Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
20 Cards in this Set
- Front
- Back
|
Definition: Pharmacokinetics
|
Study of the movement of drugs through the body
|
|
|
Different routes of drug administration
|
Orally. Rectally. Parentally (sringe/needle). Inhaled. Absorption- skin & mucous membrane.
|
|
|
Drug administration- fastest and slowest
|
Fastest- Inhaling, intravenous, parentally
Slowest- Absorption, rectal, orally. |
|
|
circulatory system, how blood circulates around the body.
|
Deoxygenated blood enters right Atrium, right Ventricle, then Lungs, oxygenated blood then goes to left Atrium, left Ventricle, goes to aorta then the brain and rest of body.
|
|
|
Organs involved in metabolism and excretion
|
Liver- metabolizes.. Kidneys, stomach, intestines, lungs, sweat, breast milk.
|
|
|
How many half-lives to reach 25% concentration in body?
|
2 (goes from 100, half is 50, half is 25.. 2 half lifes)
|
|
|
Parts involved in Central Nervous System
|
Brain & Spinal Cord.
|
|
|
Peripheral Nervous System
|
Nerves that connect the CNS to the rest of the body.
|
|
|
Sympathetic Nervous System
|
Stress. Fight or Flight. Survival skills. Stimulates body.
|
|
|
Parasympthetic Nervous System
|
Peace. Rest & Digest. Relaxes us, slows heart.
|
|
|
4 basic functions of the lobes in brain
|
Occiptal- vision, sensory
Temporal- store of visual objects. Parietal- Finding here things are, sptial objects. Frontal- Problem solving, planning, rational thinking. |
|
|
Functions of brain regions. Hippocampus, amygdala, thalamus, reticular formation, hypothalamus.
|
Hippocampus- memories
Amygdala- Emotions Thalamus- Organization Reticular formation- wakes brain up. Hypothalamus- Fighting, fleeing, feeding, fucking. |
|
|
Main neurotransmitters & where they are made.
ACH, glutamate, GABA, dopamine, norepherine, serotonin. |
ACH- 3 places
Glutamate- ALL over GABA- ALL over Dopamine- 2 places Norepinephreine- 1 place Seratonin- 1 place |
|
|
Drugs & N.T.'s.. ACH, Glutamate, GABA, dopamine
|
ACH- curare (antagonist)
-Botox- antagonist -nerve gas- agonist Glutamate- MSG- agonist - PCP- antagonist -CO- agonist GABA (inhibitory)- antianxiety- agonists Dopamine- MAO & COMT |
|
|
Metabolic tolerance
|
liver breaks down drug faster as more is administered
|
|
|
Pharmacodynamic tolerance
|
brain receptors decrease or less stimulated over time
|
|
|
Behavioral conditioning
|
conditioning to a context. location of where youre drinking affects high.
|
|
|
Drug interactons-
Additive Interactions |
2 drugs stimulate you and add together.
Drug A (5) + drug b (5)= 10 |
|
|
Hyperadditive interactions
|
Sum is way more than additive of 2 drugs. 5 + 15 = 40. High
|
|
|
Antagonism
|
1 stimulant, 1 supressant. Counteract each other. lands you in between
|
