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32 Cards in this Set
- Front
- Back
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what is required to meet the DSM IV's definition of a major depressive episode?
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(5) or more of SIGECAPS for 2 wks
must include either: - depressed mood - anhedonia (interest/pleasure loss) |
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how is HSV diagnosed? (3)
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viral isolation
- sensitive w/in 72 hrs of onset antibody testing (96% sensitivity) - seroconvertion ~3months Tzanck smear (50% sensitivity) - multinucleated giant cells |
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what is the primary treatment for herpes?
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acyclovir
(inhibitor of viral DNA polymerase) |
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what are the characteristics of a chancre secondary to syphilis (treponema pallidum)?
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painless
firm raised edges |
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what causes syphilis?
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treponema pallidum
- a gram-negative spirochaete bacterium - too small for gram stains - dark field microscopy/immunofluorescence to visualize |
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how do you diagnose syphilis?
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nontreponemal tests: RPR/VRDL
- (+) 1-3 wks after chancre - usually reverts to (-) treponemal tests: FTA/MHA - (+) for life - darkfield microscopy |
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what's the timing/symptoms of primary syphilis?
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10-90 days
- chancre -lymphadenopathy |
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what's the timing/symptoms of secondary syphilis?
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6wks-6mo
rash nonspecific condyloma lata (white spots on palms/soles) |
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what's the timing/symptoms of latent syphilis?
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>6mo
gummas (granulomas) neuro-syphillis aortic insufficiency |
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what's the timing/symptoms of neuro-syphilis?
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months-years
general paresis dementia tabes dorsalis (shuffling gait) AR pupil (accomodates, doesn't react) |
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how do you treat syphilis?
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benzathine PCN (IM)
(alt: tetra, doxy, erythro, ceftriaxone, azithro) - follow titer at 6 and 12 mo - if latnet/tertiary (>1 yr), give qweek x 3 |
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what are the characteristics of a chancroid chancre?
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painful
irregular undermined edge excavated yellow/gray base |
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what causes a chancroid?
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haemophilus ducreyi
(Gram-negative coccobacillus ) - most common cause of genital ulceration worldwide |
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how do you diagnose a chancroid?
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culture on selective media
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how do you txt a chancroid?
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azithromycin
or ceftriaxone |
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what is lymphogranuloma venereum?
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chlamydia trachomatis
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describe the characteristics of a chlamydia trachomatis infection
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transient primary painless ulcer (2-5 d)
enlarged suppurative nodes (1-4 wk) complicated by fistulas, ulceration |
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what is the txt of chlamydia trachomatis?
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doxycycline
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what causes granuloma inguinale (donovanosis)?
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calymmatobacterium granulomatis
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what are the characteristics of a granuloma inguinale (donovanosis) infection?
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papular lesion ulcerates into soft, red, painless granuloma which spreads
lymph nodes enlarged, not suppurative |
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how do you diagnose granuloma inguinale (donovanosis)?
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Donovan bodies on giemsa stain from lesion periphery (bipolar staining bacteria within mononuclear cells)
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how do you treat granuloma inguinale (donovanosis)?
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bactrim or doxycycline
(3 wks) |
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what are the mc low/high risk subtypes of HPV?
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low: 6 and 11
high: 16 and 18 |
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what are the 2 types of patient applied condylomata txts?
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podofilox < imiquimod
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describe the vaginitis assd with trichomonas vaginalis infection
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yellow discharge
vulvar irritation pH > 4.7 leukocytosis |
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how do you treat trichomonas?
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metronidazole (2g) PO
or metronidazole (500mg) PO x 7d |
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gram stain of gonorrhea?
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G(-) diplococcus, intracellular
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what are (3) ways to diagnose gonorrhea?
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gram stain (50%sn / 100%sp)
Thayer-Martin culture (80-90%sn) DNA probe (90%sn / 99%sp) |
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Hyperalgesia severity correlates with circulating _____ levels.
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increased sensitivity to pain correlates with estradiol levels
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what is Carnett’s test?
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used to differentiate between pelvic pain and myofascial pain
(+): pain remains with crunch (MYOFASCIAL) (-): pain less or gone with crunch (favors PELVIC) (careful—can be both) |
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how do you treat gonorrhea? (5)
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ceftriaxone
cefixime ciprofloxacin ofloxacin levofloxacin |
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how do you treat chlamydia in non-pregnant vs pregnant?
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nonpregnant:
- azithromycin - doxycycline pregnant: - erythromycin - amoxicillin (test for cure at 3 wks) |
