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41 Cards in this Set
- Front
- Back
Antiplatelet Class
a)CI's (plavix/ticlid only) b)Drug interactions (2) c)Pt consultation (2) |
1)active bleed
1)NSAIDs (GI bleed) 2)warfarin or ASA therapy (incr bleed) 1)report unusual bleeds 2)inform MDs/DDS of use |
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Plavix
a)pharmacology b)drug interaxns c)ADR's (3) |
a)irreversible platelet inhibition via ADP
b)phenytoin c)HA, dizzy, arthralgia |
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Ticlid
a)pharmacology b)precautions c)ADR's d)other consultation |
a)irreversible platelet inhibition via ADP
b)blood dyscrasias c)neutropenia, thrombocytopenia d)CBC!!! |
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Persantine
a)indication b)ADR (3) c)mechanism d)generic |
a)adjunct therapy w/ warfarin post valve replacement
b)drowsy, dizzy, hypotension c)Inhibits PDE (hence the ADRs) d)dipyradimole |
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Intermittent claudication drugs
a)class indications b)class pt consultation (2) c)2ex |
a)decr symptoms (which means incr in symptom free walking time)
b1)may take extended time prior to symptom relief b2)tell pt to self monitor how far they can walk c)trental, pletal |
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Pentoxifylline (Trental)
a)pharmacology b)drug interaxns c)ADR (2) d)consultation (2) |
a)makes RBCs more comformable and changes blood viscosity
b)incr theophylline levels (which is used in COPD pts) c)drowsy, GI d1)take w/ food d2)effects can take 4-12wks |
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Pletal
a)generic name b)drug interaxns c)CI d)ADR's e)pt consultation |
a)cilstazol
b)diltiazem, grapefruit (INHIBITORS OF 3A4) c)CHF of any severity b/c pletal is PDE3 inhibitor***** d)HA, dizzy e)effects take 2-12wks |
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Coumadin
a)tablet strengths b)FDA indications (2) c)DRUG INTERACTIONS (4) d)CI (2) |
a)1, 2, 2.5, 3, 4, 5, 6, 7.5, 10
b)VTE, A.fib c)Bactrim, amiodarone, fluconazole, flagyl d)pregnancy, bleeds |
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Coumadin pt consult (4)
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1)take only as directed
2)avoid alcohol and ASA 3)do not start/stop other meds unless indicated 4)inform MD/DDS of use |
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Alpha1 blockers
a)precautions (2) b)drug interactions |
a1)additive hypotension w/ other antihypertensives
a2)risk of syncope w/ 1st dose or noncompliance b1)additive effects w/ other antihypertensives/vasodilators/diuretics |
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Alpha1 blockers
a)class ADRs (4) b)class pt consult (3) c)3ex |
a)dizzy, HA, fatigue, edema
b1)1st dose @ bedtime unless XR b2)orthostatic counseling b3)compliance VERY important c)cardura, hytrin, minipres |
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Hytrin
a)FDA indications (2) |
a)HTN
b)BPH |
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Cardura/XL
a)kinetics b)pt consult (3) |
a)IR has peaks @ 2-3h, XR @ 8-9hrs
b1)IR first dose @ bedtime b2)XL take in morning w/ food b3)orthostatic counseling |
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Minipres
a)generic name b)FDA indications |
a)prazosin
b)HTN |
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Apresoline
a)FDA indication (3) b)precautions c)ADRs (2) d)pt consult (2) e)generic name |
a1)HTN
a2)+/- nitrate in CHF a3)w/ isosorbide as BiDil for blacks w/ CHF b)drug induced SLE w/ long term use c)dizzy, edema d1)take w/ food d2)report fatigue/aches (early signs of SLE) e)HYDRALAZINE |
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Catapres
a)mechanism b)dosage forms c)pt consult (2) |
a)alpha2 agonist= decr SNS
b)tablets, transdermal(TTS) (TTS is 7days worth) c1)do NOT abruptly dc c2)TTS: apply to hairless, healthy skin and rotate site every 7d |
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Catapres big drug interaction
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w/ a BB, if Clonidine dc'd can have incr BP b/c chronic BB use can up regulate beta receptors; dc BB off slowly first then clonidine
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Dihydropyridine CCB class
a)precautions (2) b)class ADR's (3) c)pt consult |
a1)reflex tachycardia due to vasodilation
a2)incr angina b)edema, HA, flushing c)orthostatic counsel |
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Non-dihydropyridine
a)class CI's (3) b)class precautions c)class drug interaxns d)class ADR's (3) e)pt consult |
a1)sick sinus syndrome
a2)2/3rd degree AV block a3)systolic BP less than 90 b1)CHF (due to - inotropic effect) c)tegretol effects enhanced d)edema, HA, BRADYCARDIA e)orthostatic counseling |
