Ppal99 Clues Immunology

Front 1

which cytokine do macrophage stimulate?

Back 1

IL-1

Front 2

which cytokines do T helper cells stimulate?

Back 2

everything other than IL-1

Front 3

what 3 enlarged lymph nodes are most likely malignant?

Back 3

supraclavicular
epitrochlear (above elbow)
inguinal

Front 4

what cells have CD8?
what do these cells respond to?

Back 4

T killer or Tsuppressor cell; responds to MHC-1 (self)

Front 5

which of your cells express MHC-1

Back 5

all except RBC and platelets

Front 6

what cells have CD4?
what do they respond to?

Back 6

T helper cell, responds to MHC-2 (non-self)

Front 7

what type of immunity does TH1 provide?

Back 7

cell-mediated

Front 8

what type of immunity does TH2 provide?

Back 8

humoral

Front 9

what do b cell deficiency patients die of?

Back 9

bacterial infection

Front 10

what is common variable hypogammaglobulinemia?
what would be seen in labs?

Back 10

kids with b cells don't diffentiate in plasma cells ⇒low Ab

Front 11

bruton's agammaglobulinemia
mode of inheritance
labs

Back 11

young adults with defective tyr kinase ⇒ no Ab, X-linked

Front 12

job-buckley syndrome

Back 12

red headed females, stuck in IgE stage

Front 13

multiple myeloma: x-ray, Ig, urine, peripheral smear

Back 13

multiple osteolytic lesions, IgG, mu light chains, rouleaux

Front 14

heavy chain disease

Back 14

IgA and multiple myeloma of GI tract

Front 15

selective IgG2 deficiency pt. get what kind of infections?

Back 15

recurrent encapsulated infections

Front 16

hairy cell leukemia: apprearance, stain

Back 16

fried egg/sunburst appearance, TRAP+

Front 17

ataxia telangiectasia: Ig levels and presentation

Back 17

low IgA, neuro problems

Front 18

hyper IgM syndrome

Back 18

high IgM, low all other Ab

Front 19

what do T cell deficiency paitients die of?

Back 19

viral infection

Front 20

what is selective IgA deficiency? and what infections do they get?

Back 20

transfusion anaphylaxis, mucous membrane infection

Front 21

diGeorge syndrome: what is missing anatomically? and labs

Back 21

no thymus/ inferior parathyroids, low Ca2+

Front 22

chronic mucocutaneous candidiasis and patient presentation

Back 22

T cell defect against candida albicans, chronic fatigue

Front 23

SCID: what is missing anatomically, presentation, life expectancy

Back 23

no thymus, frayed long bones, baby dies by 18 months

Front 24

wiscott-aldrich: labs (3), presentation (2)

Back 24

low IgM, low platelets, high IgA, eczema, petechiae

Front 25

what does CD4 count tell you? what is normal levels?

Back 25

status of HIV (normal = 1,000)

Front 26

what does the viral load tell you?

Back 26

progression of HIV

Front 27

what 5 organs have the most CD4 receptors?

Back 27

blood vessels, brain, testicles, cervix, rectum

Front 28

what are the 3 tests used to screen for HIV?

Back 28

ELIZA
western blot
PCR

Front 29

ELIZA

Back 29

detects IgG Ab to p24 Ag

Front 30

western blot

Back 30

see >2 proteins

Front 31

PCR

Back 31

detects virus (used in babies)

Front 32

what are the live vaccines?

Back 32

"ROBY'S Live Vaccine was an MMR"
Rota virus, Oral polio, BCG, Yellow fever, Small pox, Varicella, MMR

Front 33

what is the definition of AIDS?

Back 33

CD <200 μL or clinical symptoms

Front 34

what is primary biliary cirrhosis? antibody, sex and presentation

Back 34

anti-mitochondrial Ab, puritus, females

Front 35

primary sclerosing cholangitis? antibody, biopsy and associated syndrome

Back 35

p-ANCA Ab, bile duct inflammation, onion skinning, IBD

Front 36

type I autoimmune hepatitis antibody and more common in what sex?

Back 36

anti-SM Ab, young women

Front 37

type II autoimmune hepatitis antibody and more common in what patient

Back 37

anti-LKM Ab, kids

Front 38

bullous pemphigoid antibody and how does it present on the skin?

