Principles I: Exam Ii: Blood Transfusions And Blood Products

Front 1

type and screen takes how long

Back 1

15 - 45 minutes

Front 2

type and cross is what

Back 2

mixing of donor blood and recipient blood looking for incompatability - clumping

Front 3

type and cross takes how long

Back 3

45 minutes

Front 4

type and screen determines

Back 4

ABO, Rh, Antibody screen

Front 5

how many donations demonstrate unexpected antibodies

Back 5

4 in 1000

Front 6

if a pt demonstrates rare antibodies in the blood, can hold up getting compatible blood for

Back 6

as much as a day

Front 7

Blood type A has what antibodies

Back 7

B

Front 8

Blood type B has what antibodies

Back 8

A

Front 9

blood type AB has what antibodies

Back 9

no antibodies

Front 10

blood type O has what antibodies

Back 10

A and B antibodies

Front 11

the universal donor is blood type

Back 11

O

Front 12

the universal acceptor is blood type

Back 12

AB

Front 13

the universal plasma donor is blood type

Back 13

AB

Front 14

if you have blood type AB, then you can get plasma types

Back 14

AB

Front 15

if you have blood type A, then you can get plasma types

Back 15

A or AB

Front 16

if you have blood type B, then you can get plasma types

Back 16

B or AB

Front 17

if you have blood type O, then you can get plasma types

Back 17

any blood type

Front 18

what is contained in whole blood

Back 18

everything - plasma, clotting factors, white blood cells, red blood cells, platelets

Front 19

who uses whole blood

Back 19

the military

Front 20

why do we not use whole blood

Back 20

optimizes resources
makes more $$$

Front 21

one draw back of whole blood

Back 21

requires more cross matching

Front 22

each unit of PRBCs contains

Back 22

200 ml RBC
100 ml additives
30 ml plasma

Front 23

PRBC additives are

Back 23

CPDA, sodium chloride, mannitol

Front 24

CPDA stands for

Back 24

citrate phosphate dextrose adenosine

Front 25

how much volume in a unit of PRBC

Back 25

300 - 350ml

Front 26

problems with PRBC

Back 26

minimal coag factors, platelet lose function

Front 27

PRBCs are stored

Back 27

1 - 4 degrees Celsius, shelf life 42 days

Front 28

Hct of PRBC is

Back 28

70%

Front 29

replace blood loss with PRBC

Back 29

1:1

Front 30

1 unit PRBC will increase Hgb and Hct

Back 30

by 1 gm/dl and 3% in a 70 Kg adult

Front 31

when transfusing blood in a child, calculate improving Hgb by

Back 31

10 ml/kg will increase Hgb by 3 gm/dl (Hct 10%)
3 ml/kg will increase Hgb by 1 gm/dl (Hct 3%)

Front 32

what size filter do you use with blood

Back 32

170 micron filter

Front 33

how many units of PRBC do you give to get an old lady's Hgb of 7 up to 10

Back 33

3 units

Front 34

how much blood would you give a child with a Hgb of 4

Back 34

10 ml/kg to increase Hgb by 3 g/dl

Front 35

FFP contains

Back 35

all plasma proteins including clotting factors except factors V and VIII which are washed out more easily

Front 36

use FFP for some examples

Back 36

correction of coagulopathies (liver disease, coumadin reversal, massive blood transfusions, antithrombin three deficiency)

Front 37

FFP carries infection risk

Back 37

same as that of PRBCs

Front 38

dose of FFP to increase clotting factors

Back 38

10 - 15 ml/kg increases clotting factors by 30%

Front 39

dose of FFP to reverse coumadin

Back 39

5 - 8 ml/kg

Front 40

platelets counts below what are associated with increased blood loss

Back 40

50,000

Front 41

transfused platelets survive

Back 41

1 - 7 days

Front 42

platelets contain how much plasma

Back 42

70 ml per unit

Front 43

1 unit of platelets increases platelet count by as much as

Back 43

5,000 - 10,000

Front 44

dosing of platelets in kids

Back 44

10 ml/kg for infants and kids up to 30 kg

Front 45

1 unit platelets for every 10 kg in children will increase platelet count by

Back 45

50,000

Front 46

spontaneous bleeding occurs at what platelet count

Back 46

20,000

Front 47

multiple blood transfusions affect platelets because

Back 47

multiple transfusion lead to antibody formation that destroy platelets

Front 48

reduce risk of platelet destruction with blood transfusion by

Back 48

ABO compatibility

Front 49

platelet destruction with multiple transfusions is as high as

Back 49

50%

Front 50

platelet contamination is more common because

Back 50

pooled product kept at room temperature

Front 51

platelets are stored

Back 51

at room temperature under continuous agitation

Front 52

platelet units may not be

Back 52

compatible (with each other)

Front 53

cryoprecipitate contains

Back 53

I, VIII, XIII, fibrinogen, and vWF

Front 54

cryoprecipitate is used for

Back 54

low fibrinogen levels, factor VIII deficiencies (hemophilia A) and vonWillebrand's

Front 55

normal fibrinogen levels are

Back 55

200 - 400 mg/dl

Front 56

transfusion trigger for fibrinogen

Back 56

less than 100 mg/dl

Front 57

cryoprecipitate dosing

Back 57

1 unit/10kg in children or adults will increase fibrinogen levels by 50 - 60 mg/dl