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132 Cards in this Set

  • Front
  • Back

What clues would let you know that abdominal pain is acute or surgical abdomen?

Acute onset


sever pain


>6 hr


rapidly worsening

What clues would let know that abdominal pain is acute or chronic onset?

ACUTE: less than few days w. progressive worsening


CHRONIC: interval of 12 weeks

What is emergent abdominal pain?

<3 hours


with fever and vomiting

What organs are anatomically located in the RUQ?

liver, gallbladder, large intestine (hepatic flexure), small intestine, part of stomac, part of pancreas, kidney, ureter

What organs are anatomically located in the LUQ?

part of stomach, pancreas, spleen, large intestine, small intestine, kidney ureter

What organs are anatomically located in the LLQ?

large intestine, small intestine, sigmoid colon, ovary, fallopian tube, 1/2 uterus, 1/2 bladder, epididymis, ureter

What organs are anatomically located in the RLQ?

appendix, large intestine, small intestine, ovary, fallopian tube, 1/2 uterus, 1/2 bladder, epididymis, ureter

If a patient describes abdominal pain as:


"burning" or "gnawing"


What is the likely cause/origin?

ulcer

If a patient describes abdominal pain as:


"colicky" "wavelike" "intermittent"


What is the likely cause/origin?

hollow tube obstruction:


bowel (with hyperperistalsis)


biliary tube


ureter

If a patient describes abdominal pain as:


"steady" "worse with cough"


"palpation" "movement/increased pressure"


What is the likely cause/origin?

peritoneal irritation

If a patient describes abdominal pain as:


"cramping"


What is the likely cause/origin?

altered bowel motility


metabolic disturbances

If a patient describes abdominal pain as:


"cyclic" "related to menses"


What is the likely cause/origin?

gynecologic cause

If a patient describes abdominal pain as:


"related to meals" "abdominal angina"


What is the likely cause/origin?

vascular

If a patient describes abdominal pain as:


"tearing" "radiating to back"


What is the likely cause/origin?

dissecting aneurysm

If a patient describes abdominal pain as:


"constant aching"


What is the likely cause/origin?

distention of encapsulated structure:


liver, kidney, spleen, ovary

If a patient describes abdominal pain as:


"burning , along dermatome"


What is the likely cause/origin?

nerve irritation

What are the 3 types of abdominal pain?

visceral


parietal


referred

What are the most common diagnoses of RUQ abdominal pain?

* acute cholecystits-billiary colic (radiates to scapula)*


*acute hepatitis*




differential: hepatic abscess, hepatomegaly/CHF, perforated duodenal ulcer, acute pancreatitis, herpes zoster, MI, pleural or pulmonary (RLL pneumonia, pulmonary emboli, pleurisy)

What are the most common diagnoses of RLQ abdominal pain?

*appendicitis (begins periumbilical)*




differential: regional enteritis, leaking aneurysm, ruptured ectopic pregnancy, twisted ovarian cyst, PID, urteral calculi

What are the most common diagnoses of LUQ abdominal pain?

*gastritis*




differential: acute pancreatitis, splenic enlargement, rupture infarction, aneurysm, MI, LLL pneumonia

What are the most common diagnoses of LLQ abdominal pain?

*sigmoid diverticulitis*




differential: regional enteritis, leaking aneurysm, ruptured ectopic pregnancy, twisted ovarian cyst, ureteral calculi, incarcerated-strangulated inguinal hernia

What are key things to know about abdominal pain in older adult?

often stuble always evaluate


fever less likely


may exhibit lethargy or mental status changes

When questioning abdominal pain in females, what must be done?

Must obtain sexual history


Must do pelvic exam in all females


Consider PID


Must exclude ectopic pregnancy if child bearing age


What is the risk of appendicitis?

Inflammatory disease of wall of appendix that can cause gangrene & perforation in 24-36 hours

What are early reliable indicator symptoms that appendicitis is causing abdominal pain?

