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21 Cards in this Set
- Front
- Back
3 different types of respiration |
1. External - gas exchanged into circulation (pulmonary ventilation and pulmonary gas exchange) 2. Transportation of gases by blood 3. Internal - between blood and cells
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What 2 pressure gradients must the pulmonary ventilation mechanism establish? |
1. Pressure in alveoli is lower than atmp to produce inspiration
2. Pressure in alveoli is higher to produce Expiration
Air moves from areas of high to low pressure |
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Boyle's law |
Volume of gas varies inversely With pressure As vol decreases, pressure increases As vol increases, pressure decreases |
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How can alveolar pressure be decreased? |
Increase lung vol |
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What is atmospheric pressure? |
760 mmhg |
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What is pA? |
Alveolar pressure PIP always stays Lower than pA |
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Parietal plura |
Stuck to chest wall |
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Visceral plura |
Stuck to lung wall |
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Compliance |
Ability of pulmonary tissues to stretch making inspiration possible
Aided by surfactant produced by type 2 alveolar cells Most people have high compliance Premies do not make enough surfactant - put on ventilator |
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Elastic recoil |
The tendency of pulmonary tissues to return to a smaller size after being stretched. Occurs passively during expiration |
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What are intercostal muscles used for? |
To push chest out in forced breathing |
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Is diaphragm relaxed during expiration? |
Yes. The diaphragm is also less curved when expiring. |
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Dalton's law |
Partial pressure of gas in a mixture of gases is directly related to the concentration of that gas in the mixture. |
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Pulmonary gas exchange 1 |
Gas exchange from the lungs into the blood. Factors that determine the amount of oxygen that diffuses in the lungs: 1. Oxygen pressure gradient 2. Respiratory minute volume - amt of air that enters lungs in a minute 3. Surface area of Respiratory membrane |
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Factors that facilitate pulmonary gas exchange 1 |
1. Walls of capillaries and alveoli very thin for gas to pass through 2. Alveolar and capillary surfaces are large 3. Blood in a thin layer in capillaries so that each RBC comes close to alveolar air |
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Are pulmonary arteries blue? |
Yes! Pulmonary venules are red |
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Alveolar ventilation |
Airflow to alveoli |
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Alveolar perfusion |
Blood flow to the alveoli Coordinated regulation of perfusion and ventilation increase efficiency of gas exchange |
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Oxygen unloading |
Oxygen unloading from hemoglobin more easily when exercising this is because of increased CO2 levels. (the Bohr effect) |
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Bohr effect |
Increased Pco2 decreases the affinity between O2 and Hb. When exercising oxygen unloading becomes easier |
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Haldane effect |
Increased CO2 loading caused by a decrease in Po2 |