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13 Cards in this Set
- Front
- Back
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Normal function of Alpha1 receptors
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vasoconstriction
ejaculation contraction of bladder neck and prostate |
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Normal function of Beta 1 receptors
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Heart (increases rate, force of contraction, velocity of conduction in AV node)
Kidney (renin release) |
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Normal function of Beta 2 receptors
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Bronchial dilation
Relaxation of uterine muscle Vasodilation Glycogenolysis |
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Normal function of Dopamine Receptors
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Dilates renal blood vessels
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What is the MOA of Epinephrine
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Activates Alpha 1&2 and Beta 1&2 (lots of therapeutic and adverse effects
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What is the therapeutic uses of Epinephrine
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-EpiPen
-Elevates blood pressure -AV block reverse -Dilation of bronchioles in asthma |
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What are the adverse effects of Epinephrine and Norepinephrine
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Angina pectoris
Hypertensive crisis Necrosis following extravasation Dysrhythmias |
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What is the MOA of Norepinephrine
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Activates Alpha 1&2 and Beta 1
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What is Norepinephrine used for
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hypotensive state
cardiac arrest |
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What adverse effect does Epinephrine have that norepinephrine doesn't
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Hyperglycemia (because E works on B2 and NE doesn't)
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What is Dopamine's receptor specificity
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LOW DOSE : dopamine receptors
MODERATE DOSE: dopamine and beta 1 receptors VERY HIGH DOSE: Alpha1, Beta 1 and dopamine receptors |
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What is the MOA of Metoprolol
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individual beta receptor blocker on both beta 1 and beta 2
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What are the adverse effects of beta-adrenergic antagonists II (ie beta blocker)
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-bradycardia
-AV heart block -Heart failure -rebound cardiac excitation -Inhibition of glycogenolysis -bronchoconstriction |
