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41 Cards in this Set

  • Front
  • Back
Antiplatelet Class
a)CI's (plavix/ticlid only)
b)Drug interactions (2)
c)Pt consultation (2)
1)active bleed

1)NSAIDs (GI bleed)
2)warfarin or ASA therapy (incr bleed)

1)report unusual bleeds
2)inform MDs/DDS of use
Plavix
a)pharmacology
b)drug interaxns
c)ADR's (3)
a)irreversible platelet inhibition via ADP
b)phenytoin
c)HA, dizzy, arthralgia
Ticlid
a)pharmacology
b)precautions
c)ADR's
d)other consultation
a)irreversible platelet inhibition via ADP
b)blood dyscrasias
c)neutropenia, thrombocytopenia
d)CBC!!!
Persantine
a)indication
b)ADR (3)
c)mechanism
d)generic
a)adjunct therapy w/ warfarin post valve replacement
b)drowsy, dizzy, hypotension
c)Inhibits PDE (hence the ADRs)
d)dipyradimole
Intermittent claudication drugs
a)class indications
b)class pt consultation (2)
c)2ex
a)decr symptoms (which means incr in symptom free walking time)
b1)may take extended time prior to symptom relief
b2)tell pt to self monitor how far they can walk
c)trental, pletal
Pentoxifylline (Trental)
a)pharmacology
b)drug interaxns
c)ADR (2)
d)consultation (2)
a)makes RBCs more comformable and changes blood viscosity
b)incr theophylline levels (which is used in COPD pts)
c)drowsy, GI
d1)take w/ food
d2)effects can take 4-12wks
Pletal
a)generic name
b)drug interaxns
c)CI
d)ADR's
e)pt consultation
a)cilstazol
b)diltiazem, grapefruit (INHIBITORS OF 3A4)
c)CHF of any severity b/c pletal is PDE3 inhibitor*****
d)HA, dizzy
e)effects take 2-12wks
Coumadin
a)tablet strengths
b)FDA indications (2)
c)DRUG INTERACTIONS (4)
d)CI (2)
a)1, 2, 2.5, 3, 4, 5, 6, 7.5, 10
b)VTE, A.fib
c)Bactrim, amiodarone, fluconazole, flagyl
d)pregnancy, bleeds
Coumadin pt consult (4)
1)take only as directed
2)avoid alcohol and ASA
3)do not start/stop other meds unless indicated
4)inform MD/DDS of use
Alpha1 blockers
a)precautions (2)
b)drug interactions
a1)additive hypotension w/ other antihypertensives
a2)risk of syncope w/ 1st dose or noncompliance

b1)additive effects w/ other antihypertensives/vasodilators/diuretics
Alpha1 blockers
a)class ADRs (4)
b)class pt consult (3)
c)3ex
a)dizzy, HA, fatigue, edema
b1)1st dose @ bedtime unless XR
b2)orthostatic counseling
b3)compliance VERY important

c)cardura, hytrin, minipres
Hytrin
a)FDA indications (2)
a)HTN
b)BPH
Cardura/XL
a)kinetics
b)pt consult (3)
a)IR has peaks @ 2-3h, XR @ 8-9hrs
b1)IR first dose @ bedtime
b2)XL take in morning w/ food
b3)orthostatic counseling
Minipres
a)generic name
b)FDA indications
a)prazosin
b)HTN
Apresoline
a)FDA indication (3)
b)precautions
c)ADRs (2)
d)pt consult (2)
e)generic name
a1)HTN
a2)+/- nitrate in CHF
a3)w/ isosorbide as BiDil for blacks w/ CHF
b)drug induced SLE w/ long term use
c)dizzy, edema

d1)take w/ food
d2)report fatigue/aches (early signs of SLE)
e)HYDRALAZINE
Catapres
a)mechanism
b)dosage forms
c)pt consult (2)
a)alpha2 agonist= decr SNS
b)tablets, transdermal(TTS) (TTS is 7days worth)
c1)do NOT abruptly dc
c2)TTS: apply to hairless, healthy skin and rotate site every 7d
Catapres big drug interaction
w/ a BB, if Clonidine dc'd can have incr BP b/c chronic BB use can up regulate beta receptors; dc BB off slowly first then clonidine
Dihydropyridine CCB class
a)precautions (2)
b)class ADR's (3)
c)pt consult
a1)reflex tachycardia due to vasodilation
a2)incr angina
b)edema, HA, flushing
c)orthostatic counsel
Non-dihydropyridine
a)class CI's (3)
b)class precautions
c)class drug interaxns
d)class ADR's (3)
e)pt consult
a1)sick sinus syndrome
a2)2/3rd degree AV block
a3)systolic BP less than 90