Pain begins in epigastric or periumbilical area then localizes to the RLQ


Colicky pain, becomes severe


Worse with movement

What are late reliable indicator symptoms that appendicitis is causing abdominal pain?

Nausea & vomiting


Helps to differentiate gastroenteritis


Vomiting begins before abdominal pain in gastroenteritis

What is the pathophysiology of appendicitis?

Appendices lumen becomes inflammed, obstructed--> mucosa continues to secrete fluid--> pressure increases in appendix --> mucosa ulcerates--> bacteria invade--> increased swelling & ischemia--> appendix perforates

When doing an abdominal exam for appendicitis, what are expected findings?

Localized tenderness


McBurney's point (in between navel & iliac spine)


Patient can point with one finger to pain

If peritoneal irritation is present in appendicitis, what will your exam findings be?

Rebound tenderness


Guarding


+Psoas sign


+Obturator sign

What is a positive psoas sign?

Pain with passive right leg extension


Indicates irritation of iliopsoas

What is a positive Obturator sign?

Indicates irritation of Obturator muscle


Patient lies supine with right hip knee flexed


Passive rotation of right leg


Pull right knee laterally (Hip external rotation)


Pull right knee medially (hip internal rotation)

When doing a rectal exam what are expected findings?

Tenderness


Possible mass

What is McBurney's point?

One third the distance from the anterior iliac spine to the navel


*common location of the base of the appendix where it is attached to the cecum

What are diagnostic blood work that can be done for appendicitis?

CBC w/ diff=


Leukocytosis - elevated WBC


Neutrophilia - elevated neutrophil


Bandemia - elevated # bands (young neutrophils)


Beta hCG


UA


CRP



What are diagnostic tests that may be done for appendicitis?

Ultrasound


**CT of abdomen - more accurate

What is a a small bowel obstruction?

Partial or complete obstruction of bowel lumen


-paralysis or ileus of intestinal musculature

What subjective questions to ask for small bowel obstruction, Q&A?

Q: Acute diffuse abdominal pain?


A: Intermittent, crampy pain


Q: Vomiting?


A: Relieves pain


Q: Passing flatus, last BM, H/O abd/pelvis sx (adhesions)

What are physical findings that may be present in a small bowel obstruction exam?

-distended tympanic abdomen


-high pitched tinkling bowel sounds


OR


-NO bowel sounds


-mid abdomen tenderness (guarding/ rebound)


-check umbilicus for hernia


-rectal exam (stool? Mass?)

What are diagnostics for a small bowel obstruction?

Abdomen x-ray


Upright/spine

What is the management for a small bowel obstruction?

NPO - bowel rest


NG tube for decompression


May need laparotomy

What is a perforated peptic ulcer?

16% of elderly c/o abdominal pain


Most common is free perforation

What are subjective findings in a perforated peptic ulcer?

Severe abdominal pain


-begins in epigastrium


-spreads throughout abdomen


-radiates to scapula


Vomiting


H/O: PUD, h. Pylori, chronic NSAID use


What are physical findings present with a perforated peptic ulcer?

-severe pain w. palpation in


Upper abdomen


-rigid abdomen


-fever

What is the diagnostic & treatment plan for a perforated peptic ulcer?

DX: Abd x-ray shows free air


TX: surgical consult

Who is at risk for a ruptured aortic aneurysm?

Age >65


H/O ASHD


Hypertension


Smoking

What are subjective findings of a ruptured aortic aneurysm?

C/o abdominal pain radiating to flank, low back, groin

What are objective findings for a ruptured aortic aneurysm?

Hypotension


Pulsatile mass


Aortic bruits


Absent or unequal peripheral pulses


What is the management ruptured aortic aneurysm?

Surgical consult

Anorectal complaints are similar to which other differential conditions?