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Nifedipine
a)generic name b)dosage forms c)drug interactions (2) d)pt consult (2) |
a)Procardia
b)capsule/XL tablets c)cimetidine/grapefruit d1)take on empty stomach d2)do not crush/cut XL |
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Plendil
a)generic name b)ADR c)pt consult |
a)felodipine
b)rare gingival hyperplasia c)good dental hygiene |
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Norvasc
a)FDA indications (2) |
1)HTN
2)vasospastic/chronic angina |
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Lotrel
a)generic name b)FDA indication |
a)amlodipine & benzapril (Lotensin)
b)HTN |
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Cardizem
a)dosage forms b)FDA indications c)pt consult d)drug interactions (2) |
a)oral and IV
b)regular tabs (angina); CD (HTN) c)take on empty stomach d1)incr serum levels of cyclosporine A d2)cimetidine increases diltiazem levels |
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Dilacor XR
a)generic name b)pt consult c)drug interactions (2) |
a)diltiazem XR
b)take on empty stomach c1)incr serum levels of cyclosporine A c2)cimetidine increases diltiazem serum levels |
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Verapamil
a)dosage forms (2) b)FDA indications (2) c)drug interactions d)CI's e)ADR's f)pt consult (2) |
a)oral and IV
b)angina and HTN c)therapeutic and toxic effects of BB and digoxin enhanced d)SEVERE LVdysfxn e)CONSTIPATION f1)take on empty stomach f2)do not crush SR |
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Nitrates
a)class CI b)class precautions (2) c)class drug interaxns (2) |
a)viagra like drugs
b1)tolerance w/ long term/daily use b2)caution if starting during hypotension or volume depletion c1)alcohol (vasodilation) c2)arterial vasodilatiors (like CCB's) |
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Why no nitrate monotherapy?
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due to tolerance w/ long term/daily use
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Nitrates
a)class ADRs (4) b)class pt consult (3) c)4ex |
a1)HA
a2)dizzy a3)flushing a4)nausea b1)dose w/ a nitrate free interval b2)orthostatic hypotension b3)avoid alcohol c)isosorbide dinitrate/mononitrate, nitrostat, nitrodur |
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Isosorbide Mononitrate
a)pt consult (2) |
a)DO NOT CRUSH
b)can split along SCORES, but then swallow whole |
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Nitrostat
a)dosage forms b)ADR's c)pt consult (5) |
a)SL, IV
b)rapid pulse reflex c1)SIT DOWN b4 take SL dose c2)dissolve under tongue c3)for angina take 3 single tablets 5min apart (if no relief call 911) c4)store in original amber vial c5)HA |
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Nitro-Dur
a)dosage form b)pt consult (3) |
a)transdermal patch
b1)apply patch qAM to chest/back b2)rotate application site daily b3)remove patch after 12h |
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Lanoxin
a)FDA indications (3) |
a)CHF
b)A.fib/flutter c)DOSE ADJUST IN RENAL IMPAIRMENT |
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Lanoxin
a)drug interactions (3) b)ADR's (5) |
a)diuretics (incr digoxin effect due to hypokalemia); amiodarone REDUCES lanoxin CL; erythromycin
b1)anorexia b2)nausea b3)bradycardia b4)blurred vision b5)HA |
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Amiodarone
a)generic name b)FDA indications c)pt consultation (2) d)kinetics |
a)cordarone, pacerone
b)ventricular/supreventricular arrhythmias c1)lab monitoring/surveillance for toxicity VERY IMPORTANT c2)must assure frequent warfarin monitoring will occur d)response may take weeks b/c half life 50d |
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Amiodarone
a)drug interactions (2) b)CI (2) c)ADR's (2) |
a)digoxin, WARFARIN (INCR IN INR)
b1)sinus node dysfxn b2)pulmonary/heptotoxicities (pulmonary can be fatal) c1)thyroid/ocular abnormalities c2)photosensitivity |
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Glyburide can induce...
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hypoglycemia
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Why take coreg w/ food?
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to decr orthostasis
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Cordarone
a)inhibits.... (3) b)Warfarin adjustment w/ this |
1)3A4
2)2C9 3)2D6 1)25-50% decr in dose and titrate to INR goal |
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Avapro (Irbesartan) inhibits...
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2C9
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Quinapril CHF dosing
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start @ 5mg bid; increase to 20-40mg bid eventually
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