Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
10 Cards in this Set
- Front
- Back
|
What aggravates porphyria?
|
Pregnancy
|
|
|
What provokes porphyria?
|
BaKED BuMPS: Barbiturates, Ketamine, Ethanol, Dilantin, Benzos, Meprobamate, Pentazocine, Sepsis (+dehydration and hypoglycemia)
|
|
|
What is a safe anesthetic for known porphyria?
|
Inhalation agents, narcotics, droperidol, chloropromazine, anticholinergics, anticholinesterases, depolarizing/nondepolarizing muscle relaxants.
|
|
|
What causes atypical pseduocholinesterase?
|
inheritated change of gene responsible for liver enzyme production
|
|
|
What is the effect of atypical pseudocholinesterase?
|
Slowed hydrolysis of Sux, miva, ester-type LA
|
|
|
How is atypical pseduocholinesterase dx'd?
|
Abnormal dibucaine/fluride #
|
|
|
What #s are associated w/ a prolonged response to sux?
|
Dibucaine: 50-60 (nml 78-86); Fluride: 25-35 (nml 55-65)
|
|
|
What drugs decrease serum cholinesterase?
|
B-blockers, steroids, P450 induction
|
|
|
What pathological states decrease serum cholinesterase?
|
TaBeL UP MOM: TB, burns, liver dys, malignancy, uremia, organophosphates, malnutrition, pregnancy
|
|
|
What are the four major pathologies to check for in an interview?
|
MH, Adrenal suppression, Porphyria, Atypical pseduocholinesterase
|