*hemorrhoids (enlarged/prolapse vascular tissue in the submucosal layer of anal canal)


*anal fissure (linear cracks or tears in lining of anal canal)


*pruritis ani (itching sensation of anus and perianal skin)

What are hemorrhoids?

Enlarged or proposed vascular tissue in the submucosal layer of anal canal


*Internal or external

How are hemorrhoids developed?

A result of increased pressure applied to pelvic floor:


- pregnancy


- prolonged standing


- straining


- lifting


- constipation


- diarrhea

What distinguishes internal hemorrhoids?

Above denate line columnar epithelium

What distinguishes external hemorrhoids?

Below denate line squamous epithelium

In the clinical presentation of hemorrhoids, what are subjective complaints?

Bleeding


(Painless, bright, red blood - occurs after defecation - on toilet tissue, on stool or in toilet water)


Pruritis


Protrusion


Pain


In the clinical presentation of hemorrhoids, what are objective findings?

-internal: not palpable on rectal exam unless thrombosed


-external: thrombosed vs. not-thrombosed


Thrombosed, erythema,sensitive


Not-thrombosed, tender dark blue nodule


-severe rectal pain unusual, suggests gangrenous hemorrhoid


What is the conservative management of hemorrhoids?

High fiber diet / increased fluids


Warm water sitz baths


Topical anti-inflammatory preparations:


*hydrocortisone (anusol-HC; ProctoCream)


*hydrocortisone & pramoxine (analpram-HC; ProctoFoam-HC)

What is the management of thrombosed hemorrhoids?

Surgical Evacuation


If persistent:


-rubber band ligation


-laser coagulation


-hemorrhoidectomy

What are anal fissures and what is their cause?

Linear cracks or tears in lining of anal canal


Caused by:


Hard stool


Frequent diarrhea


Healing--> scar tissue formation & anal stenosis

What is the management of an anal fissure?

Fiber / stool softner


Sitz baths


Topical anesthetics (i.e. lidocaine gel) prior to passing stool


Topical glyceryl trinitrate (Rectiv nitroglycerin cream) causes increase blood flow and decrease sphincter pressure

What is pruritus ani and it's possible causes?

Itch-Scratch cycle


-idiopathic


-infectious (pinworm)


-improper hygiene


-secondary to systemic causes:


Diabetes, renal insufficiency, medications

What is the management of pruritus ani?

-skin care to keep clean/dry


-1% hydrocortisone topical


-antihistamine PO (i.e. atarax)

How is diarrhea classified and determined?

**Must know patient's normal stool pattern**


Frequency: >3 times/day


Volume: liquidity


Morbidity (variable): mild & self-limiting / severe & life-threatening


Acute: <2 weeks


Chronic: >1 month

What are infectious causes of diarrhea?

Age: most common <5 yr


Non-inflammatory: viruses / bacteria / parasites


Inflammatory: bacteria / parasites


Spread by:


*food & water contamination


*person to person contact


*Fecal-oral route


*animals

What are causes of non-infectious (chronic diarrhea)?

Medications


Lactose intolerance


Toxins, environmental


Endocrine disorders: thyroid, diabetes


Pernicious anemia


Irritable bowel syndrome


Inflammatory bowel syndrome


Crohn's disease


Malignancy


HIV disease


Celiac sprue


Scleroderma


Whipple's disease

When preforming an exam, what are subjective questions that should be asked?

Onset


# of diarrhea stools/day


-normal stool pattern


-occur with respect to meals/sleep


-food related reactions


Weight loss?


Abdominal pain?


Sense of incomplete evacuation?


Blood or pus or mucous of fat in stool?


Medications?


PMH:all comorbidities?


Tobacco, alcohol, illicit drug use?


Laxative abuse?

On a physical exam for a patient with diarrhea, what should be done to check hydration status?

Orthostatic VS


Weight


Mucous membranes


Skin turgor

On a physical exam for a patient with diarrhea, what should be done to check abdomen?

-distension?


