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43 Cards in this Set

  • Front
  • Back
how does the brain make sense of touch?
transduces so neuron can understand it (ISPS or ESPS). The transduction sends an intercelluar signal to the CNS
define stimulus
physical energy that activates the receptor.
how does transduction occur
ransduces to intercellular signal via opening ion channels, switching on second messenger systems sends signal to CNS so we know our arm has been touched.
what are the 4 sensory receptors?
chemoreceptor
mechanoreceptor
photoreceptor
thermoreceptor
Define adequate stimuli
any of the 4 sensory receptors that the stimuli is most responsive to
define transduction
converting physical signals into intercellular signals that the CNS can understand
define threshold
minimum amount of stimuli needed to activate EPSP or IPSP
define graded potential
change in the membrane potential in response to the stimulus
define ESPS
depolarization, bring M.P. closer to threshold for A.P.
define ISPS
inhibitory, increasing M.P. further from threshold from A.P.
define receptor potential
produced when receptor is activated by its adequate stimulus and above threshold. Changes in M.P. in response to the stimulus.
What are the steps in the pathway to the cortex?
Primary S.N. has sensory receptors in it, transduce stimulus

send signal to second S.N.
send signal to thalamus
send signal to the cortexx
where does fine touch decussate?
in the medulla
where does pain/temp decussate?
in the spinal cord
who am I?
Mechanical stimuli- vibration
deep in dermis
large receptive field
rapidly adapting
Pacinian corpuscles
who am I?

mechanical stimli-stretching
deep in dermis
lg. receptive field
slowly adapting?
Ruffini
who am I?
mechanical-flutter/ stroke
located in the fingertips
small receptive fields
slowly adapting
Meissners
Who am I?
mechanical- steady pressure and texture
superficial layers of the skin
small receptive field
slowly adapting
Merkel's disc
who am I?
located around hair roots and under skin surface
responds to various stimuli
variable adaptation
free nerve endings
define two point discrimination
the minimum distance necessary to differentiate between two points touching the body simultaneously
what is the function of primary afferent neurons?
to carry sensory signals to the brain
where do primary afferent neurons enter the spinal cord?
through the dorsal roots.
where are the cell bodies located that are associated with primary afferent axons?
in the dorsal root ganglion
what are the three different types of sensory nerve fibers?
A beta
A delta
C
who am I?
thick
fastest conducting signal
MYLENATED heavily
sensory- mechanoreceptors in the skin
A beta
who am I?
medium thickness
medium speed
lighly myelinated
sensory- cold, fast pain, mechanical stimuli
A delta
who am I?
thin layer
slowest conducting signal
no myelination
sensory- slow pain, heat, cold, mechanical stimuli
C
where is the somatosensory cortex in the brain?
the parietal lobe
what is the somatosensory cortex also known as?
post-central gyrus
what are the brodmann area's associated with the somatosensory cortex?
1, 2, 3a, 3b
what is located at brodmann area 3b ?
primary somatosensory cortex
what is the somatotropic map a map of?
the somatosensory cortex
what does each portion of the somatosensory cortex represent?
a different part of the body. The amount of space given to each part is correlated to how sensitive it is.
define cortical map plasiticity
cortical maps are dynamic and adjust depending on the amount of sensory experience
who am I?
feel pain, free nerve endings in the skin. These nerve endings respond to noxious stimuli, or potentially damaging stimuli to the tissue
Nociceptor
Nociceptor channels open b/c of what chemical signals?
ATP, K+, Bradykinin
what are the 4 different nociceptors?
polymodal
mechanical
thermal
chemical
what is the really neat thing about vanilloid R?
it can detect heat from temperature and from hot sauce
what sensory nerve fiber am I ?
I feel the initial pain?
A delta
what sensory nerve fiber am I?

slow itch, pain
C
what is the gate-control theory of pain?
painful stimulus is trying to send info to the brain, its trying to switch of the inhibitory interneuron. At the same time you give a mechanical non-painful stimulus, this info is given by A beta fibers switches inhibitory back on. It can override the C fibers to shut off the inhibitory
what do prostoglandins do?
shut off the COX pathway
who is safer, cox 1 or cox 2?
cox 2, we need cox 1 to be switched on so we dont have GI bleeding