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14 Cards in this Set
- Front
- Back
Describe where isovolumetic relaxation occurs on the LV pressure-volume loop.
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closure of the aortic valve to opening of the mitral valve
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Describe where isovolumetic contraction occurs on the LV pressure-volume loop.
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closure of the mitral valve to opening of the aortic valve.
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Which is the more potent vasoconstr, angII or ADH?
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ADH (vasopressin)
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Describe the effect of hypercapnia on the cerebral vasculature and on the systemic vasculature.
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Dilation in both cerebral and systemic vessels.
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What Swan-Ganz catheter data suggest LV failure?
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decreased CO and increased preload
PCWP>18mmHg CI<2 |
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What PCWP is indicative of heart failure?
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greater than 18mmHg
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List 5 compensatory responses in the pt with cardiac failure
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1- increased LV preload
2- increased symp tone 3- activation of the renin-angiotensin-aldo system 4- release of AVP 5- ventricular hypertrophy |
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What monitoring is indicated for managing the pt with a history of CHF secondary to diastolic dysfxn?
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CVP or PAC
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Describe the MOA of Milrinone?
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PDE inhibitor--> increased cAMP
In the heart--> increased cAMP increases inotropy In the vessels--> decreaes SVR |
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What potential side effect occurs with inamrinone, but not with Milrinone?
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Thrombocytopenia
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Nitroprusside contains 5 cyanide ions (CN-) and may cause cyanide toxicity. What three rxns may cyanide ions undergo?
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1- binding to MetHb to form cyanometbHb
2- rxn with thiosulfate--> thiocyanates 3- binding to tissue cytochrome oxidase, which interferes with tissue utilization of O2 |
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How do cyanide ions interfere with oxygen utilization at tissue cytochrome oxidase?
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prevents formation of ATP
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List 4 signs and symptoms of cyanide toxicity.
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1- metabolic acidosis
2- cardiac arrhythmias 3- increased venous O2 due to tissue not utilizing O2 4- tachyphylaxis |
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What is your concern giving Phenytoin to the hyperglycemic pt?
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Partially inhibits release of insulin
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