-ascultate: bowel sounds, bruits, succession splash, free fluid air, ga


-palpate: pain, rigidity, rebound, guarding, masses, acites?


-dre: fecal impactation, occult blood?


-pelvic exam

Which symptoms should be present to order diagnostics for acute diarrhea?

-fever


-abdominal pain


-dehydration


-protracted nausea/vomiting


-diarrhea >1wk


-blood in stool


-immunocompromised status

What does a stool analysis look for in acute diarrhea?

-fecal leukocytes


-occult blood


-culture (bacterial)


-ova parasites (>7-10 days)


-c. difficile toxin A&B


-giardia ELISA (antigen test for giardia)

What types of radiology diagnostics can be ordered for acute diarrhea?

abdominal flat plate & upright

What are the diagnostic lab work for acute diarrhea?

CBC, Serum electrolytes, BUN, Cr

What is the treatment to replace fluid and electrolytes in acute diarrhea?

Oral


Clear liquids or rehydration solutions


Intravenous

What is the proper refeeding diet for a patient with acute diarrhea?

Avoid: high fiber, diary, fats, caffeine, alcohol


BRAT: bananas, rice, applesauce, and toast

What is the definition of chronic diarrhea?

Decrease in fecal consistency for >4 weeks


It's is classified by the etiology:


Inflammatory, osmotic, secretory, altered intestinal motility, factitious

What are the causes of inflammatory diarrhea (lasts longer than 4 weeks)?

Infectious, AIDS, eosinophilic gastroenteritis, radiation

What are the causes of osmotic diarrhea (lasting >4 wks)?

Stops with fasting


Malabsorption, lactase deficiency, chronic alcohol abuse, celiac disease, thyrotoxicosis, short gut post surgery

What are the causes of secretory diarrhea (>4 wks)?

Large volume watery diarrhea continues with fasting


Carcinoid syndrome, pancreatic adenomas

What are the causes of altered intestinal motility (>4 wks)?

Most common in clinical practice


Irritable bowel syndrome, neurologic disease, fecal impactation, diabetes

When evaluating for chronic diarrhea what causes may be excluded?

Acute diarrhea


Lactose intolerance


Previous gastric surgery or ideal resection


Parasitic infection


Medication


Systemic disease

For chronic diarrhea evaluation, what is done for a stool analysis?

Electrolytes, pH


Osmolarity


Weight/24 hr


Occult blood


Leukocytes (WBC)


Quanitive fecal fat

For chronic diarrhea, what is imaging can be done?

Barium enema, CT abdomen to r/o pancreatic


Colonscopy, sigmoidoscopy & biopsy, possible UGI or EGD

What are anti-motility agents for chronic diarrhea?

Lomotil


Immodium


Codeine


All are contraindicated in infectious diarrhea

What is the treatment for Lactose intolerance?

Lactase (Lactaid)

What is the treatment for bile salt malabsorption?

Questran

What is the treatment for colitis chronic diarrhea?

Budesonide

What is the treatment for inflammatory bowel chronic diarrhea?

Steroids


Sulfasalazine

What is the treatment for carcinoid or peptide secreting tumors chronic diarrhea?

Octreotide (Sandostatin)

What would be considered decreased frequency of bowel movements in constipation?

-difficult defecation of hard stool


-less than 3 BMs per week

Before diagnosis, onset within 6 months, which of the following are


the ROME III Criteria

-less than 3 bm/wks or hard or lumpy stool


-sensation of straining


-feeling of incomplete evacuation or anorectal obstruction


-manual maneuvers to aid defecation in more than 25% of defecation


AND


-stool stool not passed easily w/o use of medication

What are primary causes of constipation?

Prolonged total gut transit time


-(Neuromuscular dysfunction)


-decreased activity


Pelvic floor or anorectal dysfunction


-failure to empty rectum


What are secondary causes of constipation?

