Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
78 Cards in this Set
- Front
- Back
|
two categories of disordered thought
|
thought content
thought process |
|
|
false belief that one is guilty or resonsible for something
|
delusions of guilt
|
|
|
common cause of olfactory hallucinations
|
epilepsy aura
|
|
|
illusion
|
misinterpretation of an existing sensory stimulus
|
|
|
mistaking a shadow for a cat
|
illusion
|
|
|
unawarenss of where one's mind and body and those of others begin
|
loss of ego boundaries
|
|
|
differential for psychosis
|
secondary to GMC
substance induced delirium/dementia BPD MDD with psychotic Brief psychotic schizo schiphreniform SAD delusional disorder |
|
|
CNS diseases associated with psychosis
|
cv disease
MS neoplasm Parkinson's Huntington's temporal lobe eliplepsy encephalitis prio disease |
|
|
endocrinopathies associated with psychosis
|
Addison's/Cushing's
hyper/hypothyroidism hyper/hypo calcemia hypo pituitary |
|
|
vitamin deficiencies associated with psychosis
|
B12
folate niacin |
|
|
connective tissue diseases associated with psychosis
|
lupus
temporal arteritis |
|
|
metabolic disorder associated with psychosis
|
porphyria
|
|
|
DSM IV criteria for psychotic d/o secondary to GMC
|
prominent hallucinations or delusions
don't occur only during delirium evidence for medical cause PED |
|
|
DSM criteria for psychosis secondary to medication or substance use
|
prominent halllucinations or delusions
not only during delirium evidence not better accounted for by non-substance caused Hallucination DENS |
|
|
time criterion for schizophrenia
|
6 months
|
|
|
three stages of schizophrenia
|
prodromal
psychotic residual |
|
|
5 As of schizophrenia
|
Anhedonia
Affect flat Alogia (poverty of speech) Avolition/apathy Attention poor |
|
|
DSM criteria fo schizophrenia
|
2 or more of
- delusions - hallucinations - disorganized speech - grossly disorganized or catatonic behavior - negative symtpoms impairment 6 months not due to med, neuro, substance |
|
|
subtypes of schizophrenia
|
paranoid
disorganized catatonic undifferentiated residual |
|
|
criteria for paranoid type of schizophrenia
|
preoccupation with one or more delusions OR frequent AH
no predominance of - disorganized speech/behavior - catatonic behavior - inappropriate affect |
|
|
criteria for disorganized type of schizophrenia
|
disorganized speech
disorganized behavior flat or inappropriate affect DID it disorganizedly |
|
|
criteria for catatonic type of schizophrenia
|
2 of:
- motor immobility - excessive purposeless motor activity - extreme negativism/mutism - peculiar voluntary movements or posturing - echolalia or echopraxia PIN EveryMovement |
|
|
lifetime prevalence of schizophrenia
|
1%
|
|
|
monozygotic twin concordance for schizophrenia
|
50%
|
|
|
repeating words or phrases
|
echolalia
|
|
|
mimicing behavior
|
echopraxia
|
|
|
neurobiology of schizophrenia
|
increased dopamine activity in
- prefrontal cotex - mesolimbic system |
|
|
brain pathway responsible for negative symptoms of schizophrenia
|
prefrontal cortical
|
|
|
brain pathway responsible for positive symptoms of schizophrenia
|
mesolimbic
|
|
|
dopamine pathway affected by neuroleptics
|
tuberoinfundibular
nigrostriatal |
|
|
pathway related to EPS of schizophrenia treatment
|
nigrostriatal
|
|
|
pathway related to hyperprolactinemia of schizophrenia treatment
|
tuberoinfundibular
|
|
|
NT abnormalities in schizophrenia
|
dopamine
serotonin NE GABA |
|
|
signs of schizophrenia on CT
|
enlargement of ventricles
diffuse cortical atrophy |
|
|
antipsychotics that antagonize serotonin
|
risperidone
clozapine |
|
|
