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43 Cards in this Set
- Front
- Back
how does the brain make sense of touch?
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transduces so neuron can understand it (ISPS or ESPS). The transduction sends an intercelluar signal to the CNS
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define stimulus
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physical energy that activates the receptor.
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how does transduction occur
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ransduces to intercellular signal via opening ion channels, switching on second messenger systems sends signal to CNS so we know our arm has been touched.
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what are the 4 sensory receptors?
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chemoreceptor
mechanoreceptor photoreceptor thermoreceptor |
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Define adequate stimuli
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any of the 4 sensory receptors that the stimuli is most responsive to
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define transduction
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converting physical signals into intercellular signals that the CNS can understand
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define threshold
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minimum amount of stimuli needed to activate EPSP or IPSP
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define graded potential
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change in the membrane potential in response to the stimulus
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define ESPS
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depolarization, bring M.P. closer to threshold for A.P.
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define ISPS
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inhibitory, increasing M.P. further from threshold from A.P.
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define receptor potential
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produced when receptor is activated by its adequate stimulus and above threshold. Changes in M.P. in response to the stimulus.
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What are the steps in the pathway to the cortex?
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Primary S.N. has sensory receptors in it, transduce stimulus
send signal to second S.N. send signal to thalamus send signal to the cortexx |
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where does fine touch decussate?
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in the medulla
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where does pain/temp decussate?
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in the spinal cord
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who am I?
Mechanical stimuli- vibration deep in dermis large receptive field rapidly adapting |
Pacinian corpuscles
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who am I?
mechanical stimli-stretching deep in dermis lg. receptive field slowly adapting? |
Ruffini
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who am I?
mechanical-flutter/ stroke located in the fingertips small receptive fields slowly adapting |
Meissners
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Who am I?
mechanical- steady pressure and texture superficial layers of the skin small receptive field slowly adapting |
Merkel's disc
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who am I?
located around hair roots and under skin surface responds to various stimuli variable adaptation |
free nerve endings
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define two point discrimination
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the minimum distance necessary to differentiate between two points touching the body simultaneously
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what is the function of primary afferent neurons?
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to carry sensory signals to the brain
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where do primary afferent neurons enter the spinal cord?
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through the dorsal roots.
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where are the cell bodies located that are associated with primary afferent axons?
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in the dorsal root ganglion
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what are the three different types of sensory nerve fibers?
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A beta
A delta C |
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who am I?
thick fastest conducting signal MYLENATED heavily sensory- mechanoreceptors in the skin |
A beta
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who am I?
medium thickness medium speed lighly myelinated sensory- cold, fast pain, mechanical stimuli |
A delta
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who am I?
thin layer slowest conducting signal no myelination sensory- slow pain, heat, cold, mechanical stimuli |
C
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where is the somatosensory cortex in the brain?
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the parietal lobe
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what is the somatosensory cortex also known as?
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post-central gyrus
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what are the brodmann area's associated with the somatosensory cortex?
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1, 2, 3a, 3b
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what is located at brodmann area 3b ?
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primary somatosensory cortex
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what is the somatotropic map a map of?
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the somatosensory cortex
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what does each portion of the somatosensory cortex represent?
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a different part of the body. The amount of space given to each part is correlated to how sensitive it is.
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define cortical map plasiticity
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cortical maps are dynamic and adjust depending on the amount of sensory experience
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who am I?
feel pain, free nerve endings in the skin. These nerve endings respond to noxious stimuli, or potentially damaging stimuli to the tissue |
Nociceptor
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Nociceptor channels open b/c of what chemical signals?
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ATP, K+, Bradykinin
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what are the 4 different nociceptors?
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polymodal
mechanical thermal chemical |
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what is the really neat thing about vanilloid R?
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it can detect heat from temperature and from hot sauce
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what sensory nerve fiber am I ?
I feel the initial pain? |
A delta
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what sensory nerve fiber am I?
slow itch, pain |
C
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what is the gate-control theory of pain?
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painful stimulus is trying to send info to the brain, its trying to switch of the inhibitory interneuron. At the same time you give a mechanical non-painful stimulus, this info is given by A beta fibers switches inhibitory back on. It can override the C fibers to shut off the inhibitory
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what do prostoglandins do?
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shut off the COX pathway
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who is safer, cox 1 or cox 2?
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cox 2, we need cox 1 to be switched on so we dont have GI bleeding
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