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36 Cards in this Set

  • Front
  • Back

Oocysts on acid fast stain

Cryptosporidium, watery diarrhea, worse in AIDS

Tx for water tumbling double nuclei trophozoites / cysts in stool

Metronidazole (giardia)

Liver abscess cause (anchovy paste exudate)

Entamoeba histolytica

Tx for trophozoites with RBCs inside

Metronidazole (entamoeba histolytica)

Cysts with multiple nuclei

Entamoeba histolytica

Cannot form cysts, motile trophozoites on strawberry cervix

Trichomonas, tx with metronidazole

Tx toxo?

sulfadiazine + pyrimethamine

Naegleria tx and mech of infexn

Amphotericin B // through cribriform plate

Trypanosoma brucei tx blood vs cns involvement

Suramin, melarsoprol

Sx of leishmaniasis

Spiking fevers, HSM, pancytopenia

Tx for leishmaniasis

Amphotericin B // sodium stibogluconate tx ulcerating papules that are slow to heal

Primaquine?

used for dormant vivax and ovale infexns --> targets hepatocellular dormancy

Banana shaped gametocyte

P. falciparum (only one for cerebral malaria)

Tx for resistant malaria (Africa)

mefloquine, atovaquone/proguanil

Maltese cross tx?

Babesiosis, tx with Atovaquone+Azithromycin // Quinine +Clindamycin

Malaria form that ruptures host cells

merozoite - release = fever

Malaria form that replicates intracellularly

Schizont

Malaria form injected from mosquito

Sporozoite

Ascaris lumbricoides in the lungs

Loeffler eosinophilic pneumonitis

Muscle cysts / larvae

Trichinella spiralis, from game animals

Skin invasion

Strongyloides, necator, ancylostoma (SANd)

Worm tx + MOA

Bendazoles (decrease glucose uptake) and pyrantel pamoate (nicotinic agonist = contraction/paralysis = ejection of worm)

ingesting eggs of taenia solium

cysticercosis - need to tx with Praziquantel, bendazole + dexamethasone (prevents cns symptom worsening from dying larvae)

Raw fish worm

diphyllobothrium latum = B12 deficieincy, tx with Praziquantel

Cysts in liver

Echinococcus granulosus = need to kill before removing surgically

schistosoma infectious unit

cercaria from snails --> penetrate skin

Schistosoma mansoni vs S hematobium

mesenteric vessels,caribbean vs. lower urinary tract + Egypt (leads to squamous cell bladder carcinoma)

Collateral damage from Schistosoma

eggs embolize in portal system and cause Portal HTN + Splenomegaly

Uncooked crab meat

Paragonimus westermani "lung fluke" chronic bronchitis and hemoptysis

Pigmented gallstones + cholangiocarcinoma

Clonorchis sinensis = liver fluke, undercooked fish

Gancyclovir tox

marrow suppression, renal failure

Zidivudine tox

marrow suppression / neutropenia w gancyclovir

LoaLoa / Wuchereria tx

diethylcarbamazine

Praziquantel

treats: schistosoma, paragonimus westermani , clonorchis

MOA Chloroquine

blocks detoxification of heme into hemozoin = heme accumulates and is toxic

artemether / artesunate MOA and use

block ATPase in falciparum