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21 Cards in this Set

  • Front
  • Back

3 different types of respiration

1. External - gas exchanged into circulation (pulmonary ventilation and pulmonary gas exchange)


2. Transportation of gases by blood


3. Internal - between blood and cells


What 2 pressure gradients must the pulmonary ventilation mechanism establish?

1. Pressure in alveoli is lower than atmp to produce inspiration



2. Pressure in alveoli is higher to produce Expiration



Air moves from areas of high to low pressure

Boyle's law

Volume of gas varies inversely With pressure



As vol decreases, pressure increases


As vol increases, pressure decreases

How can alveolar pressure be decreased?

Increase lung vol

What is atmospheric pressure?

760 mmhg

What is pA?

Alveolar pressure


PIP always stays Lower than pA

Parietal plura

Stuck to chest wall

Visceral plura

Stuck to lung wall

Compliance

Ability of pulmonary tissues to stretch making inspiration possible



Aided by surfactant produced by type 2 alveolar cells



Most people have high compliance



Premies do not make enough surfactant - put on ventilator

Elastic recoil

The tendency of pulmonary tissues to return to a smaller size after being stretched. Occurs passively during expiration

What are intercostal muscles used for?

To push chest out in forced breathing

Is diaphragm relaxed during expiration?

Yes. The diaphragm is also less curved when expiring.


Dalton's law

Partial pressure of gas in a mixture of gases is directly related to the concentration of that gas in the mixture.

Pulmonary gas exchange 1

Gas exchange from the lungs into the blood.


Factors that determine the amount of oxygen that diffuses in the lungs:



1. Oxygen pressure gradient


2. Respiratory minute volume - amt of air that enters lungs in a minute


3. Surface area of Respiratory membrane

Factors that facilitate pulmonary gas exchange 1

1. Walls of capillaries and alveoli very thin for gas to pass through


2. Alveolar and capillary surfaces are large


3. Blood in a thin layer in capillaries so that each RBC comes close to alveolar air

Are pulmonary arteries blue?

Yes!


Pulmonary venules are red

Alveolar ventilation

Airflow to alveoli


Alveolar perfusion

Blood flow to the alveoli



Coordinated regulation of perfusion and ventilation increase efficiency of gas exchange

Oxygen unloading

Oxygen unloading from hemoglobin more easily when exercising this is because of increased CO2 levels. (the Bohr effect)

Bohr effect

Increased Pco2 decreases the affinity between O2 and Hb.


When exercising oxygen unloading becomes easier

Haldane effect

Increased CO2 loading caused by a decrease in Po2