-ignoring urge to defecate


-inadequate fiber or fluid intake


-medications


-pregnancy


-hypothyroidism


-hypoparathyroidism


-diabetes


-hypokalemia


-hypercalcemia


-psychological/neurological disorders


What are common symptoms in the clinical presentation of constipation?

Nausea


Bloating


Cramping


Difficulty passing stool

What should be included in an assessment of constipation?

Diet (24 hr food/fluid)


Exercise


Bowel pattern # of stools per day


When changed occurred


Straining


Sense of incomplete evacuation


Incontinence/ diarrhea


Abdominal pain


Blood in stool


Complete Medication Review


What could be found on a physical exam of a patient with constipation?

-Signs of dehydration


-weight loss


-abdominal scars


-bowels sounds = increased/decreased


-dullness over stool or mass


-rebound

When preforming physical rectal exam in a person with complaints of constipation, what are you looking for?

Sphincter tone


Hemorrhoids


Fissure


Lesion


Impaction

What central nervous system drugs cause constipation?

Antidepressants


Antipsychotics


Anxiolytics


Opiate analgesics

What cardiovascular / musculoskeletal drugs cause constipation?

Antihypertensive


Diuretics


Cardiotonics


Hematologic


Muscle relaxants

What classes of drugs can cause constipation?

Antacids


Anticholinergic


Antibiotics


Antihistamines

What diagnostic blood work can be done for constipation?

CBC, TSH, Chem profile: calcium, potassium, glucose, stool for OB, UA and culture

What are constipation diagnostic tests?

Flat plate & upright of abdomen


CT of abdomen


Barium enema


Colonscopy

What are emergent problems with constipation that would require a referral?

Ileus


Intrabdominal infection


(Appendicitis, diverticulitis)


Toxic mega colon


Obstruction

What is phase 1 of constipation management?

Lifestyle changes


-Exercise regularly


-Develop regular bowel habits


Dietary changes


-increase fiber


-decrease fats (cheese)


-increase fluids 1.5 to 2 liters/day

What is phase 2 of constipation treatment?

Bulk forming laxatives


Metamucil


FiberCon

What is phase 3 of constipation treatment?

Stool stoftners

What is phase 4 of constipation treatment?

Osmotic laxatives:


Lactulose


Miralax


MOM



What is phase 5 of constipation treatment?

Stimulant laxatives:


Ducolax, senokot


What is phase 6 of constipation treatment?

Chloride channel activators:


Lubiprostone (Amitiza)

What is phase 7 of constipation treatment?

Combination oral laxatives


Enema


Suppository

What subcutaneous injections counteracts opioid induced hypomotility?

Methyl naltexone (relistor)

What is diverticular disease?

Diverticulum (single)


Diverticula (pleural)


--saclike protrusion of mucosa through the colon wall


--defects in large colon, especially sigmoid


--incidental finding on colonoscopy, BE or CT

What is diverticulosis?

prescence of numerous non-inflammed diverticula, asymptomatic

What is diverticulitis?

Inflammation of diverticula, may lead to perforation, abscess, fistula, or hemorrhage

What is the physiology behind diverticula formation?

--herniation of muscular layer of colon (increased pressure in areas of relative weakness)


--low fiber diets decrease bulk of stool requiring increased pressure to move fecal matter along


--result of loss of non-absorbable fiber content in diet

What is the presentation of diverticulitis?

--colicky or steady abdominal pain typically in LLQ


--fever, N/V possible


--irregular defecation: constipation/loose stools


PAINLESS lower GI bleeding (brisk rectal bleeding of maroon or bright red blood)


--may feel thickened palpable sigmoid & descending colon

What labwork may be done for diverticulitis diagnostics?

CBC with differential


Leukocytosis - left shift


Anemia


Stool for occult blood


ESR


UA

What radiology may be done for diverticulitis diagnostics?

CT scan of abdomen w. contrast (preferred imaging for acute)


X-ray: flat plate of abdomen to show ileus, free air (perforation)


Ultrasound to show mass or abscess


Procto-sigmoidoscopy to rule out mass


Barium enema (never done for acute, can cause bowel perforation)

What is the conservative management for diverticulitis?

