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54 Cards in this Set

  • Front
  • Back

MDD criteria

5 of the following (but at least 1 of deoressed mood and anhedonia) for a 2 week period
Sleep
Interest
Guilt
Energy
Concentration
Appetite
Psychomotor
Suicidality

Minic episode symptoms

abnormally and persistently
elevated, expansive OR irritable
1 week (manic monoweek)
impairment
at least three of:
Distractibility
Insomnia
Grandiosity
Flight of ideas
Activity goal directed/agitation
Speech pressured
Thoughtlessness

Hypomanic criteria
4 days
3 DIGFASTS
no marked impairment
Depression or mania? which results from...

hyperthyroidism
mania
Depression or mania? which results from...
antihypertensives
depression
Depression or mania? which results from...
steroids
both
Depression or mania? which results from...
levodopa
both
Depression or mania? which results from...
HIV
mania
Depression or mania? which results from...
MS
mania
Depression or mania? which results from...
carcinoid
depression
Depression or mania? which results from...
lupus
depression
Depression or mania? which results from...
anticonvulsants
depression
Depression or mania? which results from...
diuretics
depression
Depression or mania? which results from...
sulfonamides
depression
Depression or mania? which results from...
stimulant withdrawal
depression
response to lithium in mixed episodes
reduced
MDD criteria
at least one MDE with anhedonia
no history of manic or hypomanic
triad for seasonal affective disorder
irritability
carb drawing
hypersomnia
MDD concordance for 1st degree, twins
1st degree - 2-3x more likely
dizygote - 10-25%
monozygote - 50%
lifetime prevalence of MDD
15%
% of patients hospitalized for MDE that will eventually suicide
15%
autonomic instability
hyperthermia
seizures
(possible coma/death)
serotonin syndrome
TCA side effects
sedation
weight gain
orthostatic hypoTN
anticholinergics
prolonged QTc
ause of serotonin syndrome
MAOIs used with SSRIs
MAOI side efects
- orthostatic hypotension
- hypertensive crisis
- serotononin syndrome with SSRIs
adjuvants to make nonresponders respond to antidepressants
T3, T4, lithium, L-tryptophan
indications for ECT
unresponsive to pharm
can't tolerate pharm
rapid reduction needed (suicidality)
drugs in ECT
atripine
anesthesia
muscle relaxant
ECT side effect
retrograde amnesia, better in 6 months
drugs for atypical depression
MAOIs
types of MDD
melancholic
atypical
catatonic
psychotic
atypical depression
hypersomnia
hyperphagia
reactive mood
leaden paralysis
hypersensitivity to rejection
rx for catatonic depression
antidepressants and antiPSYCHOTICS

antipsycatatonics
manic episode without a depressive episode?
still BP I
1 manic episode
BP 1
lifetime prevalence of BPD
1%
concordance rates for BPD
1st degree: 8-18x
dizygotes 5-25%
monozygotes 75%
Prognosis for BPD
worse than for depression.
50-60% on lithium get improvement
rx for rapid cyclers with BPD
anticonvulsants
rx for mixed episode BPD
anticonvulsants
antipsychotic used for BPD
olanzapine
ECT for mania?
yes, but takes more than the 8 treatments usually needed for depression
rapid cycling =
four or more episodes in 1 year
BPII criteria
at least 1 MDE
at least one hypOmanic episode
no hypERmanic episodes
tx for BPII
same as for BPI
Criteria for Dysthymia
2Ds, 2years, 2 criteria, 2 months

depressed mood
most of most days
at least 1 years (1 year in kids)
2 of CHASES
no relapses more than 2 mos
no MDE
symptoms in dysthymia
CHASES
Concentration/decision trouble
Hopelessness
Appetitie up or down
Sleep up or down
Energy low, fatigue
Self esteem low
double depression
MDD with dysthymia in between
can dysthymia have psychotic features?
no
tx for dysthmia
Cognitive therapy
insight-oriented psychotherapy
concurrent SSRI, TCA, MAOI
Cyclothymia criteria
numerous periods of hypomani and periods of depressive symptoms
2 years
2 months
no MDE or manic episode
cyclothymia can coexist with
Borderline Personality Disorder
MF for cyclothymia
M=F
episodes of depressive symptoms not meeting criteria for MDE

euthymic periods also seen
Minor Depressive disorder