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14 Cards in this Set

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Ovary

Mucinous cystadenocarcinoma of ovary, grade 1


Retroperitoneum in 79 year old with metastatic colon cancer

Sclerosing extra medullary hematopoiesis

Bladder


Urothelial ca micro papillary pattern

MPUC highly invasive


Bad prognosis


On histology: finger-like tumor processes clusters in superficial tissue and more cohesive in deep tissue with polarization of the nuclei to the peripheral aspect of the papillae


Prominent retraction artifact


Multiple tumor cells present in the same lacunae is the most useful feature



Inguinal LN


Ck20+


Psa-


Ttf1-

Merkel


Also positive for cd99, pax5

MCV virus polyoma virus linked to the pathology

Colon


Pseudomembranous colitis!


Note lamina propria is not expanded and no hyalinazation unlike ischemic colitis

Due to c diff toxin and antibiotic therapy clinda, cyclo and ampicillin


polyp


Peutz-jeghers polyp

AD


Muccucutanous pig


Polyps mainly jujenum


Sex cord stromal tumor with anular tubules. Ovary.


Large cell calcifying Sertoli cell tumor ( testes)

Mesentery


SFT


Positive: cd99, bcl2, cd34

What tumors have staghorn vessels?

Synovial sarcoma


SFT


Mesenchymal condrosarcoma

Ovary


Immature teratoma

How to grade it?


Number of 4x field with immature component.


Grade 1 less than 1 with that component


Grade 2: 1-3 fields with immature


Grade 3: more than 3 fields contain immature


Vulva


What stains?


Extra mammary paget!!


Ck7+


Ema+


Cam5.2+


Er-


Pr-


S100-


Hmb45-

Thigh mass in 33 year old


LGFMS


Fus/cerb t(7,16)


Remember spindle cell tumor with giant rosette is a subtype of LGFMS

Kidney mass in a 3 year old kid


Congenital mesoblastic nephroma interlacing fascicles of fiber elastic appearing cells with thin tapered bland appearing nuclei. Low mitotic count and abundant stromal collagen


Stains : actin+


Vimentin+


Bcl2-


Cd34-


Ck-


Kidney adult


ADPKD

Kidney tumor?


What stains?


What type? (1 or 2)


Papillary RCC


Type 1- line by single layer of cells with no pleomorphism and absent nucleoli


Stains: vimentin+, cd10+, amacr+, ck7+ tfe3-



Note type 2 is opposite to the description of type 1