b1)CHF (due to - inotropic effect)
c)tegretol effects enhanced
d)edema, HA, BRADYCARDIA
e)orthostatic counseling
Nifedipine
a)generic name
b)dosage forms
c)drug interactions (2)
d)pt consult (2)
a)Procardia
b)capsule/XL tablets
c)cimetidine/grapefruit
d1)take on empty stomach
d2)do not crush/cut XL
Plendil
a)generic name
b)ADR
c)pt consult
a)felodipine
b)rare gingival hyperplasia
c)good dental hygiene
Norvasc
a)FDA indications (2)
1)HTN
2)vasospastic/chronic angina
Lotrel
a)generic name
b)FDA indication
a)amlodipine & benzapril (Lotensin)
b)HTN
Cardizem
a)dosage forms
b)FDA indications
c)pt consult
d)drug interactions (2)
a)oral and IV
b)regular tabs (angina); CD (HTN)
c)take on empty stomach
d1)incr serum levels of cyclosporine A
d2)cimetidine increases diltiazem levels
Dilacor XR
a)generic name
b)pt consult
c)drug interactions (2)
a)diltiazem XR
b)take on empty stomach
c1)incr serum levels of cyclosporine A
c2)cimetidine increases diltiazem serum levels
Verapamil
a)dosage forms (2)
b)FDA indications (2)
c)drug interactions
d)CI's
e)ADR's
f)pt consult (2)
a)oral and IV
b)angina and HTN
c)therapeutic and toxic effects of BB and digoxin enhanced
d)SEVERE LVdysfxn
e)CONSTIPATION
f1)take on empty stomach
f2)do not crush SR
Nitrates
a)class CI
b)class precautions (2)
c)class drug interaxns (2)
a)viagra like drugs
b1)tolerance w/ long term/daily use
b2)caution if starting during hypotension or volume depletion

c1)alcohol (vasodilation)
c2)arterial vasodilatiors (like CCB's)
Why no nitrate monotherapy?
due to tolerance w/ long term/daily use
Nitrates
a)class ADRs (4)
b)class pt consult (3)
c)4ex
a1)HA
a2)dizzy
a3)flushing
a4)nausea

b1)dose w/ a nitrate free interval
b2)orthostatic hypotension
b3)avoid alcohol

c)isosorbide dinitrate/mononitrate, nitrostat, nitrodur
Isosorbide Mononitrate
a)pt consult (2)
a)DO NOT CRUSH
b)can split along SCORES, but then swallow whole
Nitrostat
a)dosage forms
b)ADR's
c)pt consult (5)
a)SL, IV
b)rapid pulse reflex

c1)SIT DOWN b4 take SL dose
c2)dissolve under tongue
c3)for angina take 3 single tablets 5min apart (if no relief call 911)
c4)store in original amber vial
c5)HA
Nitro-Dur
a)dosage form
b)pt consult (3)
a)transdermal patch
b1)apply patch qAM to chest/back
b2)rotate application site daily
b3)remove patch after 12h
Lanoxin
a)FDA indications (3)
a)CHF
b)A.fib/flutter
c)DOSE ADJUST IN RENAL IMPAIRMENT
Lanoxin
a)drug interactions (3)
b)ADR's (5)
a)diuretics (incr digoxin effect due to hypokalemia); amiodarone REDUCES lanoxin CL; erythromycin
b1)anorexia
b2)nausea
b3)bradycardia
b4)blurred vision
b5)HA
Amiodarone
a)generic name
b)FDA indications
c)pt consultation (2)
d)kinetics
a)cordarone, pacerone
b)ventricular/supreventricular arrhythmias

c1)lab monitoring/surveillance for toxicity VERY IMPORTANT
c2)must assure frequent warfarin monitoring will occur

d)response may take weeks b/c half life 50d
Amiodarone
a)drug interactions (2)
b)CI (2)
c)ADR's (2)
a)digoxin, WARFARIN (INCR IN INR)

b1)sinus node dysfxn
b2)pulmonary/heptotoxicities (pulmonary can be fatal)

c1)thyroid/ocular abnormalities
c2)photosensitivity
Glyburide can induce...
hypoglycemia
Why take coreg w/ food?
to decr orthostasis
Cordarone
a)inhibits.... (3)
b)Warfarin adjustment w/ this
1)3A4
2)2C9
3)2D6

1)25-50% decr in dose and titrate to INR goal
Avapro (Irbesartan) inhibits...
2C9
Quinapril CHF dosing
start @ 5mg bid; increase to 20-40mg bid eventually