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52 Cards in this Set
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Name 2 CLASS 1 STEROIDS |
HERES 4>>
TEMOVATE DPROLENE ULTRAVATE PSORCON |
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What is the generic name for temovate?
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Clobetasol Dipropionate
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What is the generic name for Diprolene?
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Betamethasone Dipropionate
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What is the generic name for Ultravate?
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Halbetasol Propionate
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What is the generic name for Psorcon?
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Diflorasone diacetate
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Raynaud's phenomenon is also known as constriction of small digital arteries., and is typically associated w/ connective tissue disorders. Persistent blue discoloration seen in those w/ Raynauds is known as ______________
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Acryocyanosis.
Affects the entire hand/foot The cause is unknown! |
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Raynaud's disease occurs in the absence of connective tiisue disorders. What are some of the tx for this?
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Exposure to cold avoided
Vasodilators (nifedipine) Topicals (nitroglycerin) |
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Erythromelalgia is rare It is associated with what condition?
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Thrombocytopenia
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In erythromelalgia the feet begin to burn, and the pt experiences local pain and redness. The pt has defective conduction C fibers.
What works to decrease the hotness? |
Give aspirin daily!
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Livedo reticularis has what kind of appearance?
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Mottled-like net-like appearance.
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Leukocyctoclastic, Henoch-Schonlein purpura, Erythema Nodosum, Wegener's Granulomatosis----- are indicative of _______ vessel vasculitis.
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Small Vessel Vasculitis.
SMV=SMALL VESSEL VASCULITIS |
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Cutaneous Leukocytoclastic angiitis aka allergic vasculitis has necrosis in vessel walls. Below the knees, numerous lesions are present--- it may progress to ___________.
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Hemorrhagic vessicles/bullae.
SMV |
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What is the tx for leukocytoclastic tx?
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NSAIDS/ ORAL STEROIDS
SMV |
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This condition occurs in children after Strep pharyngitis.
HINT>> H-appens to K -ids after S-trep |
Henoch Schonlien Purpura
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What is the tx for Henoch Schonlien Purpura?
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IV/ORAL steroids
NSAIDs for joint pain |
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Erythema nodusum tx involved?
Occurs most commonly? |
NSAIDS
Children & young adults They experience an inflammatory process of fat (panniculitis) |
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Erythema Nodosum causes include ______________________
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Strep infection, drugs, sarcoidosis, TB, inflamm BOWEL disease
Will resolve in a few days, but 77% infection related resolve in 7 weeks, 30% idiopathic |
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Erythema nodosum's diff dx should include _____________?
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Bed BUG BITES MO FO!
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Perniosis/Pernio (Chilblains) includes localized erythema and swelling. May progress to blisters in fingers and toes.
Happens to horse riders. (lateral aspects of thigs/ cold chapping) What is the tx? |
WEAR WARM CLOTHES.
thumbs up! |
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Wegner's granulomatosis is a rare disease. It is R-O-U-G-H on the body.
what do these letters indicate in wegners? |
R-O-U-G-H
R- radiograph the chest O- oral ulcers U- urinary sediment G- granulomas H- hemoptysis |
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What is the circulating antibody we look for in dx wegners?
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C-ANCA
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What is the tx for wegners?
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Systemic steroids/or Cyclophosphamide
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How do you treat Wegner's pydoderma gangrenosum like lesion?
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Oral Tacrolimus
SYSTEMIC STEROIDS! |
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Nodular vasculitis occurs in middle ages women---
they experience inflammatory nodules produced by a granulomatous vasculitis in deep dermis on posterior lower legs. It may be idiopathic or TB related. What is the tx? |
TX underlying TB, bed rest, bandages, no smoking!!
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Polyartertis nodosa & kawasaki disease are both examples of what kind of vessel disease?
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Medium sized vessel disease
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Polyarteritis nodosa (PAN) is a rare, necrotizing vasculitis affecting small and medium sized arteries. It is painful.
It occurs more commonly in_____, ______, and ______. |
PAN occurs more commonly in men.
4:1 ratio M/F. It is a multi-system dx, involving the kidneys, heart, liver, and GI, but not the LUNGS! Occurs more commonly in: IV DRUG USERS, LUPUS PTS, HEP B & C PTS |
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TXing PAN consists of?
