P&p Fall 2014, Exam 2

Front 1

Hypothesis that states that the cranial compartment is incompressible, and volume inside is fixed

Back 1

Monro-Kelly

Front 2

Constituents of cranium

Back 2

Blood, CSF, tissue

Front 3

Volume of CSF in cranium

Back 3

8%

Front 4

Volume of blood in cranium

Back 4

12%

Front 5

Volume of brain in cranium

Back 5

80%

Front 6

ICP is _____ CSF pressure

Back 6

Supratentorial

Front 7

ICP is measured in the _______ or over the ____

Back 7

Lateral ventricles; cerebral cortex

Front 8

Small increases in volume in one component of cranium are initially well

Back 8

Compensated

Front 9

Infants: cranial decompression may occur via expansion of the

Back 9

Skull

Front 10

Posterior fontanelle closes by

Back 10

2 months

Front 11

Anterior fontanelle remains open until

Back 11

1-2 y/o

Front 12

Cranial sutures fuse as late as

Back 12

10 y/o

Front 13

Junction between vascular endothelial cells that are nearly fused

Back 13

BBB

Front 14

BBB is a ____ barries

Back 14

Lipid

Front 15

Can pass freely through BBB

Back 15

CO2

Front 16

Can pass freely through BBB

Back 16

O2

Front 17

Can pass freely through BBB

Back 17

Lipid soluble molecules

Front 18

Poor penetration through BBB

Back 18

Ions

Front 19

Poor penetration through BBB

Back 19

Proteins

Front 20

Poor penetration through BBB

Back 20

Large molecules such as mannitol

Front 21

BBB can be disrupted by

Back 21

Severe HTN

Front 22

BBB can be disrupted by

Back 22

Tumors

Front 23

BBB can be disrupted by

Back 23

Trauma

Front 24

BBB can be disrupted by

Back 24

CVA

Front 25

BBB can be disrupted by

Back 25

Infection

Front 26

BBB can be disrupted by

Back 26

Marked hypercapnia

Front 27

BBB can be disrupted by

Back 27

Hypoxia

Front 28

BBB can be disrupted by

Back 28

Sustained seizure activity

Front 29

Protects the CNS from trauma

Back 29

CSF

Front 30

Adults produce ____ CSF

Back 30

21 mL/hr, 500 mL/day, 150 mL circulating