Back 38

anti-hemidesmosome Ab, skin bulle

Front 39

celiac sprue antibody and presentation

Back 39

anti-gliaden Ab, eating wheat which leads to steatorrhea

Front 40

celiac sprue

Back 40

anti-gliaden Ab, eating wheat⇒ steatorrhea

Front 41

CREST syndrome antibody

Back 41

anti-centromere Ab

Front 42

dermatitis herpetiformis antibodie(s), presentation

Back 42

anti-BMZ Ab, anti-endomysial Ab, vesicles on anterior thigh

Front 43

dermatomyositis antibody, presentation

Back 43

anti-jo1 Ab, myositis + rash

Front 44

DM type I antibody(s) and presentation (3)

Back 44

anti-islet cell, anti-GAD Ab, polyuria, polydipsia, weight loss

Front 45

drug induced lupus antibody and what are the drugs that causes it?

Back 45

anti-histone Ab, "HIPPPE" causes it

Front 46

gastritis type A antibody, another name for this disease and increase risk of what cancer?

Back 46

anti-parietal cell Ab, atrophic gastritis, adenocarcinoma

Front 47

goodpasture's antibody and what organs are attacked?

Back 47

anti-GBM Ab, attacks lung and kidney

Front 48

grave's disease antibody, presentation (2)

Back 48

anti-TSHr Ab, hyperthyroid, bug eyes, pretibial myxedema

Front 49

guillain-barre antibody, presentation and onset

Back 49

anti-ganglioside Ab,ascending paralysis, 2 weeks after URI

Front 50

hashimoto's antibody (2), presentation

Back 50

anti-microsomal Ab =TPO, hypothyroid

Front 51

ITP antibodie(s) and presentation

Back 51

anti-platelet AB, anti-GP2b3a Ab, thrombocytopenia

Front 52

mixed connective tissue disease

Back 52

anti-RNP Ab

Front 53

mononucleosis antibody and presentation

Back 53

heterophile Ab, teenager with sore throat

Front 54

MPGN type II antibodie(s)

Back 54

anti-C3 convertase Ab = C3 nephritic factor

Front 55

multiple sclerosis antibody and presentation

Back 55

anti-myelin Ab,middle age female with vision problems

Front 56

myasthenia gravis antibody and presentations (2)

Back 56

anti-Ach Ab, female with ptosis, weaker as day goes by

Front 57

paroxysmal hemolysis antibody and presentation

Back 57

donath landsteiner Ab, bleeds when cold

Front 58

pemphigus vulgaris antibody and presentation

Back 58

anti-desmosomes Ab, skin sloughs off when touched

Front 59

pernicious anemia antibody and presentation and peripheral smear

Back 59

anti-IFAb, vitamin B12 deficiency => megaloblastic anemia

Front 60

polyarteritis nodosa antibody, presentation and associated disease

Back 60

p-ANCA Ab, attacks gut and kidney, Hep B

Front 61

post-strep GN antibody and presentation

Back 61

ASO Ab, nephritic with complement deposition

Front 62

rheumatoid arthritis antibody and presentation

Back 62

rheumatoid factor, pain worse in the morning

Front 63

scleroderma antibody and presentation

Back 63

anti-scl70 Ab, = anti-Topo I Ab, fibrosis tight skin

Front 64

sjogrens antibody and presentation (3)

Back 64

anti-SSA Ab, dry "sand in eyes" dry mouth, arthritis

Front 65

SLE antibodies (4) and presentation (4)

Back 65

anti-ds Ab/Sm/cardiolipin, rash, photosensitivity, oral ulcers, RF

Front 66

SLE cerebritis antibodie(s)

Back 66

anti-neuronal Ab, anti-ribosomal Ab

Front 67

vitiligo antibody and presentation

Back 67

anti-melanocyte Ab, white patches

Front 68

warm hemolysis antibody and presentation

Back 68

anti-Rh Ab, bleeds at body temp

Front 69

wegener's antibody and presentation

Back 69

c-ANCA Ab, attacks ENT, lungs, kidney

Front 70

HSP: describe and what does it lead to?

Back 70

IgA disease 2 weeks after a common cold => berger's

Front 71

berger's: describe and what does it lead to?

Back 71

IgA disease 2 weeks after a vaccination=> serum sickness

Front 72

alport's: describe and what does this lead to?

Back 72

IgA disease 2 weeks after a diarrhea => HSP, polio