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Systemic steroids
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Kawasaki disease aka Mucocutaneous lymph node syndrome occurs in medium sized vessels. Most commonly seen in __________
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Irritable, febrile infant or children under 5
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Stomatitis or strawberry tongue is seen in Kawasaki Disease. What other disease is it seen in?
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Wegners granulomatosis
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The hallmark lesion of kawasaki disease is __________________
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Erythematous desquamating perianal eruptions
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Giant cell (Temporal) arteritis occurs in __________ vessels.
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Large vessels.
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Giant cell arteritis commonly affects which arteries?
If left untreated, it can lead to__________ |
The carotids
Blindness. Giant cell can lead to BLINDNESS! |
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Takayasu's arteritis is a progresive granulomatous inflammation of aorta and its major branches.
What is the tx? |
Tx of takaysu's is: PREDNISONE
Occurs in pts <50yrs who are women. Known as pulseless disease! |
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Schamberg's disease's presents how on the skin?
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chronic pigmented purpura!!!
CAYENNE PEPPER SPOTS! |
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Buerger's disease aka thromboangitis obliterans occurs in the upper and lower extremities. commonly occurs in men 20-40.
What is the hallmark indication an individual has buergers? |
PAIN PAIN PAIN & claudication
in the medial arch! |
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What is the tx for buergers?
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Stop smoking!
continue to smoke, lose a limb |
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Lupus erythematous has 4 subtypes.
ACLE (acute cutaneous LE) hallmark lesion is? |
the butterfly rash on the face.
99% will be positive for ANA. ACLE lasts hours/weeks! |
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What is the tx for ACLE?
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Steroids, oral steroids
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Subacute cutaneous LE is more persistent than ACLE ---- last weeks or months.
It presents as scaly superficial inflammatory macules on the chest, arms, and neck. What drugs do you want avoid b/c of their possible links to SCLE? |
LAMISIL
NAPROXEN GRISEOFULVIN |
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BONUS QUESTION:
What is griseofulvin and how does it work? |
Anti-fungal.
The drug binds to tubulin, interfering with microtubule function, thus inhibiting mitosis. |
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Discoid LE is a common chronic form of cutaneous LE.
It involves fixed, indurated erythematous papules and plaques on head and neck. W/O tx, it may persist for years and cause extensive scarring. What is the tx? WHAT FAMOUS SINGER HAS THIS? |
Sunscreen, topical steroids, anti malarials, systemic steroids
seal- as in "kiss from a rose" |
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Schleroderma is a chronic disease that involves micro vasculature and connective tissues.
The cutaneous type is called____________ |
Localized morphea (can be seen on legs)
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Systemic schleroderma is called ______________.
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Progressive systemic sclerosis.
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CREST is seen scleroderma pts.
CREST stands for ____________________ |
C- calcinosis cutis
R- raynauds phenomenon E- esophageal dysfunction S- sclerodactyly T- teleangiectasias |
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Early symptoms of progressive systemic sclerosis.
Early symptoms include _______________. |
Swelling of feet/hands
Develop raynauds telangiectasias May develop ulcerations on fingers & toes |
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Dermatomyositis is a disease of unknown etiology.
What is the hallmark sign you look for on the face? |
Heliotrope eyes
*Looks as if you have purple eyeliner |
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How do you tx dermatomyositis?
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Prednisone
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Gottron's sign is ______________ AND is indicative of dermatomyositis.
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Gottrons sign: pink to purple atrophic scaling lesions
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Futcher's lines aka voight's lines are___________________
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pigmentary lines of demarcation. symmetrical and bilateral.
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Post inflammatory hyperpigmentation is darkening of the skin that results from injury.
(basal layer is interuppted, melanin escapes!) How do you treat this? |
Hydroquinone
Never use higher than 4% |
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What is the tx for vitilago?
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It is by no means definite,
but UVB, light therapy. Also, dermablend make up. |
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Subungual melanomas clues---- include........
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solitary lesions
width>3cm variable pigment rapid increase in size hutchinson's sign yes it can happen to anyone. thumb most comon! DANGEROUS DX: more advanced by the time you diagnose, poorer survival 49% survival in 5 years |