NOT-ACUTE:


clear liquids 2-3 days


abx - treat for 7-14 days


ciprofloxacin 500 bid plus metronidazole 500 tid OR trimethoprim-sulfamethoxazole 160/80 bid w. flagyl OR amoxicillin-clavulanate ER 1000/62.5 mg 2 tab bid


bleeding stops spontaneously


prevention: high fiber diet (no seeds)

What are the complications of diverticulitis?

40-50 yrs


abscess, fistula, obstruction


abscess with rupture & suppurative peritonitis


perforation with fecal peritonitis

What is challeneging about the presentation of diverticulitis in an older adult?

minimal abdominal pain


no fever


abdomen exam with benign findings


--> untreated may lead to sepsis

What characterizes peptic ulcer disease?

ulceration of gastric and duodenal mucosa

What are the risk factors for peptic ulcer disease?

NSAID use


Helicobacter pylori infection


Family history


Smoking, caffeine, alcohol


stress


Cirrhosis


COPD

What is the pathophysiology of a peptic ulcer?

--high concentration of acid & pepsin secreted by parietal cells of stomach to digest food


--GI mucosa secretes alkaline mucus to protect muscosa from self-digestion


--H. pylori acquired by oral-fecal route attaches to gastric mucosa & injures local tissue


(80% w/ duodenal ulcer & 60% w/gastric ulcer)

What is the presentation of a duodenal ulcer?

more common


pain: epigastric, sharp, gnawing, burning, aching


1-3 hours after eating as stomach empties after eating a meal


AWAKENED DURING THE NIGHT


relieved by eating food, antacids, or vomiting


weight gain possible due to frequent meals

What is the presentation of a gastric ulcer?

pain: epigastric, sharp, gnawing, burning, aching


pain becomes worse with eating food because of increase in gastric acid


nausea, vomiting, anorexia, weight loss more common



What diagnostic blood work should be done for a peptic ulcer?

CBC (to check for anemia)


Stool for occult blood


H. pylori serum antibody

How is H. pylori testing done?

Gastric biopsy ***


Urea breath testing (PPIs can give false negative)


Fecal antigen testing


Serum antibody - use breath and fecal first

When do you refer for upper endoscopy for peptic ulcer?

age > 50 yr


alarm symptoms:


weight loss


anemia


GI bleed

What is standard quadruple therapy (7 days) for H. Pylori eradication?

PPI: choose from omeprazole (prilosec), lansoprazole (prevacid), rabeprazole (aciphex), esomeprazole (nexium) BID


& Bismuth subsalicylate (Pepto Bismol) QID


& Metronidazole QID


& Tetracycline QID



What is sequential therapy (10 days) for H. Pylori eradication?

PPI: choose from omeprazole (prilosec), lansoprazole (prevacid), rabeprazole (aciphex), esomeprazole (nexium) BID


& Amoxicillin BID (days 1-5)


& Clarithromycin BID (days 6-10)


& Tinidazole (days 6-10)

What is triple therapy (14 days) for H. Pylori eradication?

PPI: choose from omeprazole (prilosec), lansoprazole (prevacid), rabeprazole (aciphex), esomeprazole (nexium) BID


& Clarithromycin BID


& Amoxicillin BID


OR


Metronidazole BID

What is the pharmacological management of ulcers?

PPI: 1st for 4-8 week


omeprazole (prilosec), lansoprazole (prevacid), rabeprazole (aciphex), esomeprazole (nexium)


H2 receptor antagonists: 2nd


ranitidine (zantac), famotidine (pepcid), nizatidine (axid)

What preventative measures should be taken to stop ulcer formation?

Stop NSAIDs


(alternative COX2 inhibitor / misoprostol [cytotec])


Stop smoking


Restrict alcohol


Dietary modification