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41 Cards in this Set

  • Front
  • Back
Pressure
the force applied or distributed over a surface as force per unit area
Pressure equation
P= F/A
2 Sources of Force
1. force of gravity
2. Energy within atom or molecule (kinetic molecular theory)
Units of force
Newton
N = kg m/s squared
1 mmHg = ? cm water
1mmHg = 1.36 cm water
Absolute pressure
Gauge pressure + Atmospheric pressure
Gauge pressure
what the gauge states
Flow
the quantity of a fluid (gas or liquid) passing a point in unit time
PRESSURE represents what type of energy
Potential or stored energy
FLOW represents what type of energy
Kinetic energy (energy of motion)
Flow equation
F = Q/T
Q = quantity (mass or volume)
T = time
Laminar Flow
- occurs in smooth tubes
- occurs at low flow rates
- Flow is greatest at the center & approaches zero at the walls
- there must be a pressure gradient across the ends of the tube
- linear relationship between Pressure and Flow
- increase polarity increases viscosity
In Laminar Flow there is a linear relationship between:
Linear relationship between Pressure and Flow
In Laminar Flow what is the key factor
Viscosity
Viscosity
- a measure of a liquid's resistance to flow
- the greater the viscosity, the greater the interaction between adjacent fluid layers so there is decreased flow
Poiseuille's Equation relationships
Flow is directly proportional to Pressure

Flow is inversely proportional to Viscosity and Length of tube
According to Poiseuille's Equation if radius doubles what happens to flow?
If radius doubles than Flow Increases by 16 times
- (diameter is radius doubled)
The greatest role in determining the rate of flow thru a vessel
radius or diameter of the blood vessel plays the most important role in determining the rate of flow
2/3 of systemic vascular resistance is due to what?
is due to blood flow in the smallest arterioles ranging diameter from 4-25 micrometers
OHM's Law (Equation)
Q = (P1-P2)/R

R = (P1-P2)/Q
What does OHM's Law allow us to do?
it allows us to calculate SVR and C.O.
- use this law to describe blood flow through a vessel
Turbulent Flow
- molecules travel in nonparallel paths leading to eddy currents
- occurs at points of constriction causing increased fluid velocity
- Non-linear between Flow and Pressure
- Pressure is approximately proportional to the square root of the flow rate
- Occurs with increased or variable Velocity
- Density is the important property
- greater resistance than for laminar flow at the same flow rate
In Turbulent Flow what is the important property
Density is the important property in Turbulent flow
Reynold's Number
Determines if the flow is laminar or turbulent
- relates ratio of density of a gas to its viscosity
Reynold's Number Equation
Re = 2rvd/n
Critical Flow rate
Change from Laminar to Turbulent flow
- depends on velocity of gas which...
- depends on volume flow and diameter of tube
Critical Flow is defined by what?
Defined by the gas and temperature
- with warming of anesthetic gases as they enter the airway, the critical flow rises due to the decreased density from increased temperature
Examples of Laminar Flow
- Quiet breathing
- Blood flow except at bifurcations
Examples of Turbulent Flow
- Coughing, speaking, deep breathing
- Increased secretions
- Carotid stenosis
Heliox
clinical use of density and viscosity to decrease resistance to flow
- used in acute, sever airway obstruction: subglottic edema, foreign bodies, tracheal tumors
- Only Helium has a lower density to viscosity ratio
Bernoulli's Law
when liquids flow through a tube, a pressure is exerted against the sides of the tube. The faster the flow rate, the less side pressure is generated. If the pathway is varried in cross-sectional area, forward velocity is FASTEST and side pressure is LEAST at the point of greatest constriction
- rational behind Venturi's Priniciple
Venturi's Principle
pressure is lowest at area of constriction d/t fast flow in the middle and when there's a pressure decrease than air can be entrained from outside
- how nebs and venturi masks work
Jet Ventilation
used in upper airway lesions in OR.
- inhalation is by pressing toggle and expiration is passive.
- measure ventilation by O2 sat and chest rise
Tension
a tangential force in Newtons/meters acting on a length of the wall.
- caused by the smooth muscle and elastic tissue
- balance between tension and the fluid pressure inside the tube to prevent it from collapsing or distending
Law of Laplace for a tube or cylinder
P = Tension/Radius
Law of Laplace for a sphere
P = 2 Tension/Radius
transmural pressure (hydrostatic pressure)
pressure that distends the tube
Explanation of Law of Laplace
- explains how aorta can sustain high pressures and how capillary with much smaller radius can also sustain pressure of 100mmHg
- Tiny, thin-walled capillaries can withstand surprisingly large pressures because of their tiny radius
- aorta has elastin, collagen, and smooth muscle where as capillaries only have elastin and collagen
What happens to the wall tension required to sustain a developing aortic aneurysm when the radius increases from 2cm to 3cm
Tension Increases with Increased Radius to be able to withstand pressure
Law of Laplace regarding Aneurysms
Wall tension is proportional to vessel radius for cylindrical vessels. Approaching a spherical shape gives less tension than the same radius cylinder, but continued expansion produces wall tension exceeding that of the original cylinder
Law of Laplace regarding blood pressure measurements
- as the distended heart fails the radius increases and the pressure falls unless the muscle contracts proportionally more forcefully
- as distended heart fails the radius increases