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26 Cards in this Set

  • Front
  • Back
Spread of Infection
Source of Pathogens
Susceptible Host
Route of Transmission
Infection Risk Categories
Critical
Semi-critical
Non-Critical
Critical
Devices introduced into blood stream requires sterilization
Semi-critical
Devices contacting mucous membranes require high level disinfection
Non-Critical
Devices that contact only the skin or not at all required either detergent washing or low to intermediate disinfection
Equipment Processing
Removes Dirt and Organic Material
Steps
Disassemble Equipment
Wash With Germacide Detergent
Rinse Well and Dry
Residual Water Dilutes or Alters Subsequent Disinfection
Changes pH of Disinfectants
Creates Ethylene Glycol (Antifreeze) When Combined with Ethylene Oxide Gas
Prevent Recontamination
Pasteurization
Moist Heat at Temperatures Below Boiling
Coagulates Cell Proteins
Kills All Vegetative Bacteria, Most Viruses Including HIV
Does Not Kill Spores
Requires Immersion of Equipment
Problem is With Recontamination
Chemical Disinfection – Low Level
Kills Most Bacteria and Some Viruses
Does Not Kill Resistant Microorganisms Like Tuberculosis and Spores
Acetic Acid – White Vinegar (Good for Disinfection of Home-Care Equipment)
Quaternary Ammonium Compounds
Examples - Roccal, Lysoquat, TKO, and Zephiran
Hospital Use is Mainly for Surface Areas
Chemical Disinfection – Intermediate Level
Kills All Vegetative Bacteria Including Tuberculosis
Variable Activity Against Spores and Some Viruses
Alcohols
70% Ethyl Alcohol and 90% Isopropyl Alcohol
Inactivated by Protein
Can Damage Rubber/Plastics
Good for Surface Disinfection of Medicine Vial Tops/Stethoscopes/Resuscitation Mannequins
Phenolics
Remain Effective On Surfaces Long After Application
Irritating, so Not Used on Items Exposed to Skin
Iodophors
Used in Low Concentrations as Antiseptics
Chemical Disinfection – High Level
Kills All Microorganisms Except Spores
Alkaline Glutaraldehyde
Requires Immersion
Requires Immersion
Kills Vegetative Bacteria, Tuberculosis, Fungi and Viruses in 10 Minutes
Kills Common Spores (Sterilizes) in 3 Hours
Must Be Activates and is Active for 28 Days
Exposure Leads to Inflammation (Vapors Cause Epistaxis, Rhinitis, Asthma)
Rinsing is Required or Tissue Inflammation Can Result
Chemical Disinfection – High Level
.Hydrogen Peroxide
.Sodium Hypochlorite (Household Bleach)
.Paracetic Acid
Hydrogen Peroxide
Used as Wound Antiseptic
Bactericidal, Fungicidal, Virucidal in 10 Minutes at Room Temperature
Recommended to clean up blood spills
Kills Spores in 6 Hours if Heated
Sodium Hypochlorite (Household Bleach)
Fast Acting, Inexpensive
Kills Vegetative Bacteria, Most Spores and Tuberculosis in 10 Minutes
Paracetic Acid
Highly Effective but is Unstable and Corrosive to Some Metals
Sterilization – Physical
.Incineration (Burning
.Dry Heat (Oven)
.Boiling Water (100OC)
Incineration (Burning)
Destroys the Item
Dry Heat (Oven)
1-2 Hours at 160-180OC (320-356OF)
Good for Glass and Metal
Boiling Water (100OC)
Kills Vegetative Bacteria and Viruses in 30 Minutes
Some Spores are Resistant
If Water Boils Away and More is Added – Temperature Drops
Water boils at Lower Temperature at Higher Altitudes
Good for Home Use
Sterilization – Physical
Autoclaving – Steam Under Pressure
Gay Lussac’s Gas Law
In a Closed System, Increasing Pressure will Increase Temperature
Pressure Cooker is Similar
The Higher the Pressure and Temperature, the Faster the Sterilization (15 psi/121OC Will Sterilize in 15 Minutes)
Equipment is Wrapped in Cloth or Paper for Steam to Penetrate. Packaging Prevents Recontamination After Sterilization
Most Respiratory Therapy Equipment is Damaged by Autoclaving
Autoclaving
Steam Under Pressure
Sterilization – Physical
Ionizing Radiation
Ionizing Radiation
X-Rays and Gamma Rays – Used for Commercial Sterilization of Disposable Supplies and Equipment
Ultraviolet Light – Used for Decontaminating Air Circulating into Operating Rooms, Nurseries, Isolation Wards, Bacteriologic Labs
Sterilization – Chemical Ethylene Oxide Gas (EtO)
Most Respiratory Therapy Equipment is Sterilized by EtO
Potent Sterilizing Agent Effective at Room Temperature and Penetrates Packaging
Sterilization – Chemical Ethylene Oxide Gas (EtO)
Problems
Exposure to Gas is Toxic (Airway Inflammation, Nausea, Diarrhea, Headache, Dizziness, Convulsions)
Gas is Carcinogenic, Mutagenic, and Teratogenic)
Combined with Water, EtO Forms Ethylene Glycol (Antifreeze)
Is Explosive at Concentrations higher than 3%
Sterilization – Chemical Ethylene Oxide Gas (EtO)
Aeration of Processed Equipment Allows For Removal of Residual EtO From Porous Materials After Sterilization
Gas and Aeration Chambers are Vented To the Outside
Chemical and Biologic Indicator Strips Assure Monitoring of Exposure