorder |
2nd gen antipsychotic (e.g. paliperidone) +/- mood stabilizer (lithium, valproate) or antidepressant |
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pt has nonbizarre delusions x 1+ month. Dx? |
delusional disorder (e.g. erotomanic, jealousy, persecutory) |
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Dx brief psychotic disorder? |
S/Sx for at least 1 day but <1 mo & pt returns to premorbid level of functioning commonly after a catastrophic event |
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Dx schizophreniform disorder? |
schizophrenic S/Sx for only 1-6 months |
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Dx of schizophrenia-related disorders over time? |
<1 mo: brief psychotic disorder 1 mo - 6 mo: schizophreniform >6 mo: schizophrenia |