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17 Cards in this Set

  • Front
  • Back
drug of choice for anaphylactic shock
epinephrine
differentiate receptor agonism between low and high dose epinephrine
low - B1 > B2 > a1
high - a1 = a2 > B1
therefore at low doses, epinephrine will actually lower SVR due to B2 agonism
1st line agent for LV cardiogenic shock where hypotensive death is eminent
dopamine
1st line agent for septic shock with low CO and slightly low SVR
dopamine
low dose of dopamine
D1 agonist - lower SVR due to dilation of splanchnic and renal arteries
high dose of dopamine
a1 > B1 > B2 - increase HR, contractility, PAWP, SVR
receptor effects of dobutamine
B1 > B2 agonist
1st line agent for LV cardiogenic shock where pulmonary edema death is eminent
dobutamine
inhibits PDE3 therefore increases cAMP and contractility
Milrinone
characteristics of phenylephrine
a1 > a2 agonist - increase SVR with decrease reflex in HR
drug of choice to treat severe systolic dysfunction
Milrinone
2nd line agent in refractory shock following NE or dopamine
phenylephrine
1st line agent for septic shock with markedly low SVR
norepinephrine
a1 = a2 = B1 agonist
norepinephrine
much more relative increase in SVR than HR
norepinephrine
much more relative increase in HR than SVR
high dose dopamine
drug that increases contractility while lowering SVR and PAWP
dobutamine