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17 Cards in this Set
- Front
- Back
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drug of choice for anaphylactic shock
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epinephrine
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differentiate receptor agonism between low and high dose epinephrine
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low - B1 > B2 > a1
high - a1 = a2 > B1 therefore at low doses, epinephrine will actually lower SVR due to B2 agonism |
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1st line agent for LV cardiogenic shock where hypotensive death is eminent
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dopamine
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1st line agent for septic shock with low CO and slightly low SVR
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dopamine
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low dose of dopamine
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D1 agonist - lower SVR due to dilation of splanchnic and renal arteries
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high dose of dopamine
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a1 > B1 > B2 - increase HR, contractility, PAWP, SVR
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receptor effects of dobutamine
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B1 > B2 agonist
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1st line agent for LV cardiogenic shock where pulmonary edema death is eminent
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dobutamine
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inhibits PDE3 therefore increases cAMP and contractility
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Milrinone
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characteristics of phenylephrine
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a1 > a2 agonist - increase SVR with decrease reflex in HR
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drug of choice to treat severe systolic dysfunction
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Milrinone
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2nd line agent in refractory shock following NE or dopamine
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phenylephrine
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1st line agent for septic shock with markedly low SVR
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norepinephrine
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a1 = a2 = B1 agonist
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norepinephrine
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much more relative increase in SVR than HR
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norepinephrine
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much more relative increase in HR than SVR
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high dose dopamine
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drug that increases contractility while lowering SVR and PAWP
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dobutamine
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