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12 Cards in this Set

  • Front
  • Back
What relationship is described by a Starling curve?
Change in SV and cardiac output(CO) that occurs due to changes in venous return or end diastolic volume.
What is the expresion for SV?
What is the length tension relationship in the ventricles?
Relates the length of the ventricular muscle cell to th.e force of contraction it generates
What factors govern the Starling/length-tension relationships?
1. Preload
2. Afterload
3. Sarcomere length
4. Velocity of contraction at a fixed muscle length.
What is preload equivalent to?
Ventricular EDV.
What effect do venodilators have on preload?
Decrease it.
What are some things that can cause an increase in preload?
1. Increased blood volume
2. Sympathetic stimulation
3. Exercise(slight increase)
What is afterload equivalent to?
Diastolic arterial pressure
What is afterload proportional to?
Peripheral resistance.
What effect do vasodilators have on afterload?
Decrease it.
What can increase the contractility of the myocardium?
Sympathetic stimulation
Circulating catecholamines(epi)
Abrupt increase in afterload(Anrep effect)
Increased HR(Bowditch effect)
What can decrease the contractility of the myocardium?
Pharmacologic depressants
Parasympathetic stimulation
Loss of myocardium
Congestive heart failure