assocations with better prognosis for schizophrenics
|
later onset
social support positive symtpoms mood symptoms acute onset female sex few relapses good premorbid functioning |
|
|
typical neuroleptics
|
chlorpromazine
thioridazine trifluoperazine haloperidol |
|
|
action of typical neuroleptics
|
D2 antagonists
|
|
|
type of symptoms that typicals best treat
|
positive vs. negative
|
|
|
main side effects of typical neuroletics
|
EPS
neuroleptic malignant syndrome TD |
|
|
atypical neuroleptics
|
risperidone
clozapine olanzapine quetiapine aripiprazole ziprosidone |
|
|
action of atypicals
|
antagonisis D2 and 5HT2
|
|
|
spasms of face, neck tongue
|
dystonia
|
|
|
resting tremor, rigidity, bradyinesia
|
parkinsonism
|
|
|
feeling of restlessness
|
akathisia
|
|
|
EPS
|
dystonia
parkinsonism akathisia outside of the pyramid is a PAD |
|
|
anticholinergic symptoms
|
dry mouth
constipation blurred vision |
|
|
darting or writhing movements of face, tongue, head
|
TD
|
|
|
treatment for TD
|
discontinue rx
substitute atypical neuroleptic benzos, beta blockers, cholinomimentics in short term |
|
|
treatment for EPS
|
benztropine
amantadine benzodiazepines |
|
|
confusion, high fever, elevated BP, tachy, rigidity, sweating, elevated CPK
|
neuroleptic malignant syndrome
|
|
|
elevated CPK
|
neuroleptic malignant syndrome
|
|
|
lead pipe rigidity
|
neuroleptic malignant syndrome
|
|
|
high potency neuroleptics
|
haloperidol
trifluoperazine |
|
|
low potency neuroleptics
|
chlorpromazine
thioridazine |
|
|
type of antipsychotics associated with neuroleptic malignant syndrome
|
high potency
- haloperidol - trifluoperazine |
|
|
rx associated with agranulocytosis
|
clozapine (so weekly blood draws!)
|
|
|
rx that can cause irreversible retinal pigmentation at high doses
|
thioridazine
|
|
|
rx that can cause deposits in lens and cornea
|
chlorpromazine
|
|
|
quirk of clozapine treatment
|
weekly blood draws for agranulocytosis
|
|
|
time criterion for schizophreniform
|
1-6 months
|
|
|
mortality rate of neuroleptic malignant syndrome
|
20%
|
|
|
% of patients with schizophreniform ending up with SAD/SD
|
66%
|
|
|
Treatment for schizophreniform
|
hospitalization
3-6 mos of antipsychotics supportive psychotherapy |
|
|
criteria for SAD
|
criteria for MDD, manic or mixed episode AND schizophrenia
delusions or hallucinations for 2 weeks in absence of mood disorder mood symtpoms present for substantial portion of psychotic illness GMC/rx not cause |
|
|
criteria for brief psychotic disorder
|
1 day to 1 month
not due to GMC/Rx |
|
|
nonbizarre dellusions
|
beliefs that might occur in real life but are not currently true (e.g., having a disease)
|
|
|
delusions that revolve around love
|
erotomanic
|
|
|
phsycial delusions
|
somatic
|
|
|
delusions of unfaithfulness
|
jealous type
|
|
|
criteria for delusional disorder
|
nonbizarre, fixed delusions for at least 1 month
not meeting criteria for schizophrenia no significant functional impairment |
|
|
folie a deux
|
shared psychotic disorder
|
|
|
paranoid
odd or magical beliefs eccentric lack of friends social anxiety |
schizotypal personality disorder
|
|
|
withdrawn
lack of enjoyment from social interactions emotionally constricted |
schizoid personality disorder
|
|
|
patient believes that his penis is shrinking and will disappear, causing death
|
Koro, seen in Asia
|
|
|
sudden unprovoked outbursts of violence of which the person has no recollection
|
Amok, seen in Malaysia, SE Asia
|
|
|
headache
fatigue visual distrubances in male students |
brain fag, seen in Africa
|
|
|
% of shared pschotic disorder patients that recover after separation
|
40%
|
