Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/12

Click to flip

12 Cards in this Set

  • Front
  • Back
What is autoregulation?
Mechanism by which blood flow is altered to meet the demands of the tissue.
Which organs exhibit autoregulation?
Brain, heart and kidney
What is active hyperemia?
Blood flow to the organ is proportional to the metabolic activity of the organ.
What is reactive hyperemia?
Transient increase in blood flow to an organ after it has undergone a brief period of arterial occlusion.
What mechanisms have been proposed to explain the local control of blood flow?
Myogenic hypothesis; based on vascular smooth muscle contracting when stretched and explains autoregulation, but not active or reactive hyperemia.
metabolic hypothesis; based on tissue supply of O2 matching the tissue's demand and the production of vasodilator metabolites(CO2, H+, K+, lactate and adenosine.
What effects does Histamine and bradykinin have on vasculature?
Arteriolar dilation and venous constriction.
5-hydroxytryptomine and serotonin cause arteriolar constriction. TRUE/FALSE
`TRUE
Prostacyclin and E series prostaglandins(PGE1, E2) cause vasodilation. TRUE/FALSE
TRUE
F series prostaglandins and thromboxane A cause vasoconstriction. TRUE/FALSE
TRUE.
What factors determine autoregulation in the brain?
Local metabolic factors: PCO2)
What factors determine autoregulation in the heart and kidney?
In the heart, local metabolic factors: hypoxia, adenosine and NO.
In the kidney: myogenic and tubuloglomerular feedback.
What factors determine autoregulation in skeletal muscle at rest and with exercise?
At, sympathetic innervation.
With exercise, local metabolic factors, lactate, adenosine and K+.