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6 Cards in this Set

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What is the intracellular/extracellular concentration of common body ions?
IC EC
Na+ 14 140
K 140 4
Ca2+ 10^-7 2.5
Cl- 10 110
HCO3- 10 20
glucose 100 10
what four factors dtermine the amount of uncharged solute the can diffuse across a cell membrane?
1. concentration gradient of the solute
2. solute's diffusion coeff
3. membrane area
4. membrane thickness
what are the properties of simple diffusion?
1. down EC gradient
2. not rate-limiting, represents linear function
3. not saturable
4. no energy required
What are the properties of facilitated diffusion?
1. down EC gradient
2. binds to transport protein that changes conformation to move the ion down the gradient
3. IS rate limiting and saturable b/c depends on number of transport channels
4. No energy required
how does insulin influence the diffusion of glucose?
insulin increases the rate of facilitated diffusion into muscle cells. insulin binds to receptors and speeds the translocation of glucose transprot proteins. the increase in density of glucose transprt proteins permits greater glucose entry into the cell.
characteristics of active transport?
1. against EC gradient
2. requiresa transport protein
3. rate-limiting and saturable
4